Güncel Gönderiler: Eczacılık Fakültesi
Toplam kayıt 1731, listelenen: 441-460
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Synthesis and antinociceptive activities of some pyrazoline derivatives
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2009)In the present study, some pyrazoline derivatives were synthesized to investigate their potential antinociceptive activities. 1-[(Benzoxazole/benzimidazole-2-yl)thioacetyl]pyrazoline derivatives were obtained by reacting ... -
New triazole and triazolothiadiazine derivatives as possible antimicrobial agents
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2008)Triazole and triazoles fused with six-membered ring systems are found to possess diverse applications in the fields of medicine, agriculture and industry. The new 1,2,4-triazole and 1,2,4-triazolo[3,4-b][1,3,4]thiadiazine ... -
Synthesis and anticandidal activity of some imidazopyridine derivatives
(Taylor & Francis LTD, 2008)New hydrazide derivatives of imidazo[1,2-a]pyridine have been synthesized and evaluated for anticandidal activity. The reaction of imidazo[1,2-a]pyridine-2-carboxylic acid hydrazides with various benzaldehydes gave ... -
Synthesis and Evaluation of New Thiazolyl Hydrazone Derivatives as Potential Anticancer Agents
(Bentham Science Publ LTD, 2017)Background: In recent years, thiazole derivatives incorporated with hydrazone moiety have attracted a great deal of interest due to their pivotal role in the field of current cancer research. Methods: In the present study, ... -
Synthesis and Anticandidal Activity Evaluation of New Benzimidazole-Thiazole Derivatives
(MDPI, 2017)Azole-based antifungal agents constitute one of the important classes of antifungal drugs. Hence, in the present work, 12 new benzimidazole-thiazole derivatives 3a-3l were synthesized to evaluate their anticandidal activity ... -
Synthesis, antimicrobial activity and cytotoxicity of novel oxadiazole derivatives
(Taylor & Francis LTD, 2012)In the present study, 5-substituted-1,3,4-oxadiazolin-2-thiones (1a-b) were synthesized via the ring closure reactions of appropriate acid hydrazides with carbon disulphide. N-(Benzothiazol-2-yl)-2-[[5-substituted-1,3,4- ... -
Antifungal, mosquito deterrent, and larvicidal activity of N-(benzylidene)-3-cyclohexylpropionic acid hydrazide derivatives
(Springer Birkhauser, 2013)Hydrazone derivatives possess good antifungal and insecticidal activities and their structures are used in pesticide design. In the present study, for the first time, ten hydrazone derivatives (1-10) were evaluated for ... -
New pyrazoline derivatives and their antidepressant activity
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2010)Some triazolo-pyrazoline derivatives were synthesized to investigate their potential antidepressant activities. The chemical structures of the compounds were elucidated by IR, NMR and FAB(+)-MS spectral data and elemental ... -
Synthesis and analgesic activity of some acetamide derivatives
(Informa Healthcare, 2012)In the present study, some acetamide derivatives were synthesized and their potential analgesic activities were investigated. N-(benzothiazol-2-yl)-2-[(1-substituted-1H-tetrazol-5-yl) thio] acetamide derivatives were ... -
Synthesis and Antituberculosis Activity of New Hydrazide Derivatives
(Wiley-V C H Verlag GMBH, 2008)The increasing clinical importance of drug-resistant mycobacterial pathogens, especially Mycobacterium tuberculosis, has lent additional urgency to microbiological research and new antimycobacterial compound development. ... -
Synthesis and In Vitro Evaluation of Some Hydrazone Derivatives as Potential Antibacterial Agents
(Bentham Science Publ LTD, 2014)Nineteen N'-(benzylidene)-2-[(pyrimidin-2-yl)thio]acetohydrazides were obtained via the nucleophilic addition-elimination reaction of 2-[(pyrimidin-2-yl)thio)]acetohydrazide with aromatic aldehydes. The synthesized compounds ... -
Synthesis and In Vitro Evaluation of New Thiosemicarbazone Derivatives as Potential Antimicrobial Agents
(Hindawi LTD, 2016)In an effort to develop potent antimicrobial agents, new thiosemicarbazone derivatives were synthesized via the reaction of 4-[4-(trifluoromethyl)phenyl]thiosemicarbazide with aromatic aldehydes. The compounds were evaluated ... -
Synthesis and Evaluation of A New Series of Thiazole Derivatives as Potential Antitumor Agents and MMP Inhibitors
(Bentham Science Publ LTD, 2017)Background: In recent years, the relationship between overexpression of matrix metalloproteinases ( MMPs) and tumor invasion/metastasis has prompted researchers to develop MMP inhibitors as anticancer drugs. Objective: The ... -
Synthesis and Biological Evaluation of Some Hydrazone Derivatives as Anti-inflammatory Agents
(Bentham Science Publ LTD, 2012)In the present study, some hydrazone derivatives were synthesized via the reaction of 3-cyclohexylpropionic acid hydrazide with various benzaldehydes. The chemical structures of the compounds were elucidated by spectroscopic ... -
Synthesis and Evaluation of Anti-acetylcholinesterase Activity of Some Benzothiazole Based New Piperazine-dithiocarbamate Derivatives
(Georg Thieme Verlag Kg, 2015)In this present study some benzothiazole derivatives bearing piperazine and thiocarbamate moieties were synthesized and their potential anticholinesterase properties were investigated. A set of 30 new compounds of ... -
Toxicity and Synergistic Activities of Chalcones Against Aedes aegypti (Diptera: Culicidae) and Drosophila melanogaster (Diptera: Drosophilidae)
(Oxford University Press Inc, 2017)Mosquito-borne illnesses are of great concern throughout the world, and chemical insecticides are commonly employed to decrease mosquito populations. However, the developmental insecticide pipeline for vector control has ... -
Synthesis of Some Thienyl-Triazine Derivatives and Antimicrobial Activity
(Asian Journal Of Chemistry, 2010)Some 4-(1-aryl-ethylideneamino)-5-phenyl-1,4-dihydro-2H-[2,4]triazine-3-thione derivatives were synthesized and evaluated for their antimicrobial activity. The reaction of 2-acetylfuran or 2-acetyl-thiophene with ... -
Synthesis of Some Thiadiazole Derivatives as New Anticonvulsant Agents
(Elsevier Science BV, 2011)… -
Synthesis and Biological Evaluation of New Cholinesterase Inhibitors for Alzheimer's Disease
(MDPI, 2018)Alzheimer's disease (AD) is a neurodegenerative disorder mostly influencing the elderly, and causes death due to dementia. The main pathogenic feature connected with the progression of this multifactorial disease is the ...