Kurum Yazarı "Kutlu, Hatice Mehtap" Scopus İndeksli Yayınlar Koleksiyonu İçin Listeleme
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Acrylamide exerts its cytotoxicity in NIH/3T3 fibroblast cells by apoptosis
Şahintürk, Varol; Kacar, Sedat; Vejselova, Djanan; Kutlu, Hatice Mehtap (Sage Publications Inc, 2018)Objective: Acrylamide is a chemical utilized in various industries, and many studies have demonstrated its toxicity. The NIH/3T3 mouse embryonic cell line is the standard cell line of fibroblasts, which have a pivotal role ... -
Acrylamide-derived cytotoxic, anti-proliferative, and apoptotic effects on A549 cells
Kacar, S.; Vejselova, Djanan; Kutlu, Hatice Mehtap; Şahintürk, V. (SAGE Publications LTD, 2018)Background: Acrylamide is a very common compound even reaching up to our daily foods. It has been studied in a wealth of cell lines on which it proved to have various toxic effects. Among these cell lines, human lung ... -
Antiproliferative and apoptotic effects of vanadyl sulphate on H-Ras transformed 5rp7 cells
Kutlu, Hatice Mehtap; Vejselova, Djanan (Cambridge University Press, 2014)[No abstract available] -
The apoptotic and genomic studies on A549 cell line induced by silver nitrate
Kaplan, Ayşe; Çiftçi, Gülsen Akalın; Kutlu, Hatice Mehtap (SAGE Publications LTD, 2017)Lung cancer is the leading cause of male cancer deaths worldwide. Metal-based anticancer drugs have evolved significantly during the past decades. Recently, silver ions have been investigated for their anticancer effects. ... -
The Apoptotic Effects of Escin in The H-Ras Transformed 5RP7 Cell Line
Güney, G.; Kutlu, Hatice Mehtap; İşcan, A. (Wiley, 2013)Extracts of Aesculus hippocastanum L. (horse chestnut) seed have been used in the treatment of chronic venous insufficiency, edema and hemorrhoids. Most of the beneficial effects of horse chestnut are attributed to its ... -
Biochemial properties of glutathione peroxidase m Gammarus pulex
Kutlu, Hatice Mehtap; Susuz, F (Springer, 2004)… -
Biochemical characterization of glutathion-S-transferase and effects of lead acetate in Gammarus pulex
Kutlu, Hatice Mehtap; Susuz, F. (2000)Glutathione transferases (GST s; EC. 2.5.1.18) are a family of multifunctional proteins that catalyze the conjugation of GSH to the electrophilic centre of a large number of active molecules. A great number of drugs, ... -
Biochemical profile of those who are subject to the industrial wastes of battery factories in Eskisehir
Kutlu, Hatice Mehtap; Uslu, S (Mbr Press Inc, 1999)Lead poisoning is one of the most important which among professional diseases. The industries which causes environmental lead pollution are lead mining, lead metalurgy, battery manufacturing, ship parts, cristal glass ... -
Comparative Study on Induction of Apoptosis in A549 Human Lung Adenocarcinoma Cells by C2 Ceramide or Ceranib-2
Kuş, Gökhan; Kutlu, Hatice Mehtap; Vejselova, Djanan; Çömlekçi, Emre (Zoological Soc Pakistan, 2017)Investigation of ceramide and ceramidases on cancer therapy had become popular in recent years. Ceramide is a metabolite in sphingolipid pathway of the cells that has an ability to promote cell death in tumor cells when ... -
A comparative study on the therapeutic effects of Silymarin and Silymarin-Loaded Solid Lipid Nanoparticles on D-GaIN/TNF-alpha-induced Liver Damage in Balb/c Mice
Cengiz, Mustafa; Kutlu, Hatice Mehtap; Burukoğlu, Dilek; Ayhanci, Adnan (Pergamon-Elsevier Science LTD, 2015)Nanostructure-mediated drug delivery is known to have a potential to improve drug bioavailability, apart from fostering release deviation of drug molecules and enabling precision drug targeting. Solid lipid nanoparticles ... -
Cytotoxic and apoptotic effects of ceranib-2 offering potential for a new antineoplastic agent in the treatment of cancer cells
Vejselova, Djanan; Kutlu, Hatice Mehtap; Kuş, Gökhan; Kabadere, Selda; Uyar, Ruhi (Tubitak Scientific & Technical Research Council Turkey, 2014)Fibrocarcinomas are malignant tumours that originate in mesenchymal cells. The tumours typically form in the presence of connective tissue and are of key consideration when assessing research priorities for future healthcare ... -
Cytotoxic, anti-proliferative and apoptotic effects of silver nitrate against H-ras transformed 5RP7
Kaplan, Ayşe; Çiftçi, Gülsen Akalın; Kutlu, Hatice Mehtap (Springer, 2016)Metal based drugs have successfully been used in both the detection and treatment of different disease states. The antibacterial features of metal ion silver are well documented. Most recently, metal ion silver has been ... -
delta-Aminolevulinic acid dehydratase of Haloarcula argentinensis isolated from Tuz Lake in Turkey
Korcan, S. Elif; Mutlu, M. Burçin; Ciğerci, I. Hakkı; Güven, Kıymet; Konuk, Muhsin; Kutlu, Hatice Mehtap (Springer, 2010)The delta-aminolevulinic acid dehydratase (ALAD) enzyme of a novel record for Turkish microbial flora was studied. The isolate I-113 was obtained from Tuz Lake in Turkey and identified as Haloarcula argentinensis. The ALAD ... -
Effect of Copper on the Body Wall Structures of the Medicinal Leech Hirudo Verbana Carena, 1820
Kutlu, Hatice Mehtap; Tanatmış, Mustafa; İşcan, Arzu; Ertorun, Nesil; Calim, Mert (Parlar Scientific Publications (PSP), 2010)In this study, acute toxicity effects of copper on the fibroblast cells and body wall structures of medicinal leech (Hirudo verbana) were characterized by using light microscope and transmission electron microscope (TEM). ... -
Effects of caffeic acid incorporated into solid lipid nanoparticles in cancer cells
Kutlu, Hatice Mehtap; Güney, Gamze; İşcan, A.; Genç, Lütfi (2011)Nanotechnology has great potential to make an important role in prevention of cancer, detection, diagnosis, imaging and treatment. Solid lipid nanoparticles (SLNs) have been introduced as an alternative drug carrier system. ... -
Effects of exogenous metallothionein against thallium-induced oxidative stress in rat liver
Kılıç, Gözde Aydoğan; Kutlu, Hatice Mehtap (Pergamon-Elsevier Science LTD, 2010)Metallothionein (MT) is a low-molecular weight sulfur-rich protein that plays role in metal homeostasis/detoxification and radical scavenging. The following study investigated the ability of exogenous MT to protect against ... -
Effects of lead and some ions on the activity of Glutathione reductase in Gammarus pulex
Kutlu, Hatice Mehtap; Poyraz, I.; Özata, Ahmet (2000)Gammarus pulex, a member of the Amphipoda, has been commonly used as a test organism in environmental toxicology in recent years. Glutathione reductase is an enzyme that is very important in effective detoxification of ... -
Effects of Lead as an Environmental Pollutant on EROD Enzyme in Gammarus pulex (L.) (Crustacea: Amphipoda)
Kutlu, Hatice Mehtap; Susuz, F. (Springer New York, 2004)[No abstract available] -
Effects of lead on the activity of 6-aminolevulinic acid dehydratase in Gammarus pulex
Kutlu, Hatice Mehtap; Sümer, S (Springer Verlag, 1998)…