Yayıncı "Wiley-V C H Verlag GMBH" Eczacılık Fakültesi için listeleme
Toplam kayıt 28, listelenen: 1-20
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1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-beta-lactamases
(Wiley-V C H Verlag GMBH, 2017)Metallo-beta-lactamases (MBLs) cause resistance of Gram-negative bacteria to beta-lactam antibiotics and are of serious concern, because they can inactivate the last-resort carbapenems and because MBL inhibitors of clinical ... -
Antidiabetic potential: In vitro inhibition effects of bromophenol and diarylmethanones derivatives on metabolic enzymes
(Wiley-V C H Verlag GMBH, 2018)Aldose reductase converts glucose to sorbitol in the polyol pathway. It is an important enzyme to prevent diabetic complications. In this study, we studied the inhibitory effects of bromophenol derivatives on aldose reductase ... -
Bioactive constituents from Turkish Pimpinella species
(Wiley-V C H Verlag GMBH, 2005)A new 'phenylpropanoid', 4-(3-methyloxiran-2-yl)phenyl 2-methylbutanoate (1), a new trinorsesquiterpene, 4-(6-methylbicyclo[4.1.0]hept-2-en-7-yl)butan-2-one (2), and eight known compounds (3-10) were isolated from the ... -
Biotransformation of (-)-(R)-a-Phellandrene: Antimicrobial Activity of Its Major Metabolite
(Wiley-V C H Verlag GMBH, 2012)Terpene derivatives converted by microbial biotransformation constitute an important resource for natural pharmaceutical, fragrance, and aroma substances. In the present study, the monoterpene a-phellandrene was biotransformed ... -
A capillary zone electrophoretic method for the determination of nimesulide in pharmaceutical preparation and serum
(Wiley-V C H Verlag GMBH, 2001)A simple capillary zone electrophoretic (CZE) method was developed to determine nimesulide in pharmaceutical tablet formulations and serum. Method development was conducted in a fused-silica capillary using a background ... -
Carbazoles and Hydrazone-Bridged Thiazole-Pyrrole Derivatives as New Inhibitors of alpha-Glucosidase
(Wiley-V C H Verlag GMBH, 2018)Carbazoles and hydrazone-bridged thiazole-pyrrole derivatives are known to exhibit a wide range of biological activities including antimicrobial activity. This work is a further extension of their biological activities ... -
Chemical Composition and Biological Activity of Centaurea baseri: New Species from Turkey
(Wiley-V C H Verlag GMBH, 2016)The genus Centaurea L. is one of the largest and important genera of Asteraceae family. Centaurea species have been widely used as herbal remedies in folk medicine for their antidandruff, antidiarrheic, antirheumatic, ... -
Chemical Diversity of Volatiles of Teucrium orientale L. var. orientale, var. puberulens, and var. glabrescens Determined by Simultaneous GC-FID and GC/MS Techniques
(Wiley-V C H Verlag GMBH, 2012)In the present work, three varieties of Teucrium orientale, var. orientale, var. puberulens, and var. glabrescens, were collected and investigated for chemical composition of the oils. Subsequent gas chromatography (GC-FID) ... -
Comparative study of different chemistries and particle properties, high-performance liquid chromatography stationary phases in separation of escitalopram oxalate and its impurities in different pharmaceutical dosage forms
(Wiley-V C H Verlag GMBH, 2019)The liquid chromatographic separation performance of 12 different columns was evaluated for the estimation of the escitalopram oxalate and six of its impurities in different pharmaceutical formulations. All columns exhibited ... -
Compositions of Essential Oils and Trichomes of Teucrium chamaedrys L. subsp trapezunticum RECH. fil. and subsp syspirense (C. KoCH) RECH. fil.
