Kurum Yazarı "Öztürk, Yusuf" Makale Koleksiyonu İçin Listeleme
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Agmatine blocks ethanol-induced locomotor hyperactivity in male mice
Özden, Önder; Kayir, Hakan; Öztürk, Yusuf; Uzbay, Tayfun (Elsevier Science BV, 2011)Ethanol-induced locomotor activity is associated to rewarding effects of ethanol and ethanol dependence. Agmatine is a novel endogenous ligand at alpha(2)-adrenoceptors, imidazoline and N-methyl-D-aspartate (NMDA) receptors, ... -
Altered responses to calcium and trifluoperazine in K+-depolarized duodenum from alloxan diabetic rats
Contractile responses to calcium were examined in the K+-depolarized duodenum from normal and alloxan-diabetic rats. In addition, verapamil and trifluoperazine which are well-known calcium channel blocker and calmodulin ... -
Analgesic activity of Nepeta italica L.
Aydın, Süleyman; Demir, T; Öztürk, Yusuf; Başer, K. Hüsnü Can (John Wiley & Sons LTD, 1999)A screening study was performed on/by essential oils of Nepeta viscida Boiss and Nepeta italica L. using tail-flick and tail immersion (52.5 degrees C) methods, N. italica samples were collected from three different ... -
Antidepressant-like effect of gallic acid in mice: Dual involvement of serotonergic and catecholaminergic systems
Can, Özgür Devrim; Turan, Nazlı; Özkay, Ümide Demir; Öztürk, Yusuf (Pergamon-Elsevier Science LTD, 2017)Aims: This study was planned to examine the antidepressant potency of gallic acid (30 and 60 mg/kg), a phenolic acid widely distributed in nature, together with its possible underlying monoaminergic mechanisms. Main methods: ... -
Antihyperalgesic and antiallodynic effects of mianserin on diabetic neuropathic pain: A study on mechanism of action
Ucel, Umut İrfan; Can, Özgür Devrim; Özkay, Ümide Demir; Öztürk, Yusuf (Elsevier Science BV, 2015)This study used various experimental pain methods to investigate the effects of subacute mianserin administration on diabetes-induced neuropathic pain in rats. The effect of mianserin on hyperalgesia occurring in connection ... -
The Antioxidant Potency of Punica granatum L. Fruit Peel Reduces Cell Proliferation and Induces Apoptosis on Breast Cancer
Dikmen, Miriş; Öztürk, Nilgün; Öztürk, Yusuf (Mary Ann Liebert Inc, 2011)Pomegranate (Punica granatum L.) is known to possess pharmacological activities, such as antioxidant and anticancer. In this study, we evaluated the antioxidant potency of a methanolic pomegranate fruit peel extract (PPE) ... -
Antithrombotic effects of ethanol extract of Crataegus orientalis in the carrageenan-induced mice tail thrombosis model
Arslan, Rana; Bor, Zeynep; Bektaş, Nurcan; Meriçli, Ali Hikmet; Öztürk, Yusuf (Pergamon-Elsevier Science LTD, 2011)Introduction: Crataegus species (common name is Hawthorn) are medicinal plants, which have flavonoids, triterpene acids, proanthocyanidins, and organic acids as main constituents, used in the treatment of cardiovascular ... -
Attenuation of ethanol withdrawal syndrome by extract of Hypericum perforatum in Wistar rats
The effects of Hypericum perforatum (St John's wort) on ethanol withdrawal syndrome have been investigated in ethanol-dependent rats. Adult male Wistar rats were subjects. Ethanol (7.2% v/v) was given to rats by a liquid ... -
Basal and histamine-induced gastric acid secretion in alloxan diabetic rats
Özçelikay, A. T.; Altan, Vecdi Melih; Yıldızoğlu-Arı, N.; AltınKurt, Onur; Onur, F.; Öztürk, Yusuf (1993)1. 1. Effects of alloxan-induced diabetes on the rat gastric acid secretion were investigated using a number of biostatistical models described earlier. 2. 2. Histamine-induced gastric acid secretion was found to be decreased ... -
Beneficial effect of insulin on the decreased gastrointestinal ß-adrenergic responses in streptozotocin-diabetic rats: A contributing role of protein biosynthesis
The beneficial effect of insulin on the decreased gastrointestinal ß-adrenergic responses in experimentally diabetic rats has been reported. The effects of streptozotocin-induced diabetes and insulin on the isolated rat ... -
