Güncel Gönderiler: Eczacılık Fakültesi
Toplam kayıt 1731, listelenen: 501-520
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Synthesis and evaluation of new thiadiazole derivatives as potential inhibitors of human carbonic anhydrase isozymes (hCA-I and hCA-II)
(Informa Healthcare, 2015)2-[[5-(2,4-Difluoro/dichlorophenylamino)-1,3,4-thiadiazol-2-yl]thio] acetophenone derivatives (3a-s) were designed as human carbonic anhydrase isozymes (hCA-I and hCA-II) inhibitors and synthesized. hCA-I and hCA-II were ... -
Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Antinociceptive Agents
(MDPI AG, 2016)In the current work, new 1,3,4-thiadiazole derivatives were synthesized and investigated for their antinociceptive effects on nociceptive pathways of nervous system. The effects of these compounds against mechanical, thermal ... -
Synthesis of Some Novel Triazole Derivatives and Investigation of Their Antimicrobial Activities
(Taylor & Francis Inc, 2011)[image omitted] The aim of this study is to synthesize new triazole derivatives and investigate their antimicrobial activities. 4-Amino-5-(2-cyclohexylethyl)-3-[N-(benzothiazole-2-yl)acetamido]thio-4H-1,2,4-triazole and ... -
Synthesis and anticandidal activity of new triazolothiadiazine derivatives
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2011)New triazolothiadiazine derivatives were synthesized via the ring closure reaction of 4-amino-5-substituted-2,4-dihydro-3H-1,2,4-triazol-3-thiones with phenacyl bromides. The compounds were tested in vitro against various ... -
Synthesis and Anticholinesterase Activity and Cytotoxicity of Novel Amide Derivatives
(Wiley-V C H Verlag GMBH, 2012)In the present study, some amide derivatives were synthesized and their potential anticholinesterase properties were investigated. N-(Benzothiazol-2-yl)-2-[(5-amino/methyl-1,3,4-thiadiazol-2-yl)thio]acetamide derivatives ... -
Synthesis and Mosquitocidal Activity of a Series of Hydrazone Derivatives against Aedes aegypti
(Bentham Science Publ LTD, 2018)Background: Aedes aegypti is an important mosquito vector for the transmission of several infectious diseases. Current insecticides play a vital role in controlling mosquitoes; however, the frequent use of insecticides has ... -
Synthesis and Evaluation of a Series of 1,3,4-Thiadiazole Derivatives as Potential Anticancer Agents
(Bentham Science Publ LTD, 2018)Background and Methods: In an attempt to develop potent antitumor agents, the synthesis of a series of N-(6-substituted benzothiazol-2-yl)-2-1(5-(arylamino)-1,3,4-thiadiazol-2-yl)thiolacetamides (1-14) was described and ... -
Synthesis and Biological Evaluation of Some Pyrazoline Derivatives Bearing a Dithiocarbamate Moiety as New Cholinesterase Inhibitors
(Wiley-V C H Verlag GMBH, 2013)In the present study, new pyrazoline derivatives were synthesized via the reaction of 1-(chloroacetyl)-3-(2-furyl)-5-aryl-2-pyrazolines with sodium salts of N,N-disubstituted dithiocarbamic acids. Each derivative was ... -
Novel imidazole derivatives as antifungal agents: Synthesis, biological evaluation, ADME prediction and molecular docking studies
(Taylor & Francis LTD, 2019)A series of 2-(substituteddithiocarbamoyl)-N-[4-((1H-imidazol-1-yl)methyl)phenyl]acetamide derivatives was designed and synthesized to combat the increasing incidence of drug-resistant fungal infections. All synthesized ... -
