In vitro antimicrobial evaulation of Ferulago Sandrasica Pe?men & Quézel Herba and root essential oil

Abstract

Ferulago sandrasica Pe?men & Quézel was initially collected from Köyceğiz, which is endemic species for Turkey. The air dried herbal parts and roots were evaluated for their volatile compositions and antimicrobial activity. The essential oils were obtained by hydrodistillation, which were subsequently analyzed by GC-FID and GC-MS, respectively. The main components of the herb essential oil were identified as ?-pinene (26.4%), caryophyllene oxide (6.1%), camphene (5.1%), trans-verbenol (5%); whereas the root essential oil compounds were ?-pinene (27.9%), limonene (26.1%), ?-3-carene (14.2%), myrcene (7.6%), terpinolene (11%), respectively. In addition, the essential oils were evaluated for their in vitro antimicrobial activity using a broth microdilution method against the human pathogens Escherichia coli, Staphylococcus aureus, Salmonella typhimurium, Bacillus subtilis, and the yeasts Candida tropicalis, C. parapsilosis. The activity results showed that F. sandrasica was effective against the tested pathogens with the minimum inhibition concentrations (MIC) of 2.5-10 mg/mL. © 2019, Badebio Biotechnololgy Ltd. All rights reserved.