Bioavailability file: Piribedil [Biyoyararlanim dosyasi: Piribedil]

Abstract

Piribedil is a dopamin agonist with vasodilator activity and whose aqueous solubility is low and elimination half-life is short. It is widely used in cerebral ageing and in Parkinson's disease. Literature on physico-chemical and pharmacological properties, analysis methods, bioavailability and pharmacokinetics of piribedil has been reviewed in this article.