Başlık için PubMed İndeksli Yayınlar Koleksiyonu listeleme
Toplam kayıt 1498, listelenen: 745-764
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In silico Molecular Docking and ADME Studies of 1 3,4-Thiadiazole Derivatives in Relation to in vitro PON1 Activity
(Bentham Science Publ LTD, 2019)Background: Paraoxonase 1 (PON1) is a paraoxonase, arylesterase and lactonase associated with protection of lipoproteins and cell membranes against oxidative modification. Objective: Based on antioxidative properties of ... -
In situ electrochemical solid-phase extraction of anions and cations using polypyrrole and overoxidized sulfonated polypyrrole
(Elsevier Science BV, 2008)A new method for the extraction of both anions and cations is proposed using electro-synthesized polypyrrole (PPy) and overoxidized sulfonated polypyrrole film (OSPPy). In situ anion (chloride, nitrate, sulfate) and cation ... -
In vitro and in silico evaluation of new thiazole compounds as monoamine oxidase inhibitors
(Academic Press Inc Elsevier Science, 2019)New twenty compounds bearing thiazole ring (3a-3t) were designed and synthesized as monoamine oxidase (MAO) inhibitors. The fluorometric enzyme inhibition assay was used to determine the biological effects of synthesized ... -
In vitro antibacterial and antibiotic modifying activity of crude extract, fractions and 3 ', 4 ', 7-trihydroxyflavone from Myristica fragrans Houtt against MDR Gram-negative enteric bacteria
(Biomed Central LTD, 2018)Background: Nutmeg is the seed kernel inside the fruit of Myristica fragrans Houtt. (Myristicaceae). It possesses various pharmacological activities but is used in Cameroon only for its flavor in making cakes. The present ... -
In vitro antioxidant properties and anthocyanin compositions of elderberry extracts
(Elsevier Sci LTD, 2014)In this study, dried elderberry fruits growing wild in Turkey were macerated using different solvents and an infusion was prepared according to traditional methods. All extracts were investigated for their total phenolic ... -
In vitro antioxidant properties and phenolic composition of Salvia halophila Hedge from Turkey
(Elsevier Sci LTD, 2011)An endemic plant of Turkey Salvia halophila Hedge (Lamiaceae) was examined for its antioxidant activity and phenolic compositions. The aerial part of S. halophila was extracted with different solvents in an order of ... -
In vitro antioxidant properties and phenolic composition of Salvia virgata Jacq. from Turkey
(American Chemical Society, 2008)Antioxidant activities and phenolic compositions of the active fractions of Salvia virgata Jacq. (Lamiaceae) from Turkey were examined. The aerial part of S. virgata was extracted with different solvents in an order of ... -
In vitro antitumor activity evaluation of some 1,2,4-triazine derivatives bearing piperazine amide moiety against breast cancer cells
(Pergamon-Elsevier Science LTD, 2014)A series of 1,2,4-triazine derivatives bearing piperazine amide moiety has been synthesized and investigated for their potential anticancer activities. 1-[4-(5,6-Bis(4-subtituted phenyl)-1,2,4-triazin-3-yl) piperazin- ... -
The in vitro assessment of dipyridophenazine complexes in H-ras oncogene transformed rat embryo fibroblast 5RP7 cell line
(Springer, 2018)Purpose The aim of this study is to detect apoptotic and cytotoxic/antiproliferative effects of a ligand substance and its metal derivatives. The substances were investigated by using an h-ras oncogene transformed rat ... -
In vitro biological activity and essential oil composition of four indigenous South African Helichrysum species
(Elsevier Sci Ireland LTD, 2004)Helichrysum species are used widely to treat various medical conditions. In this study, the anti-microbial, anti-oxidant (DPPH assay) and anti-inflammatory activity (5-lipoxygenase assay) of Helichrysum dasyanthum, Helichrysum ... -
In vitro cytotoxic activities of (+)-usnic acid and (-)-usnic acid on V79, A549, and human lymphocyte cells and their non-genotoxicity on human lymphocytes
(Taylor & Francis LTD, 2006)This study investigates cytotoxic and genotoxic activities of (+)-Usnic acid and (-)-usnic acid isolated from the lichen Ramalina farinacea and the lichen Cladonia foliacea, respectively. To determine the activities of ... -
In vitro evaluation of combination of EGCG and Erlotinib with classical chemotherapeutics on JAR cells
(Springer, 2017)Gestational Trophoblastic Neoplasia (GTN) is a term used for a group of malignant gynecological tumors including choriocarcinoma. Low-risk neoplasias can be cured using single agents Methotrexate (MTX) and actinomycin-D(ACD), ... -
In vitro genotoxic and cytotoxic effects of some paraben esters on human peripheral lymphocytes
(Taylor & Francis LTD, 2019)Parabens (PBs) are p-hydroxybenzoic acid ester compounds commonly employed as antimicrobial preservatives, mainly in food, cosmetic, and pharmaceutical products. The aim of the present study was to investigate the genotoxic ... -
An in vitro investigation of genotoxic effects of dexketoprofen trometamol on healthy human lymphocytes
(Taylor & Francis Ltd, 2020)Non-steroidal anti-inflammatory drugs are drugs with analgesic, antipyretic, and anti-inflammatory effects. This study uses in vitro methods to investigate the potential and unknown genotoxic effects of dexketoprofen ... -
The in vitro pharmacological activities and a chemical investigation of three South African Salvia species
(Elsevier Ireland LTD, 2005)Salvia species (sage) are well known in folk medicine throughout the world. In South Africa sage is used against fever and digestive disorders. Three closely related South African species (Salvia stenophylla, Salvia repens ... -
In vitro/in vivo evaluation of gamma-aminobutyric acid-loaded N,N-dimethylacrylamide-based pegylated polymeric nanoparticles for brain delivery to treat epilepsy
(Taylor & Francis LTD, 2016)Objectives of this study were the delivery of gamma aminobutyric acid (GABA) into the brain by means of developing brain targeted, nanosized, non-toxic and biocompatible polymeric nanoparticles, and investigating their ... -
An in vivo database model for pharmacological and physiological dosage for experimental animals
(Pergamon-Elsevier Science LTD, 2009)We developed a database compiling in vivo doses of compounds for various activities in certain animal species. The related database covers almost 100 years of experiments. The conceptual scheme of the database was created ... -
The in vivo evaluation of anti-angiogenic effects of Hypericum essential oils using the chorioallantoic membrane assay
(Taylor & Francis LTD, 2014)Context: Hypericum species including Hypericum confertum Choisy, H. hircinum L., H. hyssopifolium Chaix. subsp. elongatum (Ledeb.) Woron var. microcalycinum (Boiss. & Heldr.) Boiss. and H. perforatum L. (Clusiaceae) are ... -
In Vivo Wound Healing and In Vitro Anti-Inflammatory Activity Evaluation of Phlomis russeliana Extract Gel Formulations
(NLM (Medline), 2020)The air-dried aerial parts of Phlomis russeliana (Sims) Lag. Ex Benth. was extracted by methanol and fractionated by n-hexane, dichloromethane, and ethyl acetate, respectively. The wound healing properties of P. russeliana ... -
Increased Alpha(1)-Adrenergic Responsiveness of Alloxan-Diabetic Rat Atria - Effects of Insulin Therapy and Thyroidectomy
(Pergamon-Elsevier Science LTD, 1994)1. Experimental models of diabetes are increasingly used for the investigation of cardiovascular complications as well as other complications due to diabetes mellitus. However, animal models have been used in relatively ...
