Güncel Gönderiler: PubMed İndeksli Yayınlar Koleksiyonu
Toplam kayıt 1498, listelenen: 841-860
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Cyclosporine-A incorporated cationic solid lipid nanoparticles for ocular delivery
(Taylor & Francis LTD, 2010)In the present study, Cyclosporine A (CsA) was successfully incorporated into cationic solid lipid nanoparticles (SLN) for ocular application. Physicochemical characterizations of SLNs were analysed in detail during the ... -
Polymeric Cyclosporine-A Nanoparticles for Ocular Application
(Amer Scientific Publishers, 2011)In the present study, cyclosporine A (CsA) was incorporated successfully into cationic Eudragit(R) RS 100 nanoparticles (EPNs) aiming ocular application. Physicochemical characterization of the EPNs prepared was performed ... -
Synthesis, molecular docking analysis and carbonic anhydrase I-II inhibitory evaluation of new sulfonamide derivatives
(NLM (Medline), 2019)New sulfonamide-hydrazone derivatives (3a-3n) were synthesized to evaluate their inhibitory effects on purified human carbonic anhydrase (hCA) I and II. The inhibition profiles of the synthesized compounds on hCA I-II ... -
Synthesis of some imidazolyl-thioacetyl-pyrazolinone derivatives and their antinociceptive and anticancer activitiesal
(2010)In this study, some 4-(1,5-diarylimidazol-2-yl)thioacetyl-1-phenyl-2,3- dimethyl-3-pyrazoline-5-one derivatives were prepared by reacting 4-(2-chloroacetyl)-1-phenyl-2,3-dimethyl-3-pyrazoline-5-one and 2-mercapto-1, ... -
Synthesis and cytotoxic and analgesic activities of some 1, 5-diaryl-3-ethoxycarbonylpyrrole derivatives
(2006)Some 1,5-diaryl-3-ethoxycarbonyl-2-methylpyrrole derivatives were obtained by reacting 1-aryl-3-ethoxycarbonylpent-1,4-diones and a suitable aniline derivative or sulfanilamide under Paal-Knorr pyrrole synthesis conditions. ... -
Synthesis of some 1-(2-arylvinyl)-3-arylpyrazino[1,2-a]benzimidazole derivatives and their antimicrobial activities
(1996)Some 1-(2-arylvinyl)-3-arylhyrazino[1,2-a]benzimidazole derivatives were synthesized, their structures were elucidated, and their antibacterial and antifungal activities were examined. None of the compounds proved to be ... -
Synthesis of some 5-methoxy-3-[(benzazole-2-yl)thioacetylamino]-2,3-dihydrobenzofuran derivatives and study of their antihypertensive activity [SYNTHESE DE CERTAINS DERIVES DE METHOXY-5 [(BENZAZOLE-2-YL)THIOACETYLAMINO]-3 DIHYDRO-2,3 BENZOFURANE ET RECHERCHE D'ACTIVITE ANTIHYPERTENSIVE]
(1994)In this study, some 5-methoxy-3-[(benzazole-2-yl) thioacetylamino]2,3-dihydrobenzofuran derivatives were synthesized and their structures were elucidated by IR, NMR and microanalyses. The antihypertensive activities of the ... -
Synthesis and antimicrobial activities of some 3-arylamino-5-[2-(substituted 1-imidazolyl)ethyl]-1,2,4-triazole derivatives
(Elsevier Masson SAS, 2000)In this study, some 3-arylamino-5-[2-(substituted imidazol-1-yl or benzimidazol-1-yl)ethyl]-1,2,4-triazole derivatives were synthesised by reacting 3-(substituted imidazol-1-yl)propionyl hydrazides, with S-methyl-N'-aryl ... -
Synthesis and analgesic activities of 2-substituted-1H-phenantro [9,10- d] imidazoles
(1999)Some 2-substituted-1H-phenantro [9, 10-d] imidazole compounds were synthesized and their analgesic activities were determined on the Swiss albino mice (25-35 g) of either sex. In the synthesis, phenantrenequinone molecule ... -
Syntheses and analgesic activities of some 2-substituted-4,5-diphenyl and 1,2-disubstituted-4,5-diphenyl imidazole derivatives
