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Toplam kayıt 132, listelenen: 34-53
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Composition of the essential oil of Cachrys alpina bieb.
(Allured Publ Corp, 2004)A hydrodistilled essential oil from fruits of Cachrysalpina,was analyzed by GUMS. Twenty-nine compounds representing 98% of the oil were identified with alpha-humulene (33.1%), p-cymene (9.3%). alpha-phellandrene (9.1%) ... -
A computer experiment model to investigate the effects of drug dosage in animals, for use in pharmacological education and research
(2011)The ACD-IDEA database, which was originally developed by the authors in 2004, is an ongoing compilation of existing data on the in vivo doses of compounds at which various responses in certain animal species have been ... -
A Computer Experiment Model to Investigate the Effects of Drug Dosage in Animals, for Use in Pharmacological Education and Research
(Frame, 2011)The ACD-IDEA database, which was originally developed by the authors in 2004, is an ongoing compilation of existing data on the in vivo doses of compounds at which various responses in certain animal species have been ... -
Cytotoxic and inhibitory effects of pomegranate peel extract on proliferation of MCF-7 cells [Nar meyve kabugu ekstresi·ni·n mcf-7 hücre proli·ferasyonu üzeri·ne si·totoksi·k ve i·nhi·bi·tör etki·leri·]
(2008)The Pomegranate (Punica granatum L.) is a wonderful fruit which contains a wide variety of precious phytochemical compounds applicable in the fields of therapeutics and health care. Previous studies have demonstrated the ... -
Decreased Beta-Adrenergic Responses of Rat Small-Intestine Due to Non-Insulin-Dependent Diabetes
(Elsevier Sci Ireland LTD, 1990)… -
Design, synthesis, and AChE inhibitory activity of new benzothiazole-piperazines
(Pergamon-Elsevier Science LTD, 2016)In the current study, 14 new benzothiazole-piperazine compounds were designed to meet the structural requirements of acetylcholine esterase (AChE) inhibitors. The target compounds were synthesised in three steps. Structures ... -
Dexketoprofen trometamol loaded solid lipid nanoparticles(SLNs): Formulation, in vitroand in vivoevaluation
(2020)Development, in vitroand in vivoevaluation of dexketoprofen trometamol (DT)-loaded nanosizeddrugdelivery system was aimed in this study. DT-loaded solid lipid nanoparticles (SLNs) were prepared using probe ... -
Dopamine D2 receptor gene-141C Insertion/Deletion polymorphism in Turkish schizophrenic patients
(Springer, 2011)Schizophrenia is a chronic and neuropsychiatric disease that affects about 0.5-1% of the world's population. An increase in dopamine and dopamine D2 receptor (DRD2) gene products has been well described in schizophrenic ... -
The Effect of Agomelatine Treatment on Diabetes-Induced Cognitive Impairments in Rats: Concomitant Alterations in the Hippocampal Neuron Numbers
(MDPI, 2018)Researches that are related to the central nervous system complications of diabetes have indicated higher incidence of cognitive disorders in patients. Since the variety of nootropic drugs used in clinics is limited and ... -
Effect of an aqueous distillate of Origanum onites L. on isolated rat fundus, duodenum and ileum: Evidence for the role of oxygenated monoterpenes
(Govi-Verlag Pharmazeutischer Verlag GMBH, 2005)The aqueous distillate of Origanum onites L. (Labiatae) was reported to have various ethnomedical uses including effects on the gastrointestinal tract. The effects of three different doses (0.1, 0.2 and 0.4 mL) of the ... -
Effect of benzothiazole/piperazine derivatives on intracerebroventricular streptozotocin-induced cognitive deficits
(Polish Acad Sciences Inst Pharmacology, 2012)Background: In this study, benzothiazolc-piperazine compounds were synthesized by condensing the functional groups of donepezil (DNP), FK-960, and sabeluzole, which are known to have therapeutic potential against Alzheimer's ... -
Effect of lithium on gastro-intestinal complications in alloxan-diabetic rats
(1992)1. 1. Decreased ß-adrenergic and serotonergic responses have been reported in gastro-intestinal tract of experimentally diabetic rats. Effects of lithium on the decreased ß-adrenergic and serotonergic responsiveness of the ... -
Effect of mianserin on streptozotocin-induced hyperglycemia and metabolic alterations in rats
(Çukurova University, Fac Medicine, 2017)Purpose: The aim of this study was to investigate possible effects of atypical antidepressant mianserin on glycemia levels and metabolic parameters of normoglycemic and diabetic rats Material and Methods: Effects of mianserin ... -
Effect of phenolic acids on functions of rat aorta, vas deferens and on metabolic changes in streptozotocin-induced diabetes
(Medknow Publications & Media Pvt LTD, 2012)Objectives: This study aimed to investigate the effects of antioxidant treatment on streptozotocin (STZ)-induced diabetic metabolic and smooth muscle (SM) complications in rats. Materials and Methods: Threeweeks after STZ ... -
The effect of simvastatin treatment on behavioral parameters, cognitive performance, and hippocampal morphology in rats fed a standard or a high-fat diet
(Lippincott Williams & Wilkins, 2012)The aim of this study was to examine the effect of simvastatin (SMV), a 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitor, in rats fed with a standard or a high-fat diet (HFD) throughout the prenatal and the postnatal ... -
Effect of subacute agomelatine treatment on painful diabetic neuropathy: involvement of catecholaminergic mechanisms
(Wiley, 2016)In this study, we investigated the effects of subacute agomelatine (40 and 80 mg/kg) administration on chronic hyperglycemia, metabolic parameters, and pain perception in streptozotocin-induced diabetic rats. Fasting blood ... -
The effect of vanadyl treatment on vascular responsiveness of streptozotocin-diabetic rats
(Springer-Verlag, 1994)Vanadyl sulphate has been demonstrated to possess insulin-like effects in streptozotocin (STZ) diabetic rats, including the normalization of hyperglycaemia and the prevention of diabetes-induced cardiac dysfunction. However, ... -
Effects of DNMT and HDAC Inhibitors (RG108 and Trichostatin A) on NGF-induced Neurite Outgrowth and Cellular Migration
(Asian Network Scientific Information-Ansinet, 2016)Neuropathological characteristics of neurodegenerative disorders are atrophy or loss of specific neurons in the specific brain areas. Small-molecule products like epigenetic drugs, which can activate silenced genes, regulate ... -
The Effects of Glyburide and Insulin on the Cardiac-Performance in Rats With Non-Insulin-Dependent Diabetes-Mellitus
(Pergamon-Elsevier Science LTD, 1993)1. The effects Of glyburide were studied on the myocardial contractile force and heart rate in the atria isolated from non-diabetic and non-insulin-dependent diabetic rats (diabetic). 2. In order to examine the myocardial ... -
Effects of hawthorn seed and pulp extracts on the central nervous system
(Informa Healthcare, 2010)Context: Investigating potential central nervous system (CNS) activities of Crataegus monogyna Jacq. (Rosaceae), hawthorn, fruit extracts. Objective: Evaluating CNS effects and analgesic activities of hawthorn fruit extracts ...