| dc.contributor.author | Karatoprak, Gokce Seker | |
| dc.contributor.author | Pasayeva, Leyla | |
| dc.contributor.author | Safak, Esra Kongul | |
| dc.contributor.author | Goger, Fatih | |
| dc.contributor.author | Tugay, Osman | |
| dc.contributor.author | Kosar, Muberra | |
| dc.date.accessioned | 2020-07-09T20:58:55Z | |
| dc.date.available | 2020-07-09T20:58:55Z | |
| dc.date.issued | 2019 | |
| dc.identifier.issn | 0014-8237 | |
| dc.identifier.issn | 2065-0019 | |
| dc.identifier.uri | https://doi.org/10.31925/farmacia.2019.6.17 | |
| dc.identifier.uri | https://hdl.handle.net/11421/24098 | |
| dc.description | Karatoprak, Gokce Seker/0000-0001-5829-6914; Pasayeva, Leyla/0000-0003-3860-7222; KONGUL SAFAK, ESRA/0000-0003-4775-6860 | en_US |
| dc.description | WOS: 000510208600017 | en_US |
| dc.description.abstract | Aerial part extracts of Kitaibelia balansae Boiss. were examined for their phenolic contents, as well as anti-inflammatory activities. the chemical compositions of the extracts were analysed by spectrophotometric and chromatographic (HPLC/ MS/MS and HPLC-PDA) approaches. To measure anti-inflammatory activity, the effects of the extracts on nitric oxide (NO) and Tumour Necrosis Factor-alpha (TNF-alpha) levels were measured in lipopolysaccharide (LPS) treated murine macrophage cell line (RAW 264.7). the ethyl acetate fraction was found to be abundant in phenolic compounds (259.78 +/- 15.07 mg(GAE)/gextract). Rutin was identified as the major compound in all the extracts. the ethyl acetate fraction potentially inhibited NO and TNF-alpha production (37.26 mu M and 1781.524 pg/mL, respectively, 6 h) in LPS induced cells. | en_US |
| dc.description.sponsorship | Erciyes University Scientific Research ProjectsErciyes University [THD-2016-6600] | en_US |
| dc.description.sponsorship | Erciyes University Scientific Research Projects (THD-2016-6600) supported this research. | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | Soc Stiinte Farmaceutice Romania | en_US |
| dc.relation.isversionof | 10.31925/farmacia.2019.6.17 | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Kitaibelia balansae | en_US |
| dc.subject | Malvaceae | en_US |
| dc.subject | HPLC/MS/MS | en_US |
| dc.subject | anti-inflammatory | en_US |
| dc.title | CHEMICAL COMPOSITION AND ANTI-INFLAMMATORY ACTIVITY OF KITAIBELIA BALANSAE BOISS | en_US |
| dc.type | article | en_US |
| dc.relation.journal | Farmacia | en_US |
| dc.contributor.department | Anadolu Üniversitesi | en_US |
| dc.identifier.volume | 67 | en_US |
| dc.identifier.issue | 6 | en_US |
| dc.identifier.startpage | 1054 | en_US |
| dc.identifier.endpage | 1059 | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
