Başlık için Farmasötik Kimya Anabilim Dalı listeleme
Toplam kayıt 345, listelenen: 51-70
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Electrochemical Investigation of Interactions between Potential DNA Targeted Compounds, 2,4-Di- and 2,3,4-Trisubstituted Benzimidazo[1,2-a]pyrimidines and Nucleic Acid
(Japan Soc Analytical Chemistry, 2010)The electrochemical aspects of interactions between DNA and two organic compounds are discussed herein. Potential DNA targeted compounds, 2-methyl-4-phenyl-benzo[4,5]imidazo[1,2-a]pyrimidine (C1) and 2,3,4-trimethyl-benz ... -
Erratum: Synthesis and Evaluation of Anti-acetylcholinesterase Activity of Some Benzothiazole Based New Piperazine-dithiocarbamate Derivatives (Drug Research (2015) DOI: 10.1055/s-0034-1375613)
(Georg Thieme Verlag, 2015)[No abstract available] -
Eskişehir'de Vitamin Kullanım Alışkanlıkları Üzerine Dar Kapsamlı Bir Araştırma
(2013)Bu çalışmada, Eskişehir'de dört farklı sosyo-kültürel grubu temsil eden 500 kişinin vitamin kullanım alışkanlıkları ve bu alışkanlıkları etkileyen faktörler çalışılmıştır. Araştırmaya katılan denekler tesadüfi örnekleme ... -
Ethnobotany of Eskisehir and Its Environs
(Pakistan Botanical Soc, 2013)Eskisehir is located in the Central Anatolian province of Turkey. It is included in B3 grid square of Davis. There are more than 1000 plant taxa distributed in this State and its environs and nearly 220 are endemics. The ... -
Evaluation of antidepressant-like effect of 2-pyrazoline derivatives
(Birkhauser Boston Inc, 2010)Many studies have shown that pyrazoline derivatives have therapeutic potential as antidepressant drugs. In this study, we aimed to investigate the antidepressant-like effect of eight new 1-[(N,N-disubstituted thiocarbamo ... -
Exploring the toxicity and synergism of chalcone analogs as biologically-based alternatives to control insects
(American Chemical Society, 2015)… -
A facile synthesis of 2-aryl-4,5-di(2-thienyl)imidazoles under microwave irradiation and their antimicrobial activities
(2002)In this study, some 2-aryl-4,5-dithienylimidazoles were synthesized by reacting di-(2-thienyl)ethandione and a suitable aromatic aldehyde in the presence of ammonium acetate in acetic acid. Either the classical reflux ... -
A facile synthesis of some thieno/furo-[2,3-d]pyrimidine-2-yl-thioacetic acid derivatives
(HeteroCorporation, 2001)The reaction of 2-(?-chloroacetamido)-3-cyano-4,5-disubstituted thiophenes/furanes with ammonium thiocyanate in methanol or ethanol afforded methyl or ethyl (4-amino-5,6-disubstituted thieno/furo[2,3-d]-pyrimidine-2-yl)t ... -
Fighting Against Alzheimer's Disease: Synthesis of New Pyrazoline and Benzothiazole Derivatives as New Acetylcholinesterase and MAO Inhibitors
(Bentham Science Publ LTD, 2018)Background: Alzheimer's Disease (AD) is a complicated neurodegenerative disorder with a multifaceted pathogenesis. AD, characterized by gradual memory loss, falling in language ability and other cognitive deterioration, ... -
Free radical scavenging compounds in Salvia halophila Hedge and S-virgata Jacq. extracts using a postcolumn derivatization method
(Georg Thieme Verlag Kg, 2007)… -
In silico Molecular Docking and ADME Studies of 1 3,4-Thiadiazole Derivatives in Relation to in vitro PON1 Activity
(Bentham Science Publ LTD, 2019)Background: Paraoxonase 1 (PON1) is a paraoxonase, arylesterase and lactonase associated with protection of lipoproteins and cell membranes against oxidative modification. Objective: Based on antioxidative properties of ... -
In vitro and in silico evaluation of new thiazole compounds as monoamine oxidase inhibitors
(Academic Press Inc Elsevier Science, 2019)New twenty compounds bearing thiazole ring (3a-3t) were designed and synthesized as monoamine oxidase (MAO) inhibitors. The fluorometric enzyme inhibition assay was used to determine the biological effects of synthesized ... -
In vitro antitumor activity evaluation of some 1,2,4-triazine derivatives bearing piperazine amide moiety against breast cancer cells
(Pergamon-Elsevier Science LTD, 2014)A series of 1,2,4-triazine derivatives bearing piperazine amide moiety has been synthesized and investigated for their potential anticancer activities. 1-[4-(5,6-Bis(4-subtituted phenyl)-1,2,4-triazin-3-yl) piperazin- ... -
Indomethacin based new triazolothiadiazine derivatives: Synthesis, evaluation of their anticancer effects on T98 human glioma cell line related to COX-2 inhibition and docking studies
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2016)In the current work, new 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine derivatives (1-8) were synthesized via the ring closure reaction of 2-bromoacetophenone derivatives with 4-amino-5-[(5-methoxy-2-methyl-1(4-chlorobenzoyl)- ... -
Investigation of the inhibitory effects of isoindoline-1,3-dion derivatives on hCA-I and hCA-II enzyme activities
(Elsevier B.V., 2019)Inhibition of carbonic anhydrase (CA) has emerged as a promising approach for the treatment of a variety of diseases such as glaucoma, epilepsy, obesity and cancer. As a result, the design of CA inhibitors (CAIs) is an ... -
Microwave supported synthesis of some novel 1,3-Diarylpyrazino[1,2-a] benzimidazole derivatives and investigation of their anticancer activities
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2011)The syntheses of 1,3-diarylpyrazino[1,2-a]benzimidazole derivatives and the investigation of their anticancer activities were studied. For this, 2-aryloylbenzimidazole derivatives were reacted with 2-bromoacetophenones in ... -
A mini-survey on vitamin usage habits in eskİşehİr [Eskişehir'de vitamin kullamm ahskanhklari{dotless} üzerine dar kapsamh bir araşti{dotless}rma]
(2013)In the present study, vitamin usage habits of five hundred people representing four different socio-cultural groups in Eskişehir and the factors affecting these habits were studied. The participants of the research were ... -
Molecular modelling of 2-iminothiazoles as insecticidal activity
(Bulgarian Acad Science, 2017)Insecticides are used in agriculture, medicine, industry and by consumers, indoor. Insecticides are also claimed to be a major factor behind the increase in agricultural 20th century's productivity. On the other hand, modes ... -
N-(chroman-4-ylidene)aryloxyacetohydrazones: Synthesis and antimicrobial activity
(1997)In this study, some N-(chroman-4-ylidene)phenoxyacetohydrazone and N-(chroman-4-ylidene)phenoxypropiohydrazone compounds were synthesized. Structure of the compounds were identified by using IR, 1H NMR and MASS spectral ...