| dc.contributor.author | Rosselli, Sergio | |
| dc.contributor.author | Bruno, Maurizio | |
| dc.contributor.author | Raimondo, Francesco Maria | |
| dc.contributor.author | Spadaro, Vivienne | |
| dc.contributor.author | Varol, Mehmet | |
| dc.contributor.author | Koparal, Ayşe Tansu | |
| dc.contributor.author | Maggio, Antonella | |
| dc.date.accessioned | 2019-10-20T08:00:46Z | |
| dc.date.available | 2019-10-20T08:00:46Z | |
| dc.date.issued | 2012 | |
| dc.identifier.issn | 1420-3049 | |
| dc.identifier.uri | https://dx.doi.org/10.3390/molecules17078186 | |
| dc.identifier.uri | https://hdl.handle.net/11421/16173 | |
| dc.description | WOS: 000306752700042 | en_US |
| dc.description | PubMed ID: 22777187 | en_US |
| dc.description.abstract | A phytochemical analysis of the dichloromethane extract from the flowers of a subspecies of Tanacetum vulgare growing in Sicily was carried out. Five known sesquiterpene lactones with the eudesmane skeleton have been isolated and the cytotoxic activity of these compounds was tested in vitro on A549 (human lung carcinoma epithelial-like) and V79379A (Chinese hamster lung fibroblast-like) cells using the tetrazolium salt reduction (MTT) assay. All of tested compounds induced high time- and concentration-dependent cytotoxic effects. | en_US |
| dc.description.sponsorship | Italian Government fund MIUR | en_US |
| dc.description.sponsorship | This research was supported by Italian Government fund MIUR PRIN 2009 "Composti naturali da piante mediterranee e loro derivati sintetici con attivita' antitumorale". | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | MDPI | en_US |
| dc.relation.isversionof | 10.3390/molecules17078186 | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Tanacetum Vulgare | en_US |
| dc.subject | Sesquiterpenes | en_US |
| dc.subject | Eudesmanolides | en_US |
| dc.subject | Cytotoxic Activity | en_US |
| dc.title | Cytotoxic Effect of Eudesmanolides Isolated from Flowers of Tanacetum vulgare ssp siculum | en_US |
| dc.type | article | en_US |
| dc.relation.journal | Molecules | en_US |
| dc.contributor.department | Anadolu Üniversitesi, Fen Fakültesi, Biyoloji Bölümü | en_US |
| dc.identifier.volume | 17 | en_US |
| dc.identifier.issue | 7 | en_US |
| dc.identifier.startpage | 8186 | en_US |
| dc.identifier.endpage | 8195 | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.contributor.institutionauthor | Koparal, Ayşe Tansu | |
