Yazar "Rollas, Sevim" için Makale Koleksiyonu listeleme
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Studies on hydrazide-hydrazones derivatives as acetylcholinesterase inhibitors
Abu Mohsen, Usama; Koçyiğit-Kaymakçıoğlu, Bedia; Oruç-Emre, Emine Elçin; Kaplancıklı, Zafer Asım; Rollas, Sevim (Aves Press LTD, 2015)Objective: Fifteen hidrazide-hydrazone derivatives were synthesized and evaluated for their ability to inhibit acetylcholinesterase (AChE) using a modification of Ellman's spectrophotometric method. Methods: Anti-acetylc ... -
The synthesis and evaluation of anti-acetylcholinesterase activity of some 4(3H)-quinazolinone derivatives bearing substituted 1,3,4- thiadiazole
Uraz, Mine; Karakus, Sevgi; Abu Mohsen, Usama; Kaplancıklı, Zafer Asım; Rollas, Sevim (Marmara University, Fac Medicine, 2017)In the present study, a series of 4(3H)-quinazolinone derivatives (5a-f) were synthesized through the cylization reaction of substituted 1,3,4-thiadiazoles containing an aromatic primary amin and anthranilic acid in the ...