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Toplam kayıt 76, listelenen: 61-76
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Formulation and in vitro evaluation of moxifloxacin hydrochloride-loaded polymeric nanoparticles for ocular application
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2018)The primary purpose of this study was to extend the time of interaction of the carrier with the negatively charged ocular surface for enhanced penetration in order to improve ocular bioavailability. Moxifloxacin hydrochloride ... -
Effects of Different Derivatives of Eudragit Polymer on Entrapment Efficiency, In Vitro Dissolution, Release Kinetics and Cell Viability Results on Extended Release Flurbiprofen Loaded Nanomedicines
(Colegio Farmaceuticos Provincia De Buenos Aires, 2018)The purpose of the present investigation was to design and compare the release characteristics of sustained-release formulations of Flurbiprofen (FLB) loaded nanoparticles (NPs) by using spray-dryer technique using Eudragit ... -
Flurbiprofen loaded gel based topical delivery system: Formulation and in vitro characterization with new developed UPLC method
(İstanbul Medipol University, 2018)Objective: The purpose of this study was to formulate flurbiprofen (FLB) loaded methylcellulose (MC), hydroxypropyl methylcellulose (HPMC) and Carbopol®940 (C-940) based gel formulations with the help of dispersion method ... -
Design and Characterization of Montelukast Sodium Loaded Kollidon (R) SR Nanoparticles and Evaluation of Release Kinetics and Cytotoxicity Potential
(Colegio Farmaceuticos Provincia De Buenos Aires, 2019)The objective of this research was to design and characterize montelukast sodium (MS) loaded novel nanosized and biocompatible Kollidon (R) SR nanoparticles to provide prolonged release behavior that can improve bioavailability, ... -
Development of nano-sized ketoprofen lysine incorporated Eudragit (R) S100 nanomedicine by double emulsion solvent evaporation and in vitro characterization
(Journal Pharmacy & Pharmacognosy Research-Jppres, 2019)Context: Pain has a very important effect on the biological, psychological, sociological and economic situation of a patient. Nanoparticles (NPs) are being extensively investigated as drug delivery systems worldwide for ... -
Influence of glyceryl behenate, tripalmitin and stearic acid on the properties of clarithromycin incorporated solid lipid nanoparticles (SLNs): Formulation, characterization, antibacterial activity and cytotoxicity
(Editions de Sante, 2019)Clarithromycin (CLR) is a macrolide derivative which is included in BCS class 2 with low oral bioavailability. Solid lipid nanoparticles (SLNs) have been studied by many researchers for drug application and are very popular ... -
Preparation and in vitro characterization of a fluconazole loaded chitosan particulate system
(İstanbul Medipol University, 2019)In the present study fluconazole (FZ) was successfully incorporated into cationic chitosan nanoparticles prepared by spray-drying method aiming dermal delivery. Particle size and zeta potential measurements, drug content, ... -
Development of nano-sized ketoprofen lysine incorporated Eudragit® S100 nanomedicine by double emulsion solvent evaporation and in vitro characterization
(Academic Association of Pharmaceutical Sciences from Antofagasta (ASOCIFA), 2019)Context: Pain has a very important effect on the biological, psychological, sociological and economic situation of a patient. Nanoparticles (NPs) are being extensively investigated as drug delivery systems worldwide for ... -
Cefaclor monohydrate loaded microemulsion formulation for topical application: Characterization with new developed UPLC method and stability study
(Marmara University, 2019)The purpose of this study was to formulate Cefaclor monohydrate (CEF) loaded microemulsion formulations with the help of pseudo-ternary phase diagrams for topical application. Additionally, in this study also a new ... -
Dexketoprofen trometamol-loaded poly-lactic-co-glycolic acid (PLGA) nanoparticles: Preparation, in vitro characterization and cyctotoxity
(Pharmacotherapy Group, 2019)Purpose: To design, formulate and characterize sustained-release formulations of dexketoprofen trometamol (DT) nanoparticles (NPs) Methods: Dexketoprofen trometamol (DT)-loaded poly(lactic-co-glycolic acid) (PLGA) NPs were ... -
Dexketoprofen trometamol-loaded eudragit® rl 100 nanoparticle formulation, characterization and release kinetics
(İstanbul Medipol University, 2019)Development and in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized and controlled release drug delivery system was aimed in this study. DT-loaded Eudragit® RL 100 polymeric nanoparticles were prepared ... -
Development and validation of uplc method for the determination of olopatadine hydrochloride in polymeric nanoparticles
(İstanbul Medipol University, 2019)A new, simple, rapid, precise, accurate and specific stability indicating reverse phase UPLC method developed for the determination of encapsulated olopatadine hydrochloride (OLO) in the polymeric nanoparticle formulations. ... -
Olopatadine hydrochloride loaded Kollidon (R) SR nanoparticles for ocular delivery: Nanosuspension formulation and in vitro-in vivo evaluation
(Elsevier Science BV, 2019)Introduction: Allergic eye diseases includes a spectrum of diseases, with each state being characterized by a complicated immunopathology. In the present study, polymeric Kollidon (R) SR nanoparticles loaded with olopatadine ... -
Preparation and in vitro evaluation of in situ gelling system containing lithium carbonate for parenteral administration
(Springer Verlag, 2019)Lithium is the principal and the most effective drug in the treatment of bipolar disorder since the middle of the previous century. However, narrow therapeutic range and side effect profile of lithium necessitate its careful ... -
Design and characterization of montelukast sodium loaded kollidon® SR nanoparticles and evaluation of release kinetics and cytotoxicity potential
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2019)The objective of this research was to design and characterize montelukast sodium (MS) loaded novel nanosized and biocompatible Kollidon® SR nanoparticles to provide prolonged release behavior that can improve bioavailability, ... -
Dexketoprofen trometamol loaded solid lipid nanoparticles(SLNs): Formulation, in vitroand in vivoevaluation
(2020)Development, in vitroand in vivoevaluation of dexketoprofen trometamol (DT)-loaded nanosizeddrugdelivery system was aimed in this study. DT-loaded solid lipid nanoparticles (SLNs) were prepared using probe ...