Yazar "Anadolu Üniversitesi, Eczacılık Fakültesi, Farmasötik Teknoloji Anabilim Dalı" için Farmasötik Teknoloji Anabilim Dalı listeleme
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Dexketoprofen trometamol-loaded kollidon® SR and eudragit® RS 100 polymeric nanoparticles: Formulation and in vitro-in vivo evaluation
Öztürk, Ahmet Alper; Yenilmez, Evrim; Arslan, Rana; Şenel, Behiye; Yazan, Yasemin (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2017)Development and in vivo/in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized, controlled release drug delivery system was aimed in this study.. DT-loaded Kollidon® SR (KSR) and Eudragit® RS 100 (ERS) ... -
Dexketoprofen trometamol-loaded poly-lactic-co-glycolic acid (PLGA) nanoparticles: Preparation, in vitro characterization and cyctotoxity
Öztürk, Ahmet Alper; Banderas, Lucia Martin; Otero, Maria D. Cayero; Yenilmez, Evrim; Senal, Behiye; Yazan, Yasemin (Pharmacotherapy Group, 2019)Purpose: To design, formulate and characterize sustained-release formulations of dexketoprofen trometamol (DT) nanoparticles (NPs) Methods: Dexketoprofen trometamol (DT)-loaded poly(lactic-co-glycolic acid) (PLGA) NPs were ... -
The effect of solid lipid nanoparticles on tamoxifen-resistant breast cancer cells
Eskiler, G. Güney; Cecener, G.; Dikmen, G.; Genç, Lütfi; Egeli, U. (Innovare Academics Sciences Pvt. Ltd, 2016)To overcome the acquired Tamoxifen (Tam) resistance in Tam-resistant breast cancer cells without damaging normal cells, we have examined the therapeutic efficacy of Tam-loaded solid lipid nanoparticles (SLNs). Tam-loaded ... -
Effects of different derivatives of eudragit polymer on entrapment efficiency, in vitro dissolution, release kinetics and cell viability results on extended release flurbiprofen loaded nanomedicines
Öztürk, Ahmet Alper; Güven, Umay Merve; Yenilmez, Evrim; Şenel, Behiye (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2018)The purpose of the present investigation was to design and compare the release characteristics of sustained-release formulations of Flurbiprofen (FLB) loaded nanoparticles (NPs) by using spray-dryer technique using Eudragit ... -
Effects of Different Derivatives of Eudragit Polymer on Entrapment Efficiency, In Vitro Dissolution, Release Kinetics and Cell Viability Results on Extended Release Flurbiprofen Loaded Nanomedicines
Öztürk, Ahmet Alper; Güven, Umay Merve; Yenilmez, Evrim; Şenel, Behiye (Colegio Farmaceuticos Provincia De Buenos Aires, 2018)The purpose of the present investigation was to design and compare the release characteristics of sustained-release formulations of Flurbiprofen (FLB) loaded nanoparticles (NPs) by using spray-dryer technique using Eudragit ... -
Enhanced bioavailability of cinnarizine using solid dispersion: In vitro and in vivo evaluation
Demirel, Müzeyyen; Büyükköroğlu, G.; Sırmagül, Başar; Kalava, B. S.; Öztürk, Nilgün; Yazan, Yasemin (Bentham Science Publishers B.V., 2015)The aim of this study was to modify the release and thus enhance the bioavailability of acalcium antagonist cinnarizine whose aqueouse solubility is low and half-life is short. For this purpose, solid dispersion system was ... -
Enhancement in dissolution pattern of piribedil by molecular encapsulation with beta-cyclodextrin
Demirel, Müzeyyen; Büyükköroğlu, G; Kalava, BS; Yazan, Yasemin (Prous Science, Sa, 2006)The aim of this was to improve the dissolution behavior of piribedil by molecular encapsulation with beta-cyclodextrin (beta-CD). Toward this aim, physical mixing, co-grinding, and spray-drying methods were used to prepare ... -
Film-coated enteric tablet formulation of ketorolac tromethamine
Genç, Lütfi; Güler, Erden; Hegazy, Nahed (Informa Healthcare, 1997)A great majority of polymers used for pharmaceutical film-coating purposes have been derivatives of cellulose or methacrylate copolymers (Eudragit series) in most recent studies. The type and frequency of the ester ... -
Flurbiprofen loaded gel based topical delivery system: Formulation and in vitro characterization with new developed UPLC method
Öztürk, Ahmet Alper; Güven, Umay Merve; Yenilmez, Evrim (İstanbul Medipol University, 2018)Objective: The purpose of this study was to formulate flurbiprofen (FLB) loaded methylcellulose (MC), hydroxypropyl methylcellulose (HPMC) and Carbopol®940 (C-940) based gel formulations with the help of dispersion method ... -