(1999)Some substituted imidazole compounds were synthesized and their analgesic activities were determined on the Swiss albino mice (25-35 g) of either sex. During the synthesis, 2-substituted-4,5-diphenyl imidazole compounds ... -
Synthesis of some 3-arylamino-5-aryloxymethyl[1,2,4]triazole derivatives and their antimicrobial activity
(1998)In this study, some 3-arylamino-5-aryloxymethyl[1,2,4]triazole derivatives were synthesized by reacting S-methyl-N'-arylisothiouronium iodide and 2- (aryloxy)alkanoic acid hydrazide. The structural elucidation of the ... -
Some 1-substituted 3-aryl-1,4-dihydro-1,2,4-triazino[4,3-a]- benzimidazoles and their vasodilatory activities
(Societa Chimica Italiana, 1997)In this study, some 1-substituted 3-aryl-1,4-dihydro-1,2,4- triazino[4,3-a]benzimidazole derivatives were synthesized, their structures were elucidated, and their vasodilatory activities were examined. It was found that ... -
N-(chroman-4-ylidene)aryloxyacetohydrazones: Synthesis and antimicrobial activity
(1997)In this study, some N-(chroman-4-ylidene)phenoxyacetohydrazone and N-(chroman-4-ylidene)phenoxypropiohydrazone compounds were synthesized. Structure of the compounds were identified by using IR, 1H NMR and MASS spectral ... -
Synthesis and antimicrobial activity of some imidazo-[1,2-a]pyridine-2-carboxylic acid arylidenehydrazide derivatives
(2001)Imidazo[1,2-a]pyridine-2-carboxylic acid, ethyl esters were reacted with hydrazine hydrate to furnish imidazo[1,2-a]pyridine-2-carboxylic acid hydrazide. The hydrazides formed were treated with various aldehydes to obtain ... -
Synthesis and analgesic activity of some 1-benzyl-2-substituted-4,5-diphenyl-1H-imidazole derivatives
(2001)In this study, derivatives of 1-benzyl-2-substituted-4,5-diphenyl-1H-imidazole were synthesized and their analgesic activity assayed in two tests. 1,2,4,5-Tetrasubstituted imidazole compounds were obtained by the treatment ... -
Synthesis and anticancer and anti-HIV testing of some pyrazino[1,2-a]benzimidazole derivatives
(2002)In this study, some 1-methylene-2,3-diaryl-1,2-dihydropyrazino[1,2-a]benzimidazole and some 1-(2-arylvinyl)-3-arylpyrazino[1,2-a]benzimidazole derivatives were synthesised. The structure elucidation of the compounds was ... -
Synthesis and effects on intracellular calcium of some 1,3-bis-(heteroaryl substituted)benzene derivatives
(2002)A series of 1,3-bis-(heteroaryl substituted)benzene derivatives was designed as promising molecules which might increase intracellular Ca2+ level in F2408 fibroblast-like cells by affecting the Ca2+ channels on plasma ... -
Synthesis and antimicrobial activity of some pyridinyliminothiazoline derivatives
(2002)The synthesis of some pyridinyliminothiazoline derivatives starting from N-pyridine-N'-phenyl thiourea and ?-halogenoacetophenones is described. The chemical structures of the compounds were elucidated. The prepared compounds ... -
The synthesis of some triazolylphenothiazine derivatives and their antidepressant and anxiolytic activities
(2002)10-[2-(4-Amino-5-mercapto-1,2,4-triazol-3-yl)ethyl]phenothiazine was prepared starting from 3-(10-phenothiaziniyl)propionic acid. This new triazole was employed in the synthesis of some Schiff bases and N-bridged heterocycles. ... -
Some pyrrole substituted aryl pyridazinone and phthalazinone derivatives and their antihypertensive activities
(2004)In this work, some 2-nonsubstituted/2-methyl-/2-(2-acetyloxyethyl)-6-[4- (substituted pyrrol-1-yl)phenyl]-4,5-dihydro-3(2H)-pyridazinone, derivatives and 2-nonsubstituted/2-methyl- 4-[4-(substituted pyrrol-1-yl)phenyl]-1(2H)- ...
