Bölüm "Anadolu Üniversitesi" PubMed İndeksli Yayınlar Koleksiyonu için listeleme
Toplam kayıt 128, listelenen: 21-40
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Catecholaminergic and opioidergic system mediated effects of reboxetine on diabetic neuropathic pain
(Springer, 2020)Rationale Current data indicate that the noradrenergic system plays a critical role in neuropathic pain treatment. Notably, drugs that directly affect this system may have curative potential in neuropathy-associated pain. ... -
Chemical Characterization and Biological Activity of the Mastic Gum Essential Oils of Pistacia lentiscus var. chia from Turkey
(Mdpi, 2020)The essential oils (EOs) were isolated by hydrodistillation from wild and cultivated Pistacia lentiscus L. var. chia-mastic gum tree (Anacardiaceae) from two natural habitats, namely from Cesme-Uzunkoy (1) and Mordogan ... -
Chemical composition and antioxidant, cytotoxic, and insecticidal potential of Valeriana alliariifolia in Turkey
(Inst Medical Research & Occupational Health, 2019)Valeriana is a common plant species used for various healing purposes in folk medicine since antiquity. This study investigates the phytochemical profile, antioxidant, cytotoxic, and insecticidal activity of Valeriana ... -
Chemical composition and immunomodulatory activity of hypericum perforatum essential oils
(MDPI AG, 2020)Hypericum L. (Hypericaceae) extracts have been used for their therapeutic effects; however, not much is known about the immunomodulatory activity of essential oils extracted from this plant. We isolated essential oils from ... -
Clarithromycin-Loaded Poly (Lactic-co-glycolic Acid) (PLGA) Nanoparticles for Oral Administration: Effect of Polymer Molecular Weight and Surface Modification with Chitosan on Formulation, Nanoparticle Characterization and Antibacterial Effects
(Mdpi, 2019)Clarithromycin (CLR) is a member of the macrolide antibiotic group. CLR has low systemic oral bioavailability and is a drug of class II of the Biopharmaceutical Classification System. in many studies, using nanoparticles ... -
Comment on: "clinical relevance of insulin-like growth factor-1 to cardiovascular risk markers"
(Taylor & Francis Ltd, 2020)… -
Cytotoxicity of naturally occurring phenolics and terpenoids from Kenyan flora towards human carcinoma cells
(Elsevier, 2019)Background: Cancer constitutes a major hurdle worldwide and its treatment mainly relies on chemotherapy. Objectives: the present study was designed to evaluate the cytotoxicity of eleven naturally occurring compounds ... -
Decreased gastro-intestinal responses to salbutamol and serotonin in streptozotocin-induced diabetes: Improving effect of insulin in vivo and in vitro
(1988)1. 1. Decreased gastro-intestinal responses to salbutamol (sal) and serotonin (5-HT) in experimental diabetes have been postulated. The present study was designed to investigate whether in vivo and in vitro insulin treatments ... -
The Determination of Ofloxacin in Tablets By Potentiometry and Conductometry
(Govi-Verlag GMBH, 1992)… -
Development of a RP-HPLC method for simultaneous determination of reference markers used for in-situ rat intestinal permeability studies
(Elsevier, 2020)One of the most common techniques for assessing the intestinal absorption characteristics of drugs is single-pass intestinal perfusion (SPIP) method. Metoprolol tartrate (MT, reference standard) and phenol red (PR, zero ... -
Diclofenac sodium loaded PLGA nanoparticles for inflammatory diseases with high anti-inflammatory properties at low dose: Formulation, characterization and in vivo HET-CAM analysis
(Academic Press Inc Elsevier Science, 2020)The development of a new drug active substance is not only time-consuming and expensive, but also a chain of operations that often fails. However, increasing the bioavailability, effectiveness, safety, or targeting the ... -
Duration-dependent changes in calcium responsiveness in the alloxan-diabetic rat intestine
(Elsevier Science Inc, 1996)Disturbances of the gastrointestinal tract that are common in diabetes mellitus seem to be related to intestinal motility. In experimental models of diabetes, decreased calcium sensitivity has been demonstrated in various ... -
Education of Speech and Language Therapists/Logopedists in Selected Central and Southeastern European Countries: Challenges and New Horizons
(Karger, 2014)Objective: To provide an overview of student training in speech and language therapy/logopedics (SLT) in selected Central and Southeastern European countries (Poland, Slovenia, Bulgaria, Czech Republic, Serbia, Bosnia and ... -
Effect of different molecular weight PLGA on flurbiprofen nanoparticles: formulation, characterization, cytotoxicity, and in vivo anti-inflammatory effect by using HET-CAM assay
(Taylor & Francis Ltd, 2020)Objective: the effect of polymers used in nanoparticle (NP) production on the formulation properties is one of the few studied issues. Therefore, this study aims to formulate flurbiprofen (FLB) loaded NPs with different ... -
Effect of Insulin on the Decreased Beta-Adrenergic Responses of Duodenum and Atrium Isolated From Streptozotocin Diabetic Rats
(Pergamon-Elsevier Science LTD, 1993)1. Decreased beta-adrenergic responses have been reported in both gastro-intestinal tract and atrium of experimentally-induced diabetic rats. The present study was undertaken to investigate in vitro effects of insulin on ... -
Effect of insulin treatment on smooth muscle calmodulin levels in rats with long-term streptozotocin-diabetes
(Elsevier Sci Ireland LTD, 1996)Altered responses to several agonists have been reported in various smooth muscles from experimentally-diabetic animals suggesting a defective contractile process of smooth muscle Recently, decreased smooth muscle calmodulin ... -
The effect of R547, a cyclin-dependent kinase inhibitor, on hepatocellular carcinoma cell death
(Tubitak Scientific & Technical Research Council Turkey, 2020)Hepatocellular carcinoma (HCC) is the third main cause of cancer-related death. Cyclin-dependent kinases (CDKs) and their cyclin partners regulate the cell cycle. Since inhibition of CDKs gives some guiding ideas for cancer ... -
Effect of Short and Long-Term Streptozotocin Diabetes on Smooth-Muscle Calmodulin Levels in the Rat
(Churchill Livingstone, 1994)Diabetes mellitus is a metabolic disease associated with certain complications which have also been demonstrated in the experimental models of this disease. Altered responses to several agonists have been reported in various ...