Ara
Toplam kayıt 92, listelenen: 31-40
Preparation and characterization of methotrexate-loaded microcapsules
(Taylor & Francis LTD, 2014)
Methotrexate (MTX) has toxic effect to healthy tissues. Microencapsulation coats particles with a functional coat to optimize storage stability and to modulate release. In the present study, a new MTX encapsulated microcapsules ...
Studies on prolonged release matrix tablet formulations of hydralazine hydrochloride
(2003)
The purpose of this study was to prepare prolonged release tablet formulations of hydralazine hydrochloride which has been used as an antihypertensive agent. To achieve this, carbomers (Carbopol® 834, 934, 940 and 1342) ...
Characterization of Solid Lipid Nanoparticles Containing Caffeic Acid and Determination of its Effects on MCF-7 Cells
(Bentham Science Publ LTD, 2015)
Many anticancer drugs that are currently used in cancer treatment are natural products or their analogues by structural modification. Caffeic acid (3, 4-dihydroxycinnamic acid; CA) is classified as hydroxycinnamic acid and ...
The aggregation behavior of trimetazidine hydrochloride in aqueous solutions at different temperatures
(Elsevier Science BV, 2015)
The aggregation behavior of trimetazidine hydrochloride (TMZ HCl) in aqueous solutions has been investigated by electrical conductivity, ultrasonic speed and density measurements in the temperature ranges from 298.15 to ...
Physicochemical characterization and dissolution properties of cinnarizine solid dispersions
(2005)
Sudaki çözünürlüğü düşük olarak bilinen kalsiyum antagonisti sinnarizinin biyoyararlanımı değişken veya düşüktür. Bu özellikteki bir ilaç materyalinin çözünme davranışının iyileştirilmesi, oral biyoyararlanımı geliştirebilir. ...
Supervised Machine Learning Algorithms for Evaluation of Solid Lipid Nanoparticles and Particle Size
(Bentham Science Publ LTD, 2018)
Aims and Objectives: Solid Lipid Nanoparticles (SLNs) are pharmaceutical delivery systems that have advantages such as controlled drug release, long-term stability etc. Particle Size (PS) is one of the important criteria ...
Preparation and characterization of polymeric and lipid nanoparticles of pilocarpine HCl for ocular application
(Informa Healthcare, 2013)
Pilocarpine is used topically in the treatment of glaucoma. Various studies were performed to improve the bioavailability and prolong the residence time of drugs in ocular drug delivery. Drug loaded polymeric and lipid ...
New approach to hypertension treatment: Carvediol-loaded PLGA nanoparticles, preparation, in vitro characterization and gastrointestinal stability
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2018)
Carvedilol (CVL) has advantages over the first generation of ß-blockers in patients with heart failure due to its properties of reducing cardiovascular morbidity and mortality. On the other hand, CVL has a short half-life ...
Cyclosporine-A incorporated cationic solid lipid nanoparticles for ocular delivery
(Taylor & Francis LTD, 2010)
In the present study, Cyclosporine A (CsA) was successfully incorporated into cationic solid lipid nanoparticles (SLN) for ocular application. Physicochemical characterizations of SLNs were analysed in detail during the ...
Preparation and in vitro evaluation of controlled release hydrophilic matrix tablets of ketorolac tromethamine using factorial design
(Informa Healthcare, 2008)
Controlled release matrix tablets of ketorolac tromethamine (KT) were prepared by direct compression technique using cellulose derivatives as hydroxypropylmethyl cellulose (HPMC), hydroxyethyl cellulose (HEC), and carboxymethyl ...