| dc.contributor.author | Yurttaş, Leyla | |
| dc.contributor.author | Ertaş, Merve | |
| dc.contributor.author | Cankılıç, Meral Yılmaz | |
| dc.contributor.author | Demirayak, Şeref | |
| dc.date.accessioned | 2019-10-19T16:02:34Z | |
| dc.date.available | 2019-10-19T16:02:34Z | |
| dc.date.issued | 2017 | |
| dc.identifier.issn | 1307-2080 | |
| dc.identifier.uri | https://dx.doi.org/10.23893/1307-2080.APS.0554 | |
| dc.identifier.uri | https://hdl.handle.net/11421/13804 | |
| dc.description.abstract | A series of 3-[(4-aryl-2-thiazolyl)hydrazone]-1H-indol-2,3-dione derivatives (2a-f) were designed and synthesized using isatin as starting material. The obtained thiazole compounds were screened to investigate their antituberculosis activity against Mycobacterum tuberculosis H37RV (ATCC 27294). Among them, two compounds 2c and 2d were displayed antitubercular potential two-fold greater than standard drugs | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | University of Istanbul | en_US |
| dc.relation.isversionof | 10.23893/1307-2080.APS.0554 | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Antimycobacterial Activity | en_US |
| dc.subject | Indole | en_US |
| dc.subject | Isatin | en_US |
| dc.subject | Thiazole | en_US |
| dc.title | Synthesis and antimycobacterial activity evaluation of isatin-derived 3- [(4-aryl-2-thiazolyl])hydrazone]-1H-indol-2,3-diones | en_US |
| dc.type | article | en_US |
| dc.relation.journal | Acta Pharmaceutica Sciencia | en_US |
| dc.contributor.department | Anadolu Üniversitesi, Eczacılık Fakültesi, Farmasötik Kimya Anabilim Dalı | en_US |
| dc.identifier.volume | 55 | en_US |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.startpage | 51 | en_US |
| dc.identifier.endpage | 58 | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US] |
| dc.contributor.institutionauthor | Yurttaş, Leyla | |
| dc.contributor.institutionauthor | Demirayak, Şeref | |