(Wiley-V C H Verlag GMBH, 2009)Teucrium chamaedrys L. is a member of the Lamiaceae family and is represented in the Flora of Turkey by six subspecies. The aerial organs of 7: chamaedrys L. subsp. trapezunticum RECH. fit. and subsp. syspirense (C. KOCH) ... -
Design, synthesis, in vitro and in silico evaluation of new pyrrole derivatives as monoamine oxidase inhibitors
(Wiley-V C H Verlag GMBH, 2018)In an effort to develop potent monoamine oxidase (MAO) inhibitors, new pyrrole derivatives were obtained via the selective reduction of the CC bonds of 1-(1-methyl-1H-pyrrol-2-yl)-3-[5-(aryl)furan-2-yl]prop-2-en-1-ones ... -
Determination of Amlodipine in pharmaceutical formulations by differential-pulse voltammetry with a glassy carbon electrode
(Wiley-V C H Verlag GMBH, 2002)A differential-pulse voltammetric method was developed for the determination of amlodipine based on the oxidation of the dihydropyridine group on the surface of glassy carbon electrode under stationary and rotating conditions. ... -
Determination of formoterol by capillary electrophoresis and its application to inhaler capsules
(Wiley-V C H Verlag GMBH, 2003)A capillary electrophoretic (CE) method for the determination of formoterol (FOR) in a pharmaceutical preparation is described. Analysis was made in a background electrolyte consisting of 20 % acetonitrile and 50 mM ... -
Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes
(Wiley-V C H Verlag GMBH, 2019)Hexane extracts of Heracleum verticillatum, H. sibiricum, H. angustisectum, and H. ternatum were studied for their furanocoumarin content antioxidant potential and acetylcholinesterase and -amylase inhibitory activities. ... -
HPLC determination of cefprozil in tablets using monolithic and C-18 silica columns
(Wiley-V C H Verlag GMBH, 2011)Cefprozil (CPZ) is a second-generation semi-synthetic cephalosporin antibiotic that commonly exists as the mixture of Z and E diastereoisomers, at the ratio of approximately 9:1. A novel reversed-phase HPLC method for the ... -
New, sesquiterpenoid-type bicyclic compounds from the buds of Betula pubescens - Ring-contracted products of beta-caryophyllene?
(Wiley-V C H Verlag GMBH, 2004)The essential oils obtained from the buds of Betula pubescens ssp. pubescens and B. pubescens ssp. czerepanovii were analyzed both by GC and GC/MS and, of the 31 compounds identified, 14-acetoxy-beta-caryophyllene was ... -
One-step multiple component isolation from the oil of Crinitaria tatarica (Less.) Sojak by preparative capillary gas chromatography with characterization by spectroscopic and spectrometric techniques and evaluation of biological activity
(Wiley-V C H Verlag GMBH, 2012)Gas chromatographic analysis revealed that the oil of Crinitaria tatarica was rich in sabinene (32.1%), beta-pinene (8.8%), and two unknown (M+200) compounds (I) and (II) (21.4% and 3.4%). One-step multiple fractionation ... -
Pyridine-substituted thiazolylphenol derivatives: Synthesis, modeling studies, aromatase inhibition, and antiproliferative activity evaluation
(Wiley-V C H Verlag GMBH, 2018)Drugs used in breast cancer treatments target the suppression of estrogen biosynthesis. During this suppression, the main goal is to inhibit the aromatase enzyme that is responsible for the cyclization and structuring of ... -
Studies on 1,2,4-triazole derivatives as potential anti-inflammatory agents
(Wiley-V C H Verlag GMBH, 2007)The reaction of acetic or propionic acid hydrazides with various aryl/alkyl isothiocyanates gave thiosemicarbazides which furnished the 1,2,4-triazoles by alkali cyclization. The 4-aryl/allcyl-5-(1phenoxyethyl)-3-[N-(sub ... -
Synthesis and antibacterial activity of tert-butyl [1-benzyl-2[(4-aryl-2-thiazolyl)hydrazono]ethyl]carbamate derivatives
(Wiley-V C H Verlag GMBH, 2007)The increasing clinical importance of drug-resistant fungal and bacterial pathogens has lent additional urgency to microbiological research and new antibacterial compound development. For this purpose, new tent-butyl[1-b ...