Calmodulin content and in vitro contractility of duodenum from streptozotocin-induced diabetic rats: Effects of insulin therapy and calmodulin antagonism
Öztürk, Yusuf; Aydın, Süleyman; Özçelikay, A. T.; Altan, Vecdi Melih; YıldızoğluArı, N (Elsevier Science BV, 1997)The effects of experimental diabetes and insulin treatment on the decreased reactivity of isolated rat duodenum to KCI and calmidazolium, a specific calmodulin antagonist, were examined. After 8 weeks of streptozotocin ... -
Comparison of antiproliferative and apoptotic effects of a novel proteasome inhibitor MLN2238 with bortezomib on K562 chronic myeloid leukemia cells
Engür, Selin; Dikmen, Miriş; Öztürk, Yusuf (Taylor & Francis LTD, 2016)Inhibition of the proteasome has emerged as a clinically effective anticancer therapeutic approach in recent years. Bortezomib (Velcade (R)) showed extremely high potency against a wide range of cancer cell lines. Ixazomib ... -
A Computer Experiment Model to Investigate the Effects of Drug Dosage in Animals, for Use in Pharmacological Education and Research
Babanlı, Ahmed; Güneş, Ali; Öztürk, Yusuf (Frame, 2011)The ACD-IDEA database, which was originally developed by the authors in 2004, is an ongoing compilation of existing data on the in vivo doses of compounds at which various responses in certain animal species have been ... -
Cytotoxic and inhibitory effects of pomegranate peel extract on proliferation of MCF-7 cells [Nar meyve kabugu ekstresi·ni·n mcf-7 hücre proli·ferasyonu üzeri·ne si·totoksi·k ve i·nhi·bi·tör etki·leri·]
Dikmen, Miriş; Öztürk, Nilgün; Öztürk, Yusuf (2008)The Pomegranate (Punica granatum L.) is a wonderful fruit which contains a wide variety of precious phytochemical compounds applicable in the fields of therapeutics and health care. Previous studies have demonstrated the ... -
Decreased Beta-Adrenergic Responses of Rat Small-Intestine Due to Non-Insulin-Dependent Diabetes
Öztürk, Yusuf; Yıldızoğulları, N; Özüarı, A; Özçelikay, At; Altan, Vecdi Melih (Elsevier Sci Ireland LTD, 1990)… -
Effect of benzothiazole/piperazine derivatives on intracerebroventricular streptozotocin-induced cognitive deficits
Özkay, Ümide Demir; Can, Özgür Devrim; Özkay, Yusuf; Öztürk, Yusuf (Polish Acad Sciences Inst Pharmacology, 2012)Background: In this study, benzothiazolc-piperazine compounds were synthesized by condensing the functional groups of donepezil (DNP), FK-960, and sabeluzole, which are known to have therapeutic potential against Alzheimer's ... -
Effect of lithium on gastro-intestinal complications in alloxan-diabetic rats
1. 1. Decreased ß-adrenergic and serotonergic responses have been reported in gastro-intestinal tract of experimentally diabetic rats. Effects of lithium on the decreased ß-adrenergic and serotonergic responsiveness of the ... -
Effect of phenolic acids on functions of rat aorta, vas deferens and on metabolic changes in streptozotocin-induced diabetes
Bektaş, Nurcan; Öztürk, Yusuf (Medknow Publications & Media Pvt LTD, 2012)Objectives: This study aimed to investigate the effects of antioxidant treatment on streptozotocin (STZ)-induced diabetic metabolic and smooth muscle (SM) complications in rats. Materials and Methods: Threeweeks after STZ ... -
The effect of simvastatin treatment on behavioral parameters, cognitive performance, and hippocampal morphology in rats fed a standard or a high-fat diet
Can, Özgür Devrim; Ulupınar, Emel; Özkay, Ümide Demir; Yegin, Bengi; Öztürk, Yusuf (Lippincott Williams & Wilkins, 2012)The aim of this study was to examine the effect of simvastatin (SMV), a 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitor, in rats fed with a standard or a high-fat diet (HFD) throughout the prenatal and the postnatal ... -
The effect of vanadyl treatment on vascular responsiveness of streptozotocin-diabetic rats
Özçelikay, A. T.; Pekiner, C.; Arı, N.; Öztürk, Yusuf; ÖzüArı, A.; Altan, Vecdi Melih (Springer-Verlag, 1994)Vanadyl sulphate has been demonstrated to possess insulin-like effects in streptozotocin (STZ) diabetic rats, including the normalization of hyperglycaemia and the prevention of diabetes-induced cardiac dysfunction. However, ...