Ara
Toplam kayıt 92, listelenen: 41-50
Ocular Application of Dirithromycin Incorporated Polymeric Nanoparticles: an In Vitro Evaluation
(Turkish Pharmacists Assoc, 2017)
Objectives: Ocular drug delivery is a difficult challenge especially with topical intillation which results in rapid drainage and non-productive drug absorption. For the improvement of the pre-corneal retention time and ...
In vitro/in vivo evaluation of gamma-aminobutyric acid-loaded N,N-dimethylacrylamide-based pegylated polymeric nanoparticles for brain delivery to treat epilepsy
(Taylor & Francis LTD, 2016)
Objectives of this study were the delivery of gamma aminobutyric acid (GABA) into the brain by means of developing brain targeted, nanosized, non-toxic and biocompatible polymeric nanoparticles, and investigating their ...
Ornidazole incorporated chitosan nanoparticles for ocular application
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2015)
Considering the low ocular bioavailability of conventional formulations used for ocular bacterial infection treatment, there is a need for developing efficient modern drug delivery systems. Main attempt in this study was ...
Propranolol HCl imprinted polymeric microspheres: Development, characterization and dissolution
(2007)
Specificity to target molecule, high selectivity and sensitivity to release and targeting were achieved using molecularly imprinted polymer (MIP) systems. In this study, propranolol HCl (PHCL) imprinted methacryloylamido ...
Sunblocking efficiency of various TiO2-loaded solid lipid nanoparticle formulations
(2006)
In this study, titanium dioxide (TiO2) was incorporated into solid lipid nanoparticle (SLN) formulations using both classical and novel preparation methods. The SLNs were investigated by evaluating their stabilities and ...
The effect of solid lipid nanoparticles on tamoxifen-resistant breast cancer cells
(Innovare Academics Sciences Pvt. Ltd, 2016)
To overcome the acquired Tamoxifen (Tam) resistance in Tam-resistant breast cancer cells without damaging normal cells, we have examined the therapeutic efficacy of Tam-loaded solid lipid nanoparticles (SLNs). Tam-loaded ...
Dexketoprofen trometamol-loaded kollidon® SR and eudragit® RS 100 polymeric nanoparticles: Formulation and in vitro-in vivo evaluation
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2017)
Development and in vivo/in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized, controlled release drug delivery system was aimed in this study.. DT-loaded Kollidon® SR (KSR) and Eudragit® RS 100 (ERS) ...
Studies on rosuvastatin calcium incorporated chitosan salt nanoparticles
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2016)
Cardiovascular diseases are the leading causes of death worldwide and rosuvastatin calcium (RCa) is one of the most effective drugs used for the prevention of coronary heart diseases. Considering low aqueous solubility ...
Enhanced bioavailability of cinnarizine using solid dispersion: In vitro and in vivo evaluation
(Bentham Science Publishers B.V., 2015)
The aim of this study was to modify the release and thus enhance the bioavailability of acalcium antagonist cinnarizine whose aqueouse solubility is low and half-life is short. For this purpose, solid dispersion system was ...
Voriconazole incorporated polymeric nanoparticles for ocular application
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2017)
Limitations of topical ocular application lead to unsufficient treatment in severe ocular disorders, therefore the researchers focused on novel drug delivery systems for the achievement of enhanced ocular bioavailability. ...