Makale Koleksiyonu by Institution Author "Öztürk, Yusuf"
Now showing items 21-40 of 52
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Effects of DNMT and HDAC Inhibitors (RG108 and Trichostatin A) on NGF-induced Neurite Outgrowth and Cellular Migration
Kaya-Tilki, Elif; Dikmen, Miriş; Öztürk, Yusuf (Asian Network Scientific Information-Ansinet, 2016)Neuropathological characteristics of neurodegenerative disorders are atrophy or loss of specific neurons in the specific brain areas. Small-molecule products like epigenetic drugs, which can activate silenced genes, regulate ... -
The Effects of Glyburide and Insulin on the Cardiac-Performance in Rats With Non-Insulin-Dependent Diabetes-Mellitus
Özüarı, A; Öztürk, Yusuf; Yıldızoğulları, N; Özçelikay, At; Altan, Vecdi Melih (Pergamon-Elsevier Science LTD, 1993)1. The effects Of glyburide were studied on the myocardial contractile force and heart rate in the atria isolated from non-diabetic and non-insulin-dependent diabetic rats (diabetic). 2. In order to examine the myocardial ... -
Effects of hawthorn seed and pulp extracts on the central nervous system
Can, Özgür Devrim; Özkay, Ümide Demir; Öztürk, Nilgün; Öztürk, Yusuf (Informa Healthcare, 2010)Context: Investigating potential central nervous system (CNS) activities of Crataegus monogyna Jacq. (Rosaceae), hawthorn, fruit extracts. Objective: Evaluating CNS effects and analgesic activities of hawthorn fruit extracts ... -
Effects of Insulin and St. John's Wort Treatments on Anxiety, Locomotory Activity, Depression, and Active Learning Parameters of Streptozotocin-Diabetic Rats
Can, Özgür Devrim; Öztürk, Yusuf; Özkay, Ümide Demir (Georg Thieme Verlag Kg, 2011)The aim of this work was to investigate the effects of St. John's Wort (SJW) extract treatment on behavioral changes arising in streptozotocin (STZ)-diabetic rats. Plus-maze, activity cage, modified forced swimming, and ... -
Effects of long-term agomelatine treatment on the cognitive performance and hippocampal plasticity of adult rats
Özkay, Ümide Demir; Soztutar, Erdem; Can, Özgür Devrim; Ucel, Umut İrfan; Öztürk, Yusuf; Ulupınar, Emel (Lippincott Williams & Wilkins, 2015)Agomelatine is an antidepressant with a distinct pharmacological mechanism of action as an MT1 and MT2 receptor agonist and as a 5-HT2C receptor antagonist. We evaluated the chronic effects of agomelatine administration ... -
Effects of phenolic acids on gastrointestinal smooth muscle complications in streptozotocine-induced diabetic rats
Bektaş, Nurcan; Öztürk, Yusuf (Tubitak Scientific & Technical Research Council Turkey, 2012)Aim: To identify the effects of antioxidants on gastrointestinal smooth muscle complications in 6-week streptozotocine (STZ)-induced diabetic rats. Materials and methods: The following steps were carried out: I. Three weeks ... -
Effects of Some 1,3,5-Trisubstitued-2-pyrazoline Derivatives on Depression and Anxiety Parameters of Mice
Can, Özgür Devrim; Özkay, Ümide Demir; Kaplancıklı, Zafer Asım; Öztürk, Yusuf (Pharmaceutical Soc Korea, 2009)The aim of the present study was examining the effects of some 1,3,5-trisubstituted-2-pyrazoline derivatives on depression, anxiety and spontaneous locomotor activity parameters of mice. None of the compounds was effective ... -
Effects of streptozotocin-induced diabetes and insulin on calcium responsiveness of the rat vas deferens
Öztürk, Yusuf; Aydın, Süleyman (Pergamon-Elsevier Science LTD, 2006)In the present study, effects of streptozotocin-induced diabetes and insulin treatment on the reactivity of rat vas deferens to KCl and calmidazolium, a calmodulin antagonist, were evaluated and calmodulin levels in vas ... -
Effects of treatment with St. John's Wort on blood glucose levels and pain perceptions of streptozotocin-diabetic rats
Can, Özgür Devrim; Öztürk, Yusuf; Öztürk, Nilgün; Sagratini, Gianni; Ricciutelli, Massimo; Vittori, Sauro; Maggi, Filippo (Elsevier Science BV, 2011)This present study was undertaken to examine treating effects of St. John's Wort (SJW) extract on nociceptive perception of STZ-diabetic animals based on its potential antidiabetic and antinociceptive activities. One week ... -
Escitalopram oxalate, a selective serotonin reuptake inhibitor, exhibits cytotoxic and apoptotic effects in glioma C6 cells
Dikmen, Miriş; Cantürk, Zerrin; Öztürk, Yusuf (Cambridge University Press, 2011)Objective: Various antidepressants, mainly tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs), have been reported to exhibit potent anticancer properties in different cancer cells. In this ... -
Evaluation of neuritogenic activity of cultivated, wild and commercial roots of Gentiana lutea L.
