Yazar "Özkay, Yusuf" için Makale Koleksiyonu listeleme
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Design, synthesis, and AChE inhibitory activity of new benzothiazole-piperazines
Özkay, Ümide Demir; Can, Özgür Devrim; Sağlık, Begüm Nurpelin; Çevik, Ulviye Acar; Levent, Serkan; Özkay, Yusuf; Atlı Eklioğlu, Özlem (Pergamon-Elsevier Science LTD, 2016)In the current study, 14 new benzothiazole-piperazine compounds were designed to meet the structural requirements of acetylcholine esterase (AChE) inhibitors. The target compounds were synthesised in three steps. Structures ... -
Effect of benzothiazole/piperazine derivatives on intracerebroventricular streptozotocin-induced cognitive deficits
Özkay, Ümide Demir; Can, Özgür Devrim; Özkay, Yusuf; Öztürk, Yusuf (Polish Acad Sciences Inst Pharmacology, 2012)Background: In this study, benzothiazolc-piperazine compounds were synthesized by condensing the functional groups of donepezil (DNP), FK-960, and sabeluzole, which are known to have therapeutic potential against Alzheimer's ... -
Synthesis and analgesic effects of 2-(2-carboxyphenylsulfanyl)-N-(4-substitutedphenyl)acetamide derivatives
Özkay, Ümide Demir; Özkay, Yusuf; Can, Özgür Devrim (Springer Birkhauser, 2011)This present study was undertaken to synthesize and investigate possible analgesic activities of some 2-(2-carboxyphenylsulfanyl)-N-(4-substitutedphenyl)acetamide derivatives that were designed by combining an analgesic ... -
Synthesis of new 1-phenyl-2-(4-substituted-piperazin-1-yl)-propanol derivatives and evaluation of their antidepressant-like effects
Özkay, Ümide Demir; Yurttaş, Leyla; Özkay, Yusuf; Ucel, Umut İrfan; Can, Özgür Devrim; Öztürk, Yusuf (Pharmaceutical Soc Korea, 2013)In this study, we synthesized eight novel 1-phenyl-2-(4-substituted-piperazin-1-yl)-propanol derivatives and evaluated their antidepressant-like activities. The chemical structures of the synthesised compounds were elucidated ...