Farmasötik Teknoloji Anabilim Dalı
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Dexketoprofen trometamol loaded solid lipid nanoparticles(SLNs): Formulation, in vitroand in vivoevaluation
(2020)Development, in vitroand in vivoevaluation of dexketoprofen trometamol (DT)-loaded nanosizeddrugdelivery system was aimed in this study. DT-loaded solid lipid nanoparticles (SLNs) were prepared using probe ... -
New approach to hypertension treatment: Carvediol-loaded PLGA nanoparticles, preparation, in vitro characterization and gastrointestinal stability
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2018)Carvedilol (CVL) has advantages over the first generation of ß-blockers in patients with heart failure due to its properties of reducing cardiovascular morbidity and mortality. On the other hand, CVL has a short half-life ... -
Effects of different derivatives of eudragit polymer on entrapment efficiency, in vitro dissolution, release kinetics and cell viability results on extended release flurbiprofen loaded nanomedicines
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2018)The purpose of the present investigation was to design and compare the release characteristics of sustained-release formulations of Flurbiprofen (FLB) loaded nanoparticles (NPs) by using spray-dryer technique using Eudragit ... -
Release of vitamin E from different topical colloidal delivery systems and their in vitro-in vivo evaluation
(2010)Bu çalışmada, E vitamini yüklenmiş topik uygulanabilir y/s mikroemülsiyonu (ME), y/s basit emülsiyonu (SE) ve katı lipit nanopartikül (SLN) kozmetik taşıyıcı sistemleri hazırlanmıştır. Sistemlerin karakterizasyonu için ... -
Desloratidin-Euragit® RS100 Nanopartikülleri: Formülasyon ve Karakterizasyon
(2017)Amaç: Bu çalışmanın amacı, Desloratadin-Eudragit® RS100 nanopartiküllerini formüle etmek ve hazırlanan nanopartiküllerin özelliklerini araştırmaktır.Gereç ve Yöntemler: Nanopartiküller püskürterek kurutma yöntemi ile ... -
Formulation and characterization of a cosmetic multiple emulsion system containing macadamia nut oil and two anti aging agents
(2005)Bu çalışmanın amacı, doğal bir yağ kullanarak, iki farklı cilt yaşlanmasını geciktirici madde içeren kararlı emülsiyon sistemini hazırlamaktır. Çok kararsız ve oksijen varlığında yapısının parçalandığı bilinen vitamin C, ... -
Physicochemical characterization and dissolution properties of cinnarizine solid dispersions
(2005)Sudaki çözünürlüğü düşük olarak bilinen kalsiyum antagonisti sinnarizinin biyoyararlanımı değişken veya düşüktür. Bu özellikteki bir ilaç materyalinin çözünme davranışının iyileştirilmesi, oral biyoyararlanımı geliştirebilir. ... -
Pharmacological and pharmaceutical technological overview for seborrheic dermatitis: A review about topical application and new approaches
(İstanbul Medipol University, 2018)Seborrheic dermatitis (SD) is a skin disease with chronic recurrent erythematous plaques in areas where sebaceous glands are intense. The etiology of SD remains unknown, although many factors such as lipophilic yeasts of ... -
Preparation and in vitro evaluation of in situ gelling system containing lithium carbonate for parenteral administration
(Springer Verlag, 2019)Lithium is the principal and the most effective drug in the treatment of bipolar disorder since the middle of the previous century. However, narrow therapeutic range and side effect profile of lithium necessitate its careful ... -
Formulation and in vitro evaluation of moxifloxacin hydrochloride-loaded polymeric nanoparticles for ocular application
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2018)The primary purpose of this study was to extend the time of interaction of the carrier with the negatively charged ocular surface for enhanced penetration in order to improve ocular bioavailability. Moxifloxacin hydrochloride ... -
Development of nano-sized ketoprofen lysine incorporated Eudragit® S100 nanomedicine by double emulsion solvent evaporation and in vitro characterization
(Academic Association of Pharmaceutical Sciences from Antofagasta (ASOCIFA), 2019)Context: Pain has a very important effect on the biological, psychological, sociological and economic situation of a patient. Nanoparticles (NPs) are being extensively investigated as drug delivery systems worldwide for ... -
Preparation and in vitro characterization of a fluconazole loaded chitosan particulate system
(İstanbul Medipol University, 2019)In the present study fluconazole (FZ) was successfully incorporated into cationic chitosan nanoparticles prepared by spray-drying method aiming dermal delivery. Particle size and zeta potential measurements, drug content, ... -
Dexketoprofen trometamol-loaded eudragit® rl 100 nanoparticle formulation, characterization and release kinetics
(İstanbul Medipol University, 2019)Development and in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized and controlled release drug delivery system was aimed in this study. DT-loaded Eudragit® RL 100 polymeric nanoparticles were prepared ... -
Development and validation of uplc method for the determination of olopatadine hydrochloride in polymeric nanoparticles
(İstanbul Medipol University, 2019)A new, simple, rapid, precise, accurate and specific stability indicating reverse phase UPLC method developed for the determination of encapsulated olopatadine hydrochloride (OLO) in the polymeric nanoparticle formulations. ... -
Flurbiprofen loaded gel based topical delivery system: Formulation and in vitro characterization with new developed UPLC method
(İstanbul Medipol University, 2018)Objective: The purpose of this study was to formulate flurbiprofen (FLB) loaded methylcellulose (MC), hydroxypropyl methylcellulose (HPMC) and Carbopol®940 (C-940) based gel formulations with the help of dispersion method ... -
Influence of glyceryl behenate, tripalmitin and stearic acid on the properties of clarithromycin incorporated solid lipid nanoparticles (SLNs): Formulation, characterization, antibacterial activity and cytotoxicity
(Editions de Sante, 2019)Clarithromycin (CLR) is a macrolide derivative which is included in BCS class 2 with low oral bioavailability. Solid lipid nanoparticles (SLNs) have been studied by many researchers for drug application and are very popular ... -
Design and characterization of montelukast sodium loaded kollidon® SR nanoparticles and evaluation of release kinetics and cytotoxicity potential
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2019)The objective of this research was to design and characterize montelukast sodium (MS) loaded novel nanosized and biocompatible Kollidon® SR nanoparticles to provide prolonged release behavior that can improve bioavailability, ... -
Ornidazole incorporated chitosan nanoparticles for ocular application
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2015)Considering the low ocular bioavailability of conventional formulations used for ocular bacterial infection treatment, there is a need for developing efficient modern drug delivery systems. Main attempt in this study was ... -
The effect of solid lipid nanoparticles on tamoxifen-resistant breast cancer cells
(Innovare Academics Sciences Pvt. Ltd, 2016)To overcome the acquired Tamoxifen (Tam) resistance in Tam-resistant breast cancer cells without damaging normal cells, we have examined the therapeutic efficacy of Tam-loaded solid lipid nanoparticles (SLNs). Tam-loaded ... -
Dexketoprofen trometamol-loaded kollidon® SR and eudragit® RS 100 polymeric nanoparticles: Formulation and in vitro-in vivo evaluation
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2017)Development and in vivo/in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized, controlled release drug delivery system was aimed in this study.. DT-loaded Kollidon® SR (KSR) and Eudragit® RS 100 (ERS) ...
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