Güncel Gönderiler: Makale Koleksiyonu
Toplam kayıt 115, listelenen: 101-115
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Chemometrically assisted optimization and validation of a new HPLC method for the determination of paliperidone in pharmaceuticals
(Taylor & Francis Inc, 2018)Paliperidone is an antipsychotic drug, which is used for the acute and maintenance treatment of schizophrenia. In this study, a new method was developed for the determination of Paliperidone in its extended-release tablets. ... -
The Effects of Vasoactive Intestinal Peptide on Dura Mater Nitric Oxide Levels and Vessel-Contraction Responses in Sympathectomized Rats
(Humana Press Inc, 2010)Nitric oxide (NO) and neurogenic inflammation in dura mater due to nociceptor activation has been implicated for pathophysiology of primary headache disorders. Development of migraine has also been observed in patients ... -
Comparative study of different chemistries and particle properties, high-performance liquid chromatography stationary phases in separation of escitalopram oxalate and its impurities in different pharmaceutical dosage forms
(Wiley-V C H Verlag GMBH, 2019)The liquid chromatographic separation performance of 12 different columns was evaluated for the estimation of the escitalopram oxalate and six of its impurities in different pharmaceutical formulations. All columns exhibited ... -
A novel RP-HPLC method for simultaneous determination of potassium sorbate and sodium benzoate in soft drinks using C-18-bonded monolithic silica column
(Wiley Periodicals, Inc, 2011)Potassium sorbate and sodium benzoate are food additives that are generally employed for prevention of food spoilage originating from bacteria, molds or yeasts. Although these compounds were generally recognized as safe ... -
Comparative Study for Direct Evaluation of Montelukast Sodium in Tablet Dosage Form By Multiple Analytical Methodologies
(Editura Acad Romane, 2017)Different non-sophisticated analytical methods consisting of Ultraviolet Spectrometry (UV), Osteryoung Square Wave Voltammetry (OSWV) and flow injection analysis (FIA) were developed, validated according to ICH Q2 (R) 1 ... -
Determination of Ticlopidine in Pharmaceutical Tablets by Flow Injection Analysis Using UV-Detection
(Taylor & Francis Inc, 2008)A precise and accurate flow injection analysis method for the quantification of ticlopidine in pharmaceuticals is described. An aqueous carrier stream, which was entirely prepared with water was chosen for the flow injection ... -
Reversed-Phase HPLC Analysis of Levetiracetam in Tablets Using Monolithic and Conventional C18 Silica Columns
(Aoac Int, 2010)Development and validation of an RP-HPLC method for determination of levetiracetam in pharmaceutical tablets is described. The separation and quantification of levetiracetam and caffeine (internal standard) were performed ... -
Pharmacological and Toxicological Screening of Novel Benzimidazole-Morpholine Derivatives as Dual-Acting Inhibitors
(MDPI, 2017)The aim of this study was to investigate acetylcholinesterase (AChE), monoamine oxidase A (MAO-A), monoamine oxidase B (MAO-B), cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzyme inhibitory, and antimicrobial ... -
Rapid determination of free anthocyanins in foodstuffs using high performance liquid chromatography
(Elsevier Sci LTD, 2012)Anthocyanins constitute a major group of natural pigments, and they are responsible for the colours of fruits and vegetables. A rapid and feasible assay procedure for the determination of free forms of the six most abundant ... -
Analysis of Acrylamide in Traditional and Nontraditional Foods in Turkey Using Hplc-Dad With Spe Cleanup
(Taylor & Francis Inc, 2014)Acrylamide is a heat-generated food toxicant, which exists in various foodstuffs such as potato chips, biscuits, and coffee. It has been demonstrated that acrylamide possesses some neurotoxic and carcinogenic effects and ... -
Development of a validated HPLC method for simultaneous determination of olanzapine and aripiprazole in human plasma
(Marmara University, 2018)A simple and rapid HPLC method was developed and validated for simultaneous determination of two antipsychotic drugs, olanzapine and aripiprazole, in spiked human plasma. Optimization studies were performed using experimental ... -
Determination of Ochratoxin A in Turkish Wines
(Food & Drug Adminstration, 2009)A validated, simple and highly sensitive analytical method was described for the determination of Ochratoxin A (OTA) in various wines produced in Turkey. OTA concentrations of 25 wine samples were examined using high ... -
Development of a validated high-performance liquid chromatographic method for the determination of Lurasidone in pharmaceuticals
(Marmara University, Fac Pharmacy, 2017)A new, rapid and simple HPLC method for determination of Lurasidone in its tablets has been developed and validated. Lurasidone and internal standard (Chlorpromazine) was separated on a Zorbax XDB C8 column (4.6 x 50 mm, ... -
Determination of piribedil in human serum, urine and pharmaceutical dosage form by LC-DAD
(Springer Heidelberg, 2008)A rapid, selective and sensitive reversed-phase liquid chromatographic (LC) method was developed for the determination of piribedil in human serum, urine and pharmaceutical dosage form. LC analysis was carried out using ... -
Simultaneous Determination of Substance P and CGRP in Rat Brainstem Tissue Using LC-ESI-MS/MS Method
(Bentham Science Publ LTD, 2018)Background: Substance P and CGRP are neuropeptides that belong to the thachykinin and calcitonin family, respectively. They play an important role in neuropathic pain development and regulation. Methods: In this study, ...