Mustafa, Ahmed M.; Caprioli, Giovanni; Dikmen, Miriş; Kaya, Elif; Maggi, Filippo; Sagratini, Gianni; Öztürk, Yusuf (Elsevier Science BV, 2015)Several natural products have been proven to prevent neurodegenerative disorders by potentiating the action of nerve growth factor (NGF). Among them, secoiridoids have recently attracted interest for their potential use ... -
Evaluation of the Wound Healing Potentials of Two Subspecies of Hypericum perforatum on Cultured NIH3T3 Fibroblasts
Dikmen, Miriş; Öztürk, Yusuf; Sagratini, Gianni; Ricciutelli, Massimo; Vittori, Sauro; Maggi, Filippo (Wiley-Blackwell, 2011)For centuries, Hypericum perforatum has been used in folk medicine to treat wounds. In the present study, the wound healing activities of extracts of H. perforatum ssp. perforatum (HPP) and H. perforatum ssp. veronense ... -
Extract of Hypericum perforatum blocks caffeine-induced locomotor activity in mice: A possible role of nitric oxide
Uzbay, I. Tayfun; Coşkun, Ilke; Kayir, Hakan; Öztürk, Nilgün; Öztürk, Yusuf (John Wiley & Sons LTD, 2007)The present study investigated the effects of HPE on caffeine-induced locomotor activity in mice. Caffeine (416 mg/kg) or saline were given to adult male Swiss-Webster mice, and the locomotor activity was immediately ... -
Extract of hypericum perforatum blocks nicotine-induced locomotor activitiy in mice
Sunulan çalışmada, farelerde nikotin ile indüklenen lokomotor aktivite üzerine Hiperikum perforatum ekstresinin etkileri incelenmiştir. Çalışmada denek olarak erişkin erkek Swiss-Webster türü fareler kullanıldı. Nikotin ... -
Extract of Hypericum perforatum blocks nicotine-induced locomotor activity in mice
Uzbay, T.; Kayir, H.; Coşkun, I.; Öztürk, Nilgün; Öztürk, Yusuf (2006)In the present study, the effects of Hypericum perforatum on nicotine-induced locomotor activity have been investigated in mice. Adult male Swiss-Webster mice were subjects. Nicotine (0.5, 1 and 2 mg/kg) and saline were ... -
An in vivo database model for pharmacological and physiological dosage for experimental animals
Güneş, Ali; Öztürk, Yusuf; Babanlı, Ahmad (Pergamon-Elsevier Science LTD, 2009)We developed a database compiling in vivo doses of compounds for various activities in certain animal species. The related database covers almost 100 years of experiments. The conceptual scheme of the database was created ... -
Increased Alpha(1)-Adrenergic Responsiveness of Alloxan-Diabetic Rat Atria - Effects of Insulin Therapy and Thyroidectomy
Lafçıerol, D; Altan, Vecdi Melih; Öztürk, Yusuf (Pergamon-Elsevier Science LTD, 1994)1. Experimental models of diabetes are increasingly used for the investigation of cardiovascular complications as well as other complications due to diabetes mellitus. However, animal models have been used in relatively ... -
Inhibition of C6 Glioma Cell Proliferation by Au(III) and Pt(II) Complexes of 1,10-Phenanthroline-5,6-dione
Dikmen, Miriş; Benkli, Kadriye; Öztürk, Yusuf (Asian Journal Of Chemistry, 2011)In this study, we studied the antiproliferative effecs of Au(III) and Pt(II) metal complexes of 1,10-phenanthroline-5,6-dione and cisplatin on rat glioma C6 cells. The antiproliferative effects were evaluated by MTT ... -
Inhibitory effects of carvacrol on DMBA induced pulmonary tumorigenesis in rats
Essential oils of various plant species rich in carvacrol have several ethnomedical uses for various diseases in Turkey. Carvacrol, which was obtained by fractional distillation of Origanun onites L essential oil was tested ... -
Investigation of the Apoptotic Effect of Curcumin in Human Leukemia HL-60 Cells by Using Flow Cytometry
Dikmen, Miriş; Cantürk, Zerrin; Öztürk, Yusuf; Tunalı, Yağmur (Mary Ann Liebert, Inc, 2010)Curcumin (diferuloylmethane), the major yellow pigment isolated from the turmeric (Curcuma longa), has received much attention due to several biological properties. Curcumin exhibits a variety of pharmacological effects ...