Yayıncı "Wiley" Eczacılık Fakültesi için listeleme
Toplam kayıt 31, listelenen: 1-20
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Antiepileptic drugs: Impacts on human serum paraoxonase-1
(Wiley, 2017)Serum paraoxonase (PON1) is a key enzyme related to high-density lipoprotein (HDL)-cholesterol particle. It can prevent the oxidation of low-density lipoprotein (LDL) and HDL. The present article focuses on the in vitro ... -
Antioxidant Activity and Phenolic Acid Constituents of Chestnut (Castania Sativa Mill.) Honey and Propolis
(Wiley, 2009)This study describes the constituents of phenolic acids and antioxidant activities of chestnut (Castania sativa Mill.) honeys and propolis in Turkey. Antioxidant activity of the chestnut honeys and propolis were examined ... -
Antiproliferative, Cytotoxic, and Apoptotic Effects of New Benzimidazole Derivatives Bearing Hydrazone Moiety
(Wiley, 2018)In order to take the advantages of the anticancer properties of benzimidazoles and hydrazones, we synthesized new 4-(5-chloro-1H-benzimidazol-2-yl)-benzoic acid benzylidene hydrazide derivatives (3a-3t) and evaluated their ... -
Assessment of the inhibitory effects and molecular docking of some sulfonamides on human serum paraoxonase 1
(Wiley, 2017)Paraoxonase-1 (PON1) is an organophosphate hydrolyzer and antiatherogenic enzyme. Due to the PON1's crucial functions, inhibitors and activators of PON1 must be known for pharmacological applications. In this study, we ... -
Central Nervous System Activities of Hypericum origanifolium Extract via GABAergic and Opioidergic Mechanisms
(Wiley, 2013)Pharmacological effects of hydroalcoholic extract prepared from Hypericum origanifolium Willd. (Guttiferae) on behavioral parameters and pain perceptions of mice were investigated in this study. Depression, anxiety, ... -
Chemical composition and phagocyte immunomodulatory activity of Ferula iliensis essential oils
(Wiley, 2017)Essential oil extracts from Ferula iliensis have been used traditionally in Kazakhstan for treatment of inflammation and other illnesses. Because little is known about the biologic activity of these essential oils that ... -
Citalopram Induces Reproductive Toxicity in Male Rats
(Wiley, 2017)Background: Citalopram hydrobromide (CTL) has been shown to cause sexual dysfunction; however, its reproductive toxicity potential has not been sufficiently elucidated in men. Therefore, we aimed to clarify the toxic effects ... -
Composition and anticandidal activity of the essential oil of Chaerophyllum byzantinum Boiss.
(Wiley, 2006)Water-distilled essential oil of Chaerophyllum byzantinum Boiss., collected from Bursa, Uludag, in Turkey, was analyzed by GC and GC/MS. Sixty-five components were identified representing 94.6% of the oil. Sabinene (30.0%), ... -
Discovery of potent carbonic anhydrase, acetylcholinesterase, and butyrylcholinesterase enzymes inhibitors: The new amides and thiazolidine-4-ones synthesized on an acetophenone base
(Wiley, 2017)Compounds containing nitrogen and sulfur atoms can be widely used in various fields, including industry, medicine, biotechnology, and chemical technology. Among them, amides of acids and heterocyclic compounds have an ... -
Effect of Horse-chestnut seed extract on matrix metalloproteinase-1 and-9 during diabetic wound healing
(Wiley, 2019)The effects of aqueous-ethanol extract of Horse chestnut (HCE) on MMP-1 and MMP-9 expressions during cutaneous wound healing in diabetic rats were investigated in this study. The expressions of MMP-1 and MMP-9, wound ... -
Effect of subacute agomelatine treatment on painful diabetic neuropathy: involvement of catecholaminergic mechanisms
(Wiley, 2016)In this study, we investigated the effects of subacute agomelatine (40 and 80 mg/kg) administration on chronic hyperglycemia, metabolic parameters, and pain perception in streptozotocin-induced diabetic rats. Fasting blood ... -
Effects of Hypericum montbretti Extract on the Central Nervous System and Involvement of GABA (A)/Benzodiazepine Receptors in its Pharmacological Activity
(Wiley, 2012)The present study was undertaken to investigate the putative activity of a methanol extract of Hypericum montbretti (Guttiferae) on the central nervous system. Rutin (1519 ppm) and quercitrin (784 ppm) were identified as ... -
Essential oil composition of Seseli petraeum M. Bieb. and Seseli andronakii Woron. growing in Turkey
(Wiley, 2006)Essential oils obtained by hydrodistillation from fruits of Seseli petraeum M. Bieb. and Seseli andronakii Woron. were analysed by GC and GC-MS. In total, 32 compounds were identified representing 95.7% of the total oil ... -
Evaluation of chalcones as inhibitors of glutathione S-transferase
(Wiley, 2018)Glutathione S-transferases (GSTs) are the superfamily of multifunctional detoxification isoenzymes and play an important role in cellular signaling. In the present study, potential inhibition effects of chalcones were ... -
Frequency of angiotensin II type 1 receptor gene polymorphism in Turkish acute stroke patients
(Wiley, 2013)This study was performed in acute stroke patients in the Turkish population to determine the frequency of the A1166C polymorphism in the AT1 gene and to examine the role of this polymorphism in acute stroke development. ... -
Headspace-SPME and hydrodistillation of two fragrant Artemisia sp.
(Wiley, 2005)The family Asteraceae comprises aromatic plants with a strong distinctive fragrance. Artemisia species belonging to this family are known to contain essential oils. Fresh aerial parts of Artemisia spicigera C. Koch and A. ... -
Hepatoprotective Activity of Hypericum-Perforatum L Alcoholic Extract in Rodents
(Wiley, 1992)In recent years, interest in the hepatoprotective plants and plant based chemicals is increasing. In Turkish folk medicine, Hypericum perforatum L. has been used for various purposes including liver protection. The ... -
Identification of volatile aroma compounds of strawberry wine using solid-phase microextraction techniques coupled with gas chromatography-mass spectrometry
(Wiley, 2006)Aroma compounds of strawberry wine were trapped by both headspace (HS) and immersion (IM) solid-phase microextraction (SPME). In the strawberry wine, esters were found to be the major compounds detected by both techniques. ... -
Inhibition effects of pesticides on glutathione-S-transferase enzyme activity of Van Lake fish liver
(Wiley, 2018)Glutathione-S-transferases (GSTs) have a function in xenobiotic metabolism. They are a significant multifunctional family with a wide variety of catalytic activities. In the current study, we determined in vitro inhibition ...