dc.contributor.author | Sen, Ali | |
dc.contributor.author | Kürkçüoğlu, Mine | |
dc.contributor.author | Bitiş, Leyla | |
dc.contributor.author | Doğan, Ahmet | |
dc.contributor.author | Başer, K. Hüsnü Can | |
dc.date.accessioned | 2019-10-19T14:15:24Z | |
dc.date.available | 2019-10-19T14:15:24Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 1041-2905 | |
dc.identifier.issn | 2163-8152 | |
dc.identifier.uri | https://dx.doi.org/10.1080/10412905.2019.1567399 | |
dc.identifier.uri | https://hdl.handle.net/11421/12816 | |
dc.description | WOS: 000463498100001 | en_US |
dc.description.abstract | The essential oil of aerial parts of Stachys subnuda Montbret & Aucher ex Benth (S. subnuda) was analyzed by gas chromatography (GC) and GC/mass spectrometry (MS). Anti-inflammatory activity was evaluated by lipoxygenase inhibition assay. The antioxidant activity was determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azinobis-3-ethylbenzothiozoline-6-sulfonic acid (ABTS) assays. Sixty-two constituents, comprising 97.1% of the total essential oil composition, were identified. Phytol (25.2%), beta-caryophyllene (11.2%), germacrene D (6.9%), and hexadecanoic acid (6.9%) were the major compounds of aerial part essential oils of S. subnuda. The essential oil showed significant radical scavenging activity with 50% inhibition (IC50) values of 0.124 and 0.204 mg/mL for ABTS and DPPH radicals, respectively. The essential oil exhibited moderate anti-inflammatory activity with an IC50 value of 0.419 mg/mL. The results indicated that S. subnuda essential oil had good anti-inflammatory and antioxidant activity. Also, this is first study on chemical composition, anti-inflammatory and antioxidant activity of S. subnuda essential oil. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Taylor & Francis Inc | en_US |
dc.relation.isversionof | 10.1080/10412905.2019.1567399 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Stachys Subnuda | en_US |
dc.subject | Essential Oil | en_US |
dc.subject | Anti-Inflammatory Activity | en_US |
dc.subject | Antioxidant Activity | en_US |
dc.title | Chemical composition of endemic Stachys subnuda Montbret & Aucher ex Benth. essential oil and its anti-inflammatory and antioxidant activities | en_US |
dc.type | article | en_US |
dc.relation.journal | Journal of Essential Oil Research | en_US |
dc.contributor.department | Anadolu Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı | en_US |
dc.identifier.volume | 31 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 326 | en_US |
dc.identifier.endpage | 334 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.contributor.institutionauthor | Kürkçüoğlu, Mine | |
dc.contributor.institutionauthor | Başer, K. Hüsnü Can | |