Konu "Cytotoxicity" için PubMed İndeksli Yayınlar Koleksiyonu listeleme
Toplam kayıt 57, listelenen: 1-20
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Acrylamide exerts its cytotoxicity in NIH/3T3 fibroblast cells by apoptosis
(Sage Publications Inc, 2018)Objective: Acrylamide is a chemical utilized in various industries, and many studies have demonstrated its toxicity. The NIH/3T3 mouse embryonic cell line is the standard cell line of fibroblasts, which have a pivotal role ... -
Acrylamide-derived cytotoxic, anti-proliferative, and apoptotic effects on A549 cells
(SAGE Publications LTD, 2018)Background: Acrylamide is a very common compound even reaching up to our daily foods. It has been studied in a wealth of cell lines on which it proved to have various toxic effects. Among these cell lines, human lung ... -
Analyses of the modulatory effects of antibacterial silver doped calcium phosphate-based ceramic nano-powder on proliferation, survival, and angiogenic capacity of different mammalian cells in vitro
(IOP Publishing LTD, 2015)In this study, the antibacterial, cytotoxic, and angiogenic activities of silver doped calcium phosphate-based inorganic powder (ABT or PAG) were systematically investigated. ABT powders containing varying silver content ... -
Antibacterial profiling of abietane-type diterpenoids
(Pergamon-Elsevier Science LTD, 2017)Abietic and dehydroabietic acid are interesting diterpenes with a highly diverse repertoire of associated bioactivities. They have, among others, shown antibacterial and antifungal activity, potentially valuable in the ... -
Antimicrobial and Cytotoxic Evaluation of New Quinazoline Derivatives
(Natural Products Inc, 2016)The synthesis of nine new quinazoline derivatives (2a-21) and evaluation of their antimicrobial and cytotoxic activities were aims of the present work. For the synthesis of the compounds, 2-chloro-6,7-dimethoxyquinazolin-4-amine ... -
Assessment of Aprotinin Loaded Microemulsion Formulations for Parenteral Drug Delivery: Preparation, Characterization, in vitro Release and Cytotoxicity Studies
(Bentham Science Publ LTD, 2016)The object of the current study was to prepare novel microemulsion formulations of aprotinin for parenteral delivery and to compare in vitro characteristics and release behaviour of different Technetium-99m (Tc-99m)-Aprotinin ... -
Assessment of in vitro cytotoxic and genotoxic activities of some trimethoprim conjugates
(Springer, 2018)Trimethoprim, a commonly used antibacterial agent, is widely applied in the treatment of variety of infections in human. A few studies have demonstrated an extensive exposure of man to antibiotics, but there is still a ... -
Bioassay-Guided Investigation of Two Monarda Essential Oils as Repellents of Yellow Fever Mosquito Aedes aegypti
(American Chemical Society, 2013)As part of an ongoing research program to identify active mosquito repellents, Monarda bradburiana Beck and Monarda fistulosa L. essential oils showed good repellent activity with minimum effective dosages (MED) of 0.055 ... -
Biocompatibility of designed MicNo-ZnO particles: Cytotoxicity, genotoxicity and phototoxicity in human skin keratinocyte cells
(Pergamon-Elsevier Science LTD, 2018)Recently, designed platelet shaped micron particles that are composed of nano primary particles, called MicNo (= Micron + naNo) particles, have been developed to exploit the benefits of nano size, while removing the adverse ... -
Biological assays on the effects of Acra3 peptide from Turkish scorpion Androctonus crassicauda venom on a mouse brain tumor cell line (BC3H1) and production of specific monoclonal antibodies
(Pergamon-Elsevier Science LTD, 2013)Constitutes of the venom scorpion are a rich source of low molecular mass peptides which are toxic to various organisms, including man. Androctonus crassicauda is one of the scorpions from the Southeastern Anatolia of ... -
Characterization of Leiurus abdullahbayrami (Scorpiones: Buthidae) venom: peptide profile, cytotoxicity and antimicrobial activity
(Biomed Central LTD, 2014)Background: Scorpion venoms are rich bioactive peptide libraries that offer promising molecules that may lead to the discovery and development of new drugs. Leiurus abdullahbayrami produces one of the most potent venoms ... -
Composition, antimicrobial activity and in vitro cytotoxicity of essential oil from Cinnamomum zeylanicum Blume (Lauraceae)
(Pergamon-Elsevier Science LTD, 2010)The essential oil from the bark of Cinnamomum zeylanicum Blume was analyzed by GC-MS and bioassays were carried out. Nine constituents representing 99.24% of the oil were identified by GC-MS. The major compounds in the oil ... -
Cytotoxic, anti-proliferative and apoptotic effects of silver nitrate against H-ras transformed 5RP7
(Springer, 2016)Metal based drugs have successfully been used in both the detection and treatment of different disease states. The antibacterial features of metal ion silver are well documented. Most recently, metal ion silver has been ... -
Cytotoxic, Antiproliferative and Apoptotic Effects of New Benzimidazole Derivatives on A549 Lung Carcinoma and C6 Glioma Cell Lines
(Bentham Science Publ LTD, 2015)Benzimidazole ring is a versatile structure which has been extensively utilized in medicinal chemistry. Since we are working on 1,2-disubstutited benzimidazoles, we have reported new antitumor active derivatives. As a ... -
Cytotoxic, Antiproliferative and Apoptotic Effects of Perillyl Alcohol and Its Biotransformation Metabolite on A549 and HepG2 Cancer Cell Lines
(Bentham Science Publ LTD, 2017)Background: A monoterpene, perillyl alcohol, has attracted attention in medicinal chemistry since it exhibited chemo-preventive and therapeutic properties against a variety of cancers. Objective: In the present work, it ... -
Cytotoxicity of naturally occurring phenolics and terpenoids from Kenyan flora towards human carcinoma cells
(Elsevier, 2019)Background: Cancer constitutes a major hurdle worldwide and its treatment mainly relies on chemotherapy. Objectives: the present study was designed to evaluate the cytotoxicity of eleven naturally occurring compounds ... -
Cytotoxicity of Plumbagin, Rapanone and 12 other naturally occurring Quinones from Kenyan Flora towards human carcinoma cells
(Bmc, 2016)Background: Cancer is a major public health concern globally and chemotherapy remains the principal mode of the treatment of various malignant diseases. Methods: This study was designed to investigate the cytotoxicity of ... -
Cytotoxicity of seputhecarpan D, thonningiol and 12 other phytochemicals from African flora towards human carcinoma cells
(Bmc, 2018)Background: Despite the remarkable progress in cancer therapy in recent years, this disease still remains a serious public health concern. The use of natural products has been and continues to be one of the most effective ... -
Cytotoxicity of the methanol extracts of Elephantopus mollis, Kalanchoe crenata and 4 other Cameroonian medicinal plants towards human carcinoma cells
(Bmc, 2017)Background: Cancer still constitutes one of the major health concerns globally, causing serious threats on patients, their families, and the healthcare system. Methods: In this study, the cytotoxicity of the methanol extract ... -
Design and Synthesis of New Benzothiazole Compounds as Selective hMAO-B Inhibitors
(MDPI AG, 2017)In the current work a new class of novel benzothiazole-hydrazone derivatives was designed and synthesized as hMAO-B inhibitors. Structures of the obtained compounds (3a-3j) were characterized by IR, 1H-NMR, 13C-NMR, and ...