Güncel Gönderiler: Eczacılık Fakültesi
Toplam kayıt 1731, listelenen: 121-140
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Formulation and in vitro-in vivo evaluation of piribedil solid lipid micro- and nanoparticles
(Taylor & Francis LTD, 2001)Modification of the dissolution rate and, thus, the enhancement of the bioavailability of a dopaminergic drug, piribedil, which has a low aqueous solubility and short elimination half-life have been the aim in this study. ... -
Preparation of prolonged release clarithromycin microparticles for oral use and their in vitro evaluation
(Pharmaceutical Soc Korea, 2006)Prolonged release microparticles of clarithromycin (CL) were prepared using Eudragit RL 100 and RS 100 by spray-drying and casting-drying techniques. For the characterization of those microparticles, preparation yield, ... -
Preparation and in vitro evaluation of pyridostigmine bromide microparticles
(Elsevier Science BV, 2002)Pyridostigmine bromide (PB) is an anticholinesterase agent whose aqueous solubility is high and which has a short elimination half-life. Its dosage rate in the treatment of myastenia gravis is frequent due to the short ... -
Enhancement in dissolution pattern of piribedil by molecular encapsulation with beta-cyclodextrin
(Prous Science, Sa, 2006)The aim of this was to improve the dissolution behavior of piribedil by molecular encapsulation with beta-cyclodextrin (beta-CD). Toward this aim, physical mixing, co-grinding, and spray-drying methods were used to prepare ... -
Studies on vaginal bioadhesive tablets of acyclovir
(Govi-Verlag GMBH, 2000)Bioadhesive vaginal tablets were prepared using poly(acrylic acid) (PAA); Methylcellulose (MC), carboxymethyl cellulose (CMC), hydroxypropyl cellulose (HPC) and hydroxypropylmethyl cellulose (HPMC) as bioadhesive polymers ... -
In vitro evaluation of sustained released matrix tablet formulations of clarithromycin
(Osterreichische Apotheker-Verlagsgesellschaft m.b.H., 2005)Sustained release matrix tablets of clarithromycin were prepared using different polymers as Hydroxypropyl methylcellulose (HPMC), Carbopol 934 and Eudragit RL/PO by direct compression technique. For the quality control ... -
Studies on prolonged release matrix tablet formulations of hydralazine hydrochloride
(2003)The purpose of this study was to prepare prolonged release tablet formulations of hydralazine hydrochloride which has been used as an antihypertensive agent. To achieve this, carbomers (Carbopol® 834, 934, 940 and 1342) ... -
Formulation and In Vitro Evaluation of Moxifloxacin Hydrochloride-Loaded Polymeric Nanoparticles for Ocular Application
(Colegio Farmaceuticos Provincia De Buenos Aires, 2018)The primary purpose of this study was to extend the time of interaction of the carrier with the negatively charged ocular surface for enhanced penetration in order to improve ocular bioavailability. Moxifloxacin hydrochloride ... -
Design and Characterization of Montelukast Sodium Loaded Kollidon (R) SR Nanoparticles and Evaluation of Release Kinetics and Cytotoxicity Potential
(Colegio Farmaceuticos Provincia De Buenos Aires, 2019)The objective of this research was to design and characterize montelukast sodium (MS) loaded novel nanosized and biocompatible Kollidon (R) SR nanoparticles to provide prolonged release behavior that can improve bioavailability, ... -
Microencapsulation of ketorolac tromethamine by means of a coacervation phase separation technique induced by the addition of non-solvent
(Taylor & Francis LTD, 1998)Ketorolac tromethamine (KT) is a non-steroidal drug with potent analgesic and anti-inflammatory activity and is absorbed rapidly (T-max (1.0h) with an efficiency >87% following oral and intramuscular administration. The ... -
A Polarographic Study on Dipyridamole and Its Determination in Commercial Tablets
(Marcel Dekker Inc, 1991)The direct current polarographic behaviour of dipyridamole, a coronary vasodilator, in the supporting electrolyte consisting of 0.2 M KCl, 20% (v/v) ethanol and buffer solutions is described in this study. Morphologically ... -
Bioavailability of Verapamil Hydrochloride From Nasal Delivery Systems
(Editions De Sante, 1994)… -
Olopatadine hydrochloride loaded Kollidon (R) SR nanoparticles for ocular delivery: Nanosuspension formulation and in vitro-in vivo evaluation
(Elsevier Science BV, 2019)Introduction: Allergic eye diseases includes a spectrum of diseases, with each state being characterized by a complicated immunopathology. In the present study, polymeric Kollidon (R) SR nanoparticles loaded with olopatadine ... -
Desloratadine-Eudragit (R) RS100 Nanoparticles: Formulation and Characterization
(Turkish Pharmacists Assoc, 2017)Objectives: The objective of the present study was to formulate Desloratadine-Eudragit (R) RS100 nanoparticles and investigate the characteristics of the prepared nanoparticles. Materials and Methods: The nanoparticles ... -
Vitamin E Loaded Fabrics as Cosmetotextile Products: Formulation and Characterization
(Ege University, 2018)Skin fights constantly during the day to be saved from free radicals caused by UV rays and pollution. However, skin cells repair damage and restore complexion during sleep. Enhancement of repair and restoration can be ... -
Inclusion complexes of fluconazole with beta-cyclodextrin: physicochemical characterization and in vitro evaluation of its formulation
(Springer, 2011)Fluconazole (FZ) is a triazole antifungal drug administered orally or intravenously. It is employed for the treatment of mycotic infections. However, the efficacy of FZ is limited with its poor aqueous solubility and low ... -
Dexketoprofen Trometamol-Loaded Kollidon (R) SR and Eudragit (R) RS 100 Polymeric Nanoparticles: Formulation and In Vitro-In Vivo Evaluation
(Colegio Farmaceuticos Provincia De Buenos Aires, 2017)Development and in vivo/in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized, controlled release drug delivery system was aimed in this study.. DT-loaded Kollidon (R) SR (KSR) and Eudragit (R) RS 100 (ERS) ... -
Development of nano-sized ketoprofen lysine incorporated Eudragit (R) S100 nanomedicine by double emulsion solvent evaporation and in vitro characterization
(Journal Pharmacy & Pharmacognosy Research-Jppres, 2019)Context: Pain has a very important effect on the biological, psychological, sociological and economic situation of a patient. Nanoparticles (NPs) are being extensively investigated as drug delivery systems worldwide for ... -
Supervised Machine Learning Algorithms for Evaluation of Solid Lipid Nanoparticles and Particle Size
(Bentham Science Publ LTD, 2018)Aims and Objectives: Solid Lipid Nanoparticles (SLNs) are pharmaceutical delivery systems that have advantages such as controlled drug release, long-term stability etc. Particle Size (PS) is one of the important criteria ... -
New Approach to Hypertension Treatment: Carvediol-Loaded PLGA Nanoparticles, Preparation, In Vitro Characterization and Gastrointestinal Stability
(Colegio Farmaceuticos Provincia De Buenos Aires, 2018)Carvedilol (CVL) has advantages over the first generation of beta-blockers in patients with heart failure due to its properties of reducing cardiovascular morbidity and mortality. On the other hand, CVL has a short half-life ...