| dc.contributor.author | Maillard, Ludovic T. | |
| dc.contributor.author | Bertout, Sebastien | |
| dc.contributor.author | QuinÖnero, Ophelie | |
| dc.contributor.author | Akalın Çiftçi, Gülsen | |
| dc.contributor.author | Turan, Gülhanulan | |
| dc.contributor.author | Fulcrand, Pierre | |
| dc.contributor.author | Masurier, Nicolas | |
| dc.date.accessioned | 2019-10-19T14:44:48Z | |
| dc.date.available | 2019-10-19T14:44:48Z | |
| dc.date.issued | 2013 | |
| dc.identifier.issn | 0960-894X | |
| dc.identifier.issn | 1464-3405 | |
| dc.identifier.uri | https://dx.doi.org/10.1016/j.bmcl.2013.01.039 | |
| dc.identifier.uri | https://hdl.handle.net/11421/13617 | |
| dc.description | WOS: 000315331500049 | en_US |
| dc.description | PubMed ID: 23403080 | en_US |
| dc.description.abstract | Eighteen new hydrazino-1,3-thiazole derivatives were evaluated against 8 strains of multi-resistant Candida spp. Introduction of an indolyl moiety linked to the hydrazone function enhanced the in vitro anti-Candida activity, with an activity spectrum towards Candida albicans strains. Introduction of a (S)-2-aminoethyl chain on the thiazole nucleus largely enhanced the in vitro antifungal activity, with a selectivity oriented towards non-C. albicans species | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | Pergamon-Elsevier Science LTD | en_US |
| dc.relation.isversionof | 10.1016/j.bmcl.2013.01.039 | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Thiazole | en_US |
| dc.subject | Hydrazone | en_US |
| dc.subject | Candida Spp. | en_US |
| dc.subject | Antifungal Activity | en_US |
| dc.title | Synthesis and anti-Candida activity of novel 2-hydrazino-1,3-thiazole derivatives | en_US |
| dc.type | article | en_US |
| dc.relation.journal | Bioorganic & Medicinal Chemistry Letters | en_US |
| dc.contributor.department | Anadolu Üniversitesi, Eczacılık Fakültesi, Farmasötik Kimya Anabilim Dalı | en_US |
| dc.identifier.volume | 23 | en_US |
| dc.identifier.issue | 6 | en_US |
| dc.identifier.startpage | 1803 | en_US |
| dc.identifier.endpage | 1807 | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.contributor.institutionauthor | Akalın Çiftçi, Gülsen | |