Formulation and characterization of a cosmetic multiple emulsion system containing macadamia nut oil and two anti aging agents
Akhtar, Naveed; Yazan, Yasemin (2005)Bu çalışmanın amacı, doğal bir yağ kullanarak, iki farklı cilt yaşlanmasını geciktirici madde içeren kararlı emülsiyon sistemini hazırlamaktır. Çok kararsız ve oksijen varlığında yapısının parçalandığı bilinen vitamin C, ... -
Formulation and In Vitro Evaluation of Moxifloxacin Hydrochloride-Loaded Polymeric Nanoparticles for Ocular Application
Yurtdaş Kırımlıoğlu, Gülsel; Özer, Sinan; Büyükköroğlu, Gülay; Yazan, Yasemin (Colegio Farmaceuticos Provincia De Buenos Aires, 2018)The primary purpose of this study was to extend the time of interaction of the carrier with the negatively charged ocular surface for enhanced penetration in order to improve ocular bioavailability. Moxifloxacin hydrochloride ... -
Formulation and in vitro evaluation of moxifloxacin hydrochloride-loaded polymeric nanoparticles for ocular application
Yurtdaş Kırımlıoğlu, Gülsel; Özer, S.; Büyükköroğlu, G.; Yazan, Yasemin (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2018)The primary purpose of this study was to extend the time of interaction of the carrier with the negatively charged ocular surface for enhanced penetration in order to improve ocular bioavailability. Moxifloxacin hydrochloride ... -
Formulation and in vitro-in vivo evaluation of piribedil solid lipid micro- and nanoparticles
Demirel, Müzeyyen; Yazan, Yasemin; Muller, RH; Kılıç, F; Bozan, B (Taylor & Francis LTD, 2001)Modification of the dissolution rate and, thus, the enhancement of the bioavailability of a dopaminergic drug, piribedil, which has a low aqueous solubility and short elimination half-life have been the aim in this study. ... -
Formulation and in-vivo evaluation of a cosmetic multiple emulsion containing vitamin C and wheat protein
Akhtar, Naveed; Yazan, Yasemin (University Karachi, 2008)The purpose of the study was to see the effect of two antiaging agents in one stable multiple emulsion prepared using natural oil. Vitamin C, which is a very unstable ingredient and is decomposed in the presence of oxygen, ... -
Gamma-aminobutyric acid loaded halloysite nanotubes and in vitro-in vivo evaluation for brain delivery
Kırımlıoğlu, Gülsel Yurtdaş; Yazan, Yasemin; Erol, Kevser; Unel, Çiğdem Cengelli (Elsevier Science BV, 2015)Gamma-aminobutyric acid (GABA) is a key neurotransmitter where it usually inhibits impulse transmission. GABA release blockage or postsynaptic reaction were determined to provoke epileptic convulsions. The aim of the present ... -
Improvement in the dissolution properties of theophylline with ß-cyclodextrin
Yazan, Yasemin; Sumnu, M. (1994)An improvement in the dissolution of theophylline with ß-cyclodextrin was achieved by subjecting them to co-grinding and freeze-drying methods. The products obtained were examined by the phase solubility methad, differential ... -
Improving sleep mask for eye contour care
Başyiğit, Zeynep Ömeroğulları; Hocaoğlu, E.; Kut, D.; Yenilmez, Evrim; Yazan, Yasemin (Fiber Society, 2015)[No abstract available] -
In vitro evaluation of sustained released matrix tablet formulations of clarithromycin
Genç, Lütfi; Kıran, A. M. (Osterreichische Apotheker-Verlagsgesellschaft m.b.H., 2005)Sustained release matrix tablets of clarithromycin were prepared using different polymers as Hydroxypropyl methylcellulose (HPMC), Carbopol 934 and Eudragit RL/PO by direct compression technique. For the quality control ... -
In vitro/in vivo evaluation of gamma-aminobutyric acid-loaded N,N-dimethylacrylamide-based pegylated polymeric nanoparticles for brain delivery to treat epilepsy
Kırımlıoğlu, Gülsel Yurtdaş; Menceloğlu, Yusuf; Erol, Kevser; Yazan, Yasemin (Taylor & Francis LTD, 2016)Objectives of this study were the delivery of gamma aminobutyric acid (GABA) into the brain by means of developing brain targeted, nanosized, non-toxic and biocompatible polymeric nanoparticles, and investigating their ... -
Inclusion complexes of fluconazole with beta-cyclodextrin: physicochemical characterization and in vitro evaluation of its formulation
Yurtdaş Kırımlıoğlu, Gülsel; Demirel, Müzeyyen; Genç, Lütfi (Springer, 2011)Fluconazole (FZ) is a triazole antifungal drug administered orally or intravenously. It is employed for the treatment of mycotic infections. However, the efficacy of FZ is limited with its poor aqueous solubility and low ...