Başlık için Biyokimya Anabilim Dalı listeleme
Toplam kayıt 103, listelenen: 64-83
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Inhibition of Human Serum Paraoxonase-I with Antimycotic Drugs: In Vitro and In Silico Studies
(Humana Press Inc., 2019)Drugs show their pharmacological effects by inhibiting or activating enzymes. Therefore, enzyme inhibitors have an essential place in the drug design for numerous different sorts of diseases, i.e., cardiovascular, cancer, ... -
Inhibition properties of some flavonoids on carbonic anhydrase I and II isoenzymes purified from human erythrocytes
(Wiley, 2017)Carbonic anhydrases (CAs, E.C.4.2.1.1) play a critical role in many important physiological events and treatment of some diseases. Flavonoids or phenolic compounds have been discovered as novel CAs inhibitors instead of ... -
Inhibitory effect of Calamintha nepeta subsp glandulosa essential oil on lipoxygenase
(Walter De Gruyter GMBH, 2011)Objective: Scavenging of free radicals and inhibition of lipoxygenase are important target in the treatment of a variety of inflammatory diseases. Calamintha nepeta (L.) Savi subsp. glandulosa (Req.) P.W. Ball of Lamiaceae ... -
Inhibitory Effects of Usnic and Carnosic Acid on Some Metabolic Enzymes: An in vitro Study
(Bentham Science Publ LTD, 2019)Background: Natural products arc produced via primary and secondary metabolism in different organisms. The compounds obtained via secondary metabolism are not essential for the survival of the organism, but they can have ... -
The interactions of cephalosporins on polyol pathway enzymes from sheep kidney
(Taylor & Francis LTD, 2018)Context: Cephalosporins are derived from the fungus Acremonium. Due to their strong bactericidal ability, these drugs have to a wide usage in medicine.Objective: An investigation of the effects on sheep renal aldose reductase ... -
Koyun Karaciğerinden Alkol Dehidrogenaz: Saflaştırma, Karakterizasyon, ve Bazı Antibiyotiklerin Etkileri
(2017)Alkol dehidrogenaz (ADH), her bir alt biriminin bir Zn2+ metal içeren katalitik alana ve bir kofaktör bağlama alanına sahip olduğu dimerik bir enzimdir. Bu enzim, alkolü, aldehide dönüştürür. Bu makale koyun karaciğerinden ... -
Lipid profle and levels of homocysteine, leptin, fbrinogen and C-reactive protein in hyperthyroid patients before and after treatment
(2010)Amaç: Bu çalışma hipertiroidizmli hastalarda tiroid hormonlarının lipid proflini, eritrosit sedimentasyon hızını (ESR), serum total homosistein (t-hcy), leptin, fbrinojen ve C-reaktif protein (CRP) düzeylerini etkileyip ... -
Mechanism of capsaicin inhibition of aldose reductase activity
(Wiley, 2017)Aldose reductase (AR) inhibitors play a vital importance as a potential therapeutic and preventive medicine when it comes to hyperglycemia associated diabetic complications. Additionally, capsaicin is used as a food additive ... -
Modification of intracellular free calcium in cultured F2408 embryo fibroblasts by 3-sub substituted-2-thiohydantoin derivatives
(Wiley, 2004)3-substituted-2-thiohydantoin derivatives were synthesized and their Structures elucidated by IR, H-1-NMR spectroscopy and elemental analysis. The cytotoxicity of the 2-thiohydantoin derivatives to rat embryo fibroblasts ... -
NO levels in diabetes mellitus: Effects of l-NAME and insulin on LCAT, Na+/K+ ATPase activity and lipid profile
(Elsevier Ltd, 2011)Objectives: Diabetes mellitus (DM) is a chronic disease and one of the most important health problems. Several factors may be responsible for the complications of diabetes mellitus including alterations in the activities ... -
Novel morpholine dithiocarbamate derivatives induces apoptosis in C6 glioma
(Wiley-Blackwell, 2016)… -
Oxidative and inflammatory status and HDL functions of obese pre and post menopausal women
(Walter De Gruyter GMBH, 2014)Objective: Obesity and age related vascular changes coupled with the effect of estrogen withdrawal increases predisposition to atherosclerosis in postmenopausal women. But the functions of high density lipoprotein (HDL) ... -
Oxidative stress and mRNA expression of acetylcholinesterase in the leukocytes of ischemic patients
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)Background: Pathogenesis of ischemic brain injury is occurred by crucial metabolic reasons. For instance, oxidative stress from free radical generation is causing to the thrombotic cerebrovascular stroke. In this case, the ... -
Phenolic compounds inhibit the aldose reductase enzyme from the sheep kidney
(Wiley, 2017)Aldose reductase (AR) is the key enzyme for the polyol pathway and responsible for sorbitol accumulation during the hyperglycemia. The present article focuses on the role of phenol, pyrogallol, hydroquinone, resorcinol, ... -
Phenolic compounds: The inhibition effect on polyol pathway enzymes
(Elsevier Ireland LTD, 2017)The polyol pathway called as sorbitol way is a small part of glycose metabolism. The pathway is regarded as an important element in the pathogenesis of various diabetic complications in individuals with diabetes mellitus. ... -
Phytase from Weissella halotolerans: purification, partial characterisation and the effect of some metals
(Taylor & Francis Inc, 2017)In the study, phytase was purified in three simple steps comprising ammonium sulphate precipitation, anion exchange and gel filtration chromatography from Weissella halotolerans. The enzyme was obtained with a specific ... -
Preperation and in vitro characterization of epsilon-viniferine and vincristine sulfate loaded PLGA-b-PEG nanoparticles
(Lippincott Williams & Wilkins, 2015)… -
Protective effect of combined CoQ10 and quercetin treatment on radiation-mediated damage in rats
(Taylor & Francis LTD, 2009)… -
Protective role of melatonin and coenzyme Q(10) in ochratoxin a toxicity in rat liver and kidney
(Sage Publications Inc, 2007)Melatonin ( MEL) and coenzyme Q10 ( CoQ10) both display antioxidant and free radical scavenger properties. In the present study, the effect of MEL and CoQ10 on the oxidative stress and fibrosis induced by ochratoxin A ( ...