dc.contributor.author | Yurttaş, Leyla | |
dc.contributor.author | Duran, Murat | |
dc.contributor.author | Demirayak, Şeref | |
dc.contributor.author | Karaca Gencer, Hülya | |
dc.contributor.author | Tunalı, Yağmur | |
dc.date.accessioned | 2019-10-19T14:45:01Z | |
dc.date.available | 2019-10-19T14:45:01Z | |
dc.date.issued | 2013 | |
dc.identifier.issn | 0960-894X | |
dc.identifier.issn | 1464-3405 | |
dc.identifier.uri | https://dx.doi.org/10.1016/j.bmcl.2013.10.024 | |
dc.identifier.uri | https://hdl.handle.net/11421/13666 | |
dc.description | WOS: 000327787700045 | en_US |
dc.description | PubMed ID: 24176398 | en_US |
dc.description.abstract | In this work, some new 2-[(4,5-dimethyl-1-(arylamino)-1H-imidazol-2-yl)thio]-1-(aryl) ethanone derivatives were synthesized and investigated for their antibacterial, antifungal and anticancer activities. Toxicity of the most effective compounds was established by performing Brine-Shrimp lethality assay. Antifungal activity of the compounds was found to be higher than antibacterial and anticancer activities of the compounds | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Pergamon-Elsevier Science LTD | en_US |
dc.relation.isversionof | 10.1016/j.bmcl.2013.10.024 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Imidazole | en_US |
dc.subject | Antimicrobial | en_US |
dc.subject | Brine-Shrimp Test | en_US |
dc.subject | Anticancer | en_US |
dc.title | Synthesis and initial biological evaluation of substituted 1-phenylamino-2-thio-4,5-dimethyl-1H-imidazole derivatives | en_US |
dc.type | article | en_US |
dc.relation.journal | Bioorganic & Medicinal Chemistry Letters | en_US |
dc.contributor.department | Anadolu Üniversitesi, Eczacılık Fakültesi, Farmasötik Kimya Anabilim Dalı | en_US |
dc.identifier.volume | 23 | en_US |
dc.identifier.issue | 24 | en_US |
dc.identifier.startpage | 6764 | en_US |
dc.identifier.endpage | 6768 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.contributor.institutionauthor | Yurttaş, Leyla | |
dc.contributor.institutionauthor | Demirayak, Şeref | |
dc.contributor.institutionauthor | Karaca Gencer, Hülya | |
dc.contributor.institutionauthor | Tunalı, Yağmur | |