dc.contributor.author | Şerbetçi, Tuba | |
dc.contributor.author | Demirci, Betül | |
dc.contributor.author | Güzel, Çağla Bozkurt | |
dc.contributor.author | Kültür, Şükran | |
dc.contributor.author | Erguven, Mine | |
dc.contributor.author | Başer, K. Hüsnü Can | |
dc.date.accessioned | 2019-10-19T14:03:43Z | |
dc.date.available | 2019-10-19T14:03:43Z | |
dc.date.issued | 2010 | |
dc.identifier.issn | 1934-578X | |
dc.identifier.uri | https://hdl.handle.net/11421/12661 | |
dc.description | WOS: 000281627600009 | en_US |
dc.description | PubMed ID: 20922993 | en_US |
dc.description.abstract | The chemical compositions of the water-distilled essential oil of Stachys cretica ssp. lesbiaca Rech. fil. and S. cretica ssp. trapezuntica Rech. fil. were determined by GC and GC MS. Altogether 63 compounds were identified. The sesquiterpene hydrocarbon, germacrene D (20.3% and 12.9% respectively) was the main component identified in both oils. Furthermore, ethanol, light petroleum, dichloromethane, ethyl acetate and n-butanol extracts prepared from the aerial parts of the plants were tested for their antimicrobial activities against six bacterial strains and the yeast Candida albicans. The extracts exhibited no antibacterial activity, but the light petroleum and n-butanolic fractions showed low antifungal activities. Crude ethanolic extracts of the two subspecies were tested for their ability to inhibit the growth of HL-60 and Ishikawa human tumor cell lines. The IC(50) values were 100 mu g/mL for the HL-60 cell line and 200 mu g/mL for the Ishikawa cell line. | en_US |
dc.description.sponsorship | Scientific Research Foundation of Istanbul University [3784, UDP 7069] | en_US |
dc.description.sponsorship | This work was supported by the Scientific Research Foundation of Istanbul University Project no: 3784 and UDP 7069. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Natural Products Inc | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Stachys Cretica Ssp Lesbiaca | en_US |
dc.subject | Stachys Cretica Ssp Trapezuntica | en_US |
dc.subject | Essential Oil | en_US |
dc.subject | Antimicrobial | en_US |
dc.subject | Cytotoxicity | en_US |
dc.title | Essential Oil Composition, Antimicrobial and Cytotoxic Activities of Two Endemic Stachys cretica Subspecies (Lamiaceae) from Turkey | en_US |
dc.type | article | en_US |
dc.relation.journal | Natural Product Communications | en_US |
dc.contributor.department | Anadolu Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı | en_US |
dc.identifier.volume | 5 | en_US |
dc.identifier.issue | 9 | en_US |
dc.identifier.startpage | 1369 | en_US |
dc.identifier.endpage | 1374 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.contributor.institutionauthor | Demirci, Betül | |
dc.contributor.institutionauthor | Başer, K. Hüsnü Can | |