dc.contributor.author | Nganou, Blaise Kemajou | |
dc.contributor.author | Konga, Ingrid Simo | |
dc.contributor.author | Fankam, Aime G. | |
dc.contributor.author | Bitchagno, Gabin Thierry M. | |
dc.contributor.author | Sonfack, Gaielle | |
dc.contributor.author | Nayim, Paul | |
dc.contributor.author | Tane, Pierre | |
dc.date.accessioned | 2019-10-20T09:03:10Z | |
dc.date.available | 2019-10-20T09:03:10Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 1478-6419 | |
dc.identifier.issn | 1478-6427 | |
dc.identifier.uri | https://dx.doi.org/10.1080/14786419.2018.1465424 | |
dc.identifier.uri | https://hdl.handle.net/11421/16646 | |
dc.description | WOS: 000475501100008 | en_US |
dc.description | PubMed ID: 29683342 | en_US |
dc.description.abstract | Allanblackia genus, an endless source of bioactive compounds, was investigated for its antibacterial properties. The chemical study of the methanol extract from the fruits of Allanblackia gabonensis resulted in the isolation of the undescribed guttiferone BL (1) along with the known kaempferol (2), morelloflavone (3), morelloflavone 7 ''-O-beta-D-glucopyranoside (4), beta-sitosterol 3-O-beta-D-glucopyranoside and beta-sitosterol. Their structures were determined using spectrometry and spectroscopic techniques. The antibacterial activity was evaluated against five Gram-negative and two Gram-positive strains using a broth micro-dilution method. Compounds displayed low to significant activity against the tested bacterial strains with MICs ranging from 8 to 512 mu g/mL. Morelloflavone (3) presented significant activity against E. coli ATCC8739 (MIC = 8 mu g/mL) while guttiferone BL (1) exhibited low activity (MICs = 256-512 mu g/mL) against all the tested strains. The crude extract also had moderate to significant activity against the tested bacterial strains. [GRAPHICS] . | en_US |
dc.description.sponsorship | Scientific Research Projects Commission of Anadolu University, Eskisehir, Turkey [1306F110] | en_US |
dc.description.sponsorship | IC would like to thank the Scientific Research Projects Commission of Anadolu University, Eskisehir, Turkey for the funding grant (1306F110). Authors are thankful to the Cameroon National Herbarium for the plant identification. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Taylor & Francis LTD | en_US |
dc.relation.isversionof | 10.1080/14786419.2018.1465424 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Allanblackia Gabonensis | en_US |
dc.subject | Antibacterial Activity | en_US |
dc.subject | Clusiaceae | en_US |
dc.subject | Guttiferone Bl | en_US |
dc.title | Guttiferone BL with antibacterial activity from the fruits of Allanblackia gabonensis | en_US |
dc.type | article | en_US |
dc.relation.journal | Natural Product Research | en_US |
dc.contributor.department | Anadolu Üniversitesi, Fen Fakültesi, Fizik Bölümü | en_US |
dc.identifier.volume | 33 | en_US |
dc.identifier.issue | 18 | en_US |
dc.identifier.startpage | 2638 | en_US |
dc.identifier.endpage | 2646 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |