Güncel Gönderiler: Farmasötik Kimya Anabilim Dalı
Toplam kayıt 345, listelenen: 41-60
-
Studies of the synthesis of some 4,5-di and 2,4,5-trisubstituted imidazole derivatives
(1989)[No abstract available] -
Synthesis of some imidazolyl-thioacetyl-pyrazolinone derivatives and their antinociceptive and anticancer activitiesal
(2010)In this study, some 4-(1,5-diarylimidazol-2-yl)thioacetyl-1-phenyl-2,3- dimethyl-3-pyrazoline-5-one derivatives were prepared by reacting 4-(2-chloroacetyl)-1-phenyl-2,3-dimethyl-3-pyrazoline-5-one and 2-mercapto-1, ... -
Cytotoxic effects of some perimidine derivatives on F2408 and 5Rp7 cell lines
(2008)In this study twenty perimidine derivatives were prepared in order to seek their cytotoxic and antiproliferative effects on normal rat embryo fibroblast (F2408) and carcinogenic rat embryo fibroblast (5RP7) cell lines. ... -
Synthesis and cytotoxic and analgesic activities of some 1, 5-diaryl-3-ethoxycarbonylpyrrole derivatives
(2006)Some 1,5-diaryl-3-ethoxycarbonyl-2-methylpyrrole derivatives were obtained by reacting 1-aryl-3-ethoxycarbonylpent-1,4-diones and a suitable aniline derivative or sulfanilamide under Paal-Knorr pyrrole synthesis conditions. ... -
Synthesis and cytotoxic activities of transition-metal complexes of a binaphthyl-linked bipyridine ligand
(2009)A binaphthyl-linked bipyridyl compound, 1,1?-bis(6-methyl-6?-oxymethylenyl- 2,2?-bipyridine)binaphthyl, (L) has been synthesised and used as a ligand for the formation of Cu(II), Ni(II), and Co(II) complexes. The ligand ... -
Studies on some new pyrazolo[3,4-c]pyridine derivatives as antimicrobial agents [Antimikrobiyal ajan olarak bazi yeni pirazolo[3,4-c]piridin türevleri üzerine çahsmalar]
(2009)The increasing clinical importance of drug-resistant bacterial and fungal pathogens has lent additional urgency to microbiological research and novel antimicrobial compounds development. For this aim, a series of N-[(Benzhydryl) ... -
Synthesis of some 2,4-di- and 2,3,4-trisubstituted benzimidazo[1,2-a] pyrimidines and evaluation of their cytotoxicities towards F2408 and 5RP7 cells
(SYSCOM 18 S.R.L., 2006)This article describes the synthesis of 2,4-di- and 2,3,4-trisubstituted benzimidazo[1,2-a]pyrimidine derivatives which were tested for their cytotoxicities and their spectral characterizations by IR, 1H- and 13C-NMR, ... -
Studies on thiazolyliminothiazoline derivatives as potential antitubercular agents
(2009)In this study, eight new ethyl {2-[3,4-diaryl-3H-thiazol-2-ylidenamino] thiazol-4-yl}acetate were synthesized by reacting ethyl [2-(3-aryl(thiouredio) thiazol-4-yl]acetate and phenacyl bromides in ethanol. The solid was ... -
Synthesis of platinum(II) complexes of 1-aryl-3-(benzimidazole-2-yl)- pyrazole-4-ketoximes and studies on their cytotoxic effects
(2008)In this research, synthesis of some complexes in the presence ofPt(II) were studied. The structure of the compounds were elucidated by IR, 1H-NMR, Mass and Elemental Analyses. The cytotoxicity of Pt-complex was evaluated. ... -
Synthesis and characterization of new binaphthyl-linked phenanthroline-, bipyridine-, or pyridine-derived ligands, and the study of their cytotoxic activity
(2008)In the present work, we describe the synthesis and characterization of five new versatile acyclic or macrocyclic ligands containing binaphthyl-linked pyridine, bipyridine, or phenanthroline groups in their framework (see ... -
Synthesis of some 4-pyrrolylphenylthiazole derivatives and investigation of their antimicrobial activities
(1997)In this study, some 2-substituted 4-[4-(pyrrol-1-yl)phenyl] thiazole derivatives were obtained reacting some 1,4-dicarbonyl compounds and 2-substituted 4-(4-aminophenyl) thiazoles. The latters were prepared by hydrolyzing ... -
Synthesis of some 2-aryl-benzoxazole derivatives and investigation of their mutagenicity
(1995)In this study, eight of 2-aryl-benzoxazole derivatives have been synthesized. The comprehensive studies have not been found about spectral analyses of these compounds in the literature. For this reason, melting points of ... -
Synthesis of some 1-(2-arylvinyl)-3-arylpyrazino[1,2-a]benzimidazole derivatives and their antimicrobial activities
(1996)Some 1-(2-arylvinyl)-3-arylhyrazino[1,2-a]benzimidazole derivatives were synthesized, their structures were elucidated, and their antibacterial and antifungal activities were examined. None of the compounds proved to be ... -
Studies on the determination of the physicochemical parameters of some commercially available sulfonamide drugs in Turkey
(1995)[No abstract available] -
QSAR of inhibitory activities by 2-substituted-4,5-difuryl imidazole derivatives on tubifex worms
(1995)[No abstract available] -
Synthesis of some 5-methoxy-3-[(benzazole-2-yl)thioacetylamino]-2,3-dihydrobenzofuran derivatives and study of their antihypertensive activity [SYNTHESE DE CERTAINS DERIVES DE METHOXY-5 [(BENZAZOLE-2-YL)THIOACETYLAMINO]-3 DIHYDRO-2,3 BENZOFURANE ET RECHERCHE D'ACTIVITE ANTIHYPERTENSIVE]
(1994)In this study, some 5-methoxy-3-[(benzazole-2-yl) thioacetylamino]2,3-dihydrobenzofuran derivatives were synthesized and their structures were elucidated by IR, NMR and microanalyses. The antihypertensive activities of the ... -
QSAR of inhibitory activities by 2,4,5-trisubstituted imidazole derivatives on tubifex worms
(1995)[No abstract available] -
Synthesis and structure of derivatives of [?-(N-substituted aminothiocarbonylthio)acetyl] substituted phenols [SYNTHESE ET STRUCTURE DES DERIVES DE [?-(N-SUBSTITUES AMINOTHIOCARBONYLTHIO)ACETYL]-2 PHENOLS SUBSTITUES]
(1994)In this study, 2-[?-(N-substituted aminothiocarbonylthio)acetyl] substituted phenols were synthesized and their structures were elucidated by IR, NMR and elemental analyses. -
Production of ?-terpineol from ?-pinene
(1995)?-Terpineol is a monoterpene alcohol used as a fragrance material in perfumery industry and for the production of some volatile compounds. Several techniques have been described in the literature for its synthesis. These ...
