Güncel Gönderiler: Scopus İndeksli Yayınlar Koleksiyonu
Toplam kayıt 8325, listelenen: 341-360
-
Levocetirizine Dihydrochloride-Loaded Chitosan Nanoparticles: Formulation and in Vitro Evaluation
(Turkish Pharmacists Assoc, 2020)Objectives: the aim of the present study was to formulate levocetirizine hydrochloride (LCD)-loaded chitosan nanoparticles at submicron level with high entrapment efficiency and prolonged effect for optimizing the plasma ... -
Synthesis, structure elucidation, and in vitro pharmacological evaluation of novel polyfluoro substituted pyrazoline type sulfonamides as multi-target agents for inhibition of acetylcholinesterase and carbonic anhydrase I and II enzymes
(Academic Press Inc Elsevier Science, 2020)A novel series of 4-(3-(difluorophenyl)-5-(dimethoxyphenyl)-4,5-dihydropyrazol-1-yl)benzenesulfonamides 1-8 were designed since sulfonamide and pyrazoline pharmacophores draw great attention in novel drug design due to ... -
Benzenesulfonamide derivatives containing imine and amine groups: Inhibition on human paraoxonase and molecular docking studies
(Elsevier, 2020)Sulfonamides known as inhibitors of many metabolic enzymes have been widely used as antimicrobial drugs for a long time. in the present study, we investigated in vitro inhibitory activities of benzenesulfonamide derivatives ... -
Phenolic profile and antioxidant, acetylcholinesterase, and tyrosinase inhibitor activities of Jurinea tzar-ferdinandii Davidov, an endemic plant of the Balkans
(Ms-Editions, 2020)The methanol extract of the Balkan endemic species Jurinea tzar-ferdinandii Davidov demonstrated weak antioxidant activity against DPPH center dot and ABTS+center dot and low inhibitory potential against acetylcholinesterase ... -
Antiamnesic effects of tofisopam against scopolamine-induced cognitive impairments in rats
(Pergamon-Elsevier Science Ltd, 2020)In this study, we investigated the potential therapeutic effects of tofisopam, a 2,3-benzodiazepine derivative anxiolytic, on cognitive deficits in rats with scopolamine-induced amnesia. Cognitive performance of the rats ... -
State predation in historical perspective: the case of Ottoman musadere practice during 1695-1839
(Springer, 2020)This paper studies the practice of Musadere in the Ottoman Empire. Musadere refers to the expropriation of elites-often tax farmers or administrators-by the Sultan. This practice is interesting from both political economy ... -
A Social Network Analysis of the July 15 Coup Attempt: Social Resistance, Network Patterns, and Collective Discourse
(Ahmet Yesevi Univ, 2020)Many aspects of the July 15 failed coup attempt were significant and induded social resistance, community formation and network patterns, collective discourse, perception management and power of the new media. Based on ... -
Insecticidal and Biting Deterrent Activities of Magnolia grandiflora Essential Oils and Selected Pure Compounds against Aedes aegypti
(Mdpi, 2020)In our natural products screening program for mosquitoes, we tested essential oils extracted from different plant parts of Magnolia grandiflora L. for their insecticidal and biting deterrent activities against Aedes aegypti. ... -
An in vitro investigation of genotoxic effects of dexketoprofen trometamol on healthy human lymphocytes
(Taylor & Francis Ltd, 2020)Non-steroidal anti-inflammatory drugs are drugs with analgesic, antipyretic, and anti-inflammatory effects. This study uses in vitro methods to investigate the potential and unknown genotoxic effects of dexketoprofen ... -
Caffeoylquinic Acids, Cytotoxic, Antioxidant, Acetylcholinesterase and Tyrosinase Enzyme Inhibitory Activities of Six Inula Species from Bulgaria
(Wiley-V C H Verlag Gmbh, 2020)Chlorogenic (5-CQA), 1,5-, 3,5-, 4,5- and 3,4-dicaffeoylquinic (DCQA) acids were identified and quantified in the methanol extracts of Inula oculus-christi L., I. bifrons L., I. aschersoniana Janka var. aschersoniana, I. ... -
Synthesis and docking study of benzimidazole-triazolothiadiazine hybrids as aromatase inhibitors
(Wiley-V C H Verlag Gmbh, 2020)Aromatase is involved in the biosynthesis of estrogen and thus is a critical target for breast cancer. in this study, to identify new aromatase enzyme inhibitors, seven 3-[4-(5-methyl-1H-benzo[d]imidazol-2-yl)phenyl]-6-( ... -
Antimicrobial, anticholinesterase evaluation and chemical characterization of essential oil Phlomis kurdica Rech. fil. Growing in Turkey
(Taylor & Francis Inc, 2020)The Phlomis kurdica Rech.fil. (Lamiaceae) essential oil was investigated for its chemical constituents and in vitro biological activities. Volatile components were characterized, antimicrobial and anticholinesterase ... -
Calcium channel blockers: molecular docking and inhibition studies on carbonic anhydrase I and II isoenzymes
(Taylor & Francis Inc, 9999)Carbonic anhydrases (CAs) are potent dehydration of carbonic acid and catalyst of the reversible hydration of carbon dioxide. Here, CA I and CA II was purified from human erythrocytes using the simple chromatographic method ... -
Does disability matter in counselling? Views of counsellors with visual disabilities and their clients
(Routledge Journals, Taylor & Francis Ltd, 2020)In this study we investigated the case of disability from the perspective of counsellors with visual disability (CWVD) and their clients by focusing on the counselling skills of CWVD, the relationships with their clients, ... -
Development of self-care behaviours in counsellors-in-training through an experiential self-care course: an action research
(Routledge Journals, Taylor & Francis Ltd, 9999)The purpose of this study was to evaluate changes in the self-care behaviours of counsellors-in-training who participated in a 12-week experiential "Self-Care Course for Counsellors-SCC". the study was conducted through ... -
Carbonic anhydrase, obstructive sleep apnea and hypertension: Effects of intervention
(Wiley, 2020)Whole blood carbonic anhydrase activity (CAa) is increased in patients with obstructive sleep apnea (OSA). Our study investigated the influence of positive airway pressure (PAP) or CA inhibitor acetazolamide (ACT) therapy ... -
A novel lanthanide-chelate based molecularly imprinted cryogel for purification of hemoglobin from blood serum: An alternative method for thalassemia diagnosis
(Elsevier Sci Ltd, 2020)Purification and analyzing of proteins is an essential means for understanding their function and diseases associated with their lack or defect. in this research, a new lanthanide-chelate based molecularly imprinted polymer ... -
Physicochemical characterization and pharmacokinetic evaluation of rosuvastatin calcium incorporated solid lipid nanoparticles
(Elsevier, 2020)Rosuvastatin calcium (RCa) is a very efficient antihyperlipidemic agent, however, being a BCS class II drug, results in poor oral bioavailability. the present study focused on the enhancement of oral bioavailability of RCa ... -
Catecholaminergic and opioidergic system mediated effects of reboxetine on diabetic neuropathic pain
(Springer, 2020)Rationale Current data indicate that the noradrenergic system plays a critical role in neuropathic pain treatment. Notably, drugs that directly affect this system may have curative potential in neuropathy-associated pain. ... -
Emotional and social competence in the aestheticization of labor in the restaurant industry
(Emerald Group Publishing Ltd, 2020)Purpose the purpose of this paper is to provide guidance regarding the satisfaction of customer needs in the competitive restaurant industry. Restaurants have seen a transformation in employees' labor, changing from primarily ...
