Yazar "Akalın Çiftçi, Gülsen" için Makale Koleksiyonu listeleme
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Apoptotic Effects of Some Thiohydantoin Derivatives
Seller, Zerrin; Akalın Çiftçi, Gülsen (Turkish Biochem Soc, 2010)Objectives: The aim of this study is to investigate the effects of newly synthesized 3-phenly-and 3-(4-methoxyphenyl)-2-thiohydantoin derivatives on 5RP7 ve CO25 cell apoptosis. Methods and Materials: Thiohydantoin derivatives ... -
Apoptotic effects of some thiohydantoin derivatives [Bazi{dotless} Tiyohidantoin Türevlerinin Apoptotik Etkileri]
Seller, Zerrin; Akalın Çiftçi, Gülsen (2010)Objectives: The aim of this study is to investigate the effects of newly synthesized 3-phenly-and 3-(4-methoxyphenyl)-2-thiohydantoin derivatives on 5RP7 ve CO25 cell apoptosis. Methods and Materials: Thiohydantoin derivatives ... -
The effects of 1,3 bis (heteroaryl substitued) benzene derivatives on apoptosis of N-ras transformed mouse skeletal muscle cell [1,3-Bi·s (heteroari·l sübsti·tüe) benzen türevleri·ni·n N-ras transform fare kasi hücre apoptozu üzeri·ne etki·leri·]
Akalın Çiftçi, Gülsen; Seller, Zerrin (2005)Increasing number of the cells, results of excess divicing of the cells, is balanced by apoptosis which causes elimination of old cells and unfunctional cells. Apoptosis is a programmed cell death obtaining this balance. ... -
The effects of atorvastatin on antioxidant/antiinfammatory properties of HDLs in hypercholesterolemics
Background/aim: Hypercholesterolemia is characterized by changes in lipid profle, nitric oxide pathway, and oxidative stress markers, but functions of high-density lipoprotein (HDL) were not well established in ... -
The effects of carvacrol on apoptosis of H-ras and N-ras transformed cell lines
Akalın Çiftçi, Gülsen; Seller, Zerrin (2011)Fenolik bir monoterpen olan karvakrol kekik bitkisinde bulunmaktadır ve besinlerde baharat olarak kullanılmaktadır. Bu çalışmanın amacı, karvakrol’ün H-ras transform edilmiş 5RP7 ve N-ras transform edilmiş CO25 hücreleri ... -
The effects of carvacrol on apoptosis of H-ras and N-ras transformed cell lines [Karvakrol'ün H-ras ve N-ras transform hücre apoptozu üzerine etkileri]
Akalın Çiftçi, Gülsen; Seller, Zerrin (2011)Carvacrol is a phenolic monoterpen found in Thyme plant which is used as a source of flavour in food. The aim of this study was to investigate apoptotic effects of carvacrol on H-ras transformed 5RP7 and N-ras transformed ... -
Synthesis and in vitro Biological Activity of New 4,6-Disubstituted 3(2H)-Pyridazinone-acetohydrazide Derivatives
Şüküroğlu, Murat; Onkol, Tijen; Onurdağ, Fatma Kaynak; Akalın Çiftçi, Gülsen; Şahin, M. Fethi (Verlag Z Naturforsch, 2012)New 3(2H)-pyridazinone derivatives containing a N'-benzyliden-acetohydrazide moiety at position 2 were synthesized. The structures of these newly synthesized compounds were confirmed by IR, H-1 NMR, and MS data. These ... -
Synthesis, characterization of some transition-metal complexes of a new heptadentate N(5)S(2) Schiff-base ligand and the effects of these metal complexes on U2OS cells cytotoxicity and DNA cleavage activity
Uluçam, G.; Beynek, Nesrin; Seller, Zerrin; Akalın Çiftçi, Gülsen; Turan, Gülhan; Benkli, Kadriye (Taylor & Francis LTD, 2008)Metal complexes of a heptadentate N(5)S(2) donor Schiff-base ligand were synthesized by the template reaction between 2,6-bis(2-aminothiophenoxymethyl)pyridine and 2,2 '-bipyridine-6,6'-dicarboxaldehyde in the presence of ... -
Towards Novel Anti-tumor Strategies for Hepatic Cancer: epsilon-Viniferin in Combination with Vincristine Displays Pharmacodynamic Synergy at Lower Doses in HepG2 Cells
Özdemir, Filiz; Akalın Çiftçi, Gülsen; Sen, Mesut; Önder, Nur İpek; İşcan, Arzu; Kutlu, Hatice Mehtap; Seller, Zerrin (Mary Ann Liebert, Inc, 2014)Hepatocellular carcinoma is the fifth most common cancer and the third leading cause of cancer-related deaths worldwide. The efficacy of novel combination treatments are increasingly evaluated with use of integrative biology ...