Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes
![Thumbnail](/xmlui/bitstream/handle/11421/12857/12857.pdf.jpg?sequence=5&isAllowed=y)
Göster/ Aç
Erişim
info:eu-repo/semantics/openAccessTarih
2019Yazar
Özek, GülmiraYur, Süleyman
Göğer, Fatih
Özek, Temel
Andjelkovic, Boban
Godjevac, Dejan
Trendafilova, Antoaneta
Üst veri
Tüm öğe kaydını gösterÖzet
Hexane extracts of Heracleum verticillatum, H. sibiricum, H. angustisectum, and H. ternatum were studied for their furanocoumarin content antioxidant potential and acetylcholinesterase and -amylase inhibitory activities. Quantification of the furanocoumarins was performed by H-1-NMR. Pimpinellin was found to be the main component in the roots of all studied species. Bergapten and imperatorin were the major compounds in the fruits of H. sibiricum and H. verticillatum, respectively, while byakangelicol dominated in H. angustisectum and H. ternatum fruits. The leaf and fruit extracts of H. angustisectum demonstrated the highest DPPH radical scavenging activity and TEAC (IC50 0.58mg/mL and 1.83mm, respectively). The root extracts of H. verticillatum and H. angustisectum were found to be the most effective against acetylcholinesterase (IC50 0.30 and 0.34mg/mL, respectively). The studied extracts were not active or demonstrated a weak inhibitory effect (%Inh. up to 29.7) towards -amylase.
Kaynak
Chemistry & BiodiversityCilt
16Sayı
4Koleksiyonlar
İlgili Öğeler
Başlık, yazar, küratör ve konuya göre gösterilen ilgili öğeler.
-
Comparative study of the essential oils of Heracleum sphondylium ssp ternatum obtained by micro- and hydro-distillation methods
Özek, Temel; Demirci, Betül; Başer, K. Hüsnü Can (Consultants Bureau, 2002)The volatile compounds obtained by hydro- and micro-distillation methods from crushed fruits of Heracleum sphondylium ssp. ternatum (Velen.) Brummitt were analyzed by GC/MS. Both distillation methods and analysis results ... -
The bioactive essential oil of Heracleum sphondylium L. subsp. ternatum (Velen.) Brummitt
İşcan, Gökalp; Demirci, Fatih; Kürkçüoğlu, Mine; Kıvanç, Merih; Başer, K. Hüsnü Can (Verlag der Zeitschrift fur Naturforschung, 2003)The essential oil of Heracleum sphondylium L. subsp. ternatum (Velen.) Brummit (Umbelliferae) was isolated from crushed seeds by means of hydrodistillation and analyzed by GC and GC/MS. Major components were identified as ... -
Composition of the Essential Oil of Heracleum platytaenium Boiss. From Turkey
Water-distilled essential oils from the crushed fruits of Heracleum platytaenium, an endemic species collected from two localities in Turkey were analyzed by capillary GC and GC/MS. Ten compounds representing 94.36% and ...