Cilt:3 Sayı: 02
Güncel Gönderiler
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Investigation of dual AChE/MAO inhibitory activities of new morpholine and piperazine structured compounds
(Anadolu Üniversitesi, 2024)In this study, a series of new compounds containing piperazine and morpholine rings were synthesized. Characterization studies of the obtained compounds were carried out with the help of HRMS, 1H-NMR and 13C-NMR spectroscopic ... -
Synthesis of new 1,3,4-thiadiazole derivatives, investigation of their AChE effects
(Anadolu Üniversitesi, 2024)Alzheimer’s disease (AD) is the most common cause of dementia and one of the most prevalent neurodegenerative diseases. It begins with mild cognitive impairment and progressively affects all aspects of the patient’s life ... -
Synthesis of some benzothiazole-piperazine derivatives, investigation by in vitro and molecular modelling for hMAO inhibitory activities
(Anadolu Üniversitesi, 2024)Monoamine oxidase (MAO) is an enzyme that helps regulate the functions of intracellular amines, as well as chemicals such as dopamine, serotonin and norepinephrine, in the brain and its tissues. Active substances that are ... -
Synthesis of a new thiadiazole-benzodioxole derivative, investigation of acetylcholinesterase inhibition with in vitro and in silico studies
(2024)Alzheimer’s disease is a progressive and degenerative brain disease that negatively affects people’s lives and reduces cognitive and sensory human functions. Today, there are active ingredients that work on Alzheimer’s ... -
Phytochemical quality analysis of commercial preparations containing Echinacea purpurea
(Anadolu Üniversitesi, 2024)Echinacea species have been medicinally important plants from the past to the present. Echinacea is used in many diseases, especially cold and wound treatment. The root, flower, and leaf parts of the plant, especially the ...
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