Design, synthesis, in vitro and in silico evaluation of new pyrrole derivatives as monoamine oxidase inhibitors
(Wiley-V C H Verlag GMBH, 2018)In an effort to develop potent monoamine oxidase (MAO) inhibitors, new pyrrole derivatives were obtained via the selective reduction of the CC bonds of 1-(1-methyl-1H-pyrrol-2-yl)-3-[5-(aryl)furan-2-yl]prop-2-en-1-ones ... -
Synthesis and Biological Evaluation of a Series of Dithiocarbamates as New Cholinesterase Inhibitors
(Wiley-V C H Verlag GMBH, 2013)In the present paper, a novel series of dithiocarbamates was synthesized via the treatment of 4-(trifluoromethyl)benzyl chloride with appropriate sodium salts of N,N-disubstituted dithiocarbamic acids. H-1 NMR, mass spectral ... -
Oltu (Erzurum) yöresinde halk ilacı olarak kullanılan tıbbi bitkiler
(2015)Bu çalışma Erzurum ili, Oltu ve yöresinde geleneksel halk ilacı olarak kullanılan bitkileri ortaya çıkarmak amacıyla yapılmıştır. Bu amaçla 2012 yılı temmuz ve ağustos aylarında, 2013 yılı şubat ve nisan aylarında arazi ... -
Öncesinde Acinos olarak bilinen Türkiye'deki altı Clinopodium taksonunun nutlet morfolojisi
(2014)Lamiaceae'nin Satureja, Calamintha, Micromeria, Clinopodium ve Acinos cinslerine ait türlerin bir grubu genel sınırları içinde karışıklığa neden olmaktadır. Bu çalışmada, öncesinde Acinos olarak bilinen Türkiye Florası'ndaki ... -
Taxonomical and morphological studies on the genus Calamintha Miller (Lamiaceae) in Turkey
(2009)Türkiye Florası’nda Calamintha Miller (Lamiaceae) cinsi 6’sı endemik olmak üzere 9 tür ve 13 takson ile temsil edilmektedir. Bu çalışmada Calamintha cinsine ait 13 takson sistematik ve morfolojik yönden incelenmiş, ... -
Nutlet surface micromorphology of the genus nepeta L.(lamiaceae) in Turkey
(2008)Nepeta L. cinsinin nutlet karakterleri taksonomik öneme sahiptir. Bu çalışmada, Türkiye'de yayılışı olan Nepeta türlerinin nutlet morfolojisi stereoskopik ve taramalı electron mikroskobu kullanılarak (SEM) incelenmiştir. ... -
Seed morphology of some Genista taxa growing in Turkey
(2013)Birçok Angiosperm familyasında tohum makro ve mikromorfolojisi taksonomik öneme sahiptir. Bu çalışmada, Türkiye’de yetişen bazı Genista tohumlarının stero ve taramalı elekton mikroskobu (SEM) kullanılarak morfolojileri ... -
Türkiye Aristolochia L. türlerinin yaprak morfolojisi ve anatomileri üzerinde çalışmalar
(1998)Türkiye Aristolochia türlerinin yaprak morfoloji ve anatomileri incelenmiştir. Anatomik çalışmalar yaprak laminası üzerinde yapılmıştır. Yaprak laminasının orta kısmından enine, üst ve alt yüzünden alınan yüzeysel kesitler ... -
Development of Solid Lipid Gene Delivery System
(2016)Rekombinant DNA teknolojisindeki ilerlemelerin doğal sonucu olarak, kalıtsal hastalıkların iyileştirilmesi için gen tedavisi gündeme gelmiştir. Gen tedavisinde amaç, vücuttan alınan hücreler içinde yeni genetik materyalin ... -
Morpho-anatomical investigations on Ajuga postii Briq and Ajuga relicta P.H.Davis
(2017)Yapılan çalışma ile Türkiye'de lokal endemik türler olan Ajuga postii ve Ajuga relicta (Lamiaceae)'nın morfolojik ve anatomik özellikleri belirlenmiştir. Buna göre A. postii'nin korollası koyu pembe-mor (kuruyunca morumsu) ...
