Kurum Yazarı "Arslan, Rana" Scopus İndeksli Yayınlar Koleksiyonu İçin Listeleme
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Analgesic and antispasmodic activities of 2-(2-nitro-phenyl)-1 H-benzimidazole 5-carboxylic acid: Evidence for the importance of the 2-(o-substituted phenyl) group
Aydın, Süleyman; Arslan, Rana; Can, Özgür Devrim (2003)Benzimidazole 5-carboxylic acid derivatives were investigated for analgesic activity in this study. Of the benzimidazole compounds tested, 2-(2-nitro-phenyl)-1 H-benzimidazole 5-carboxylic acid showed remarkable naloxone ... -
Antinociceptive activity of methanol extract of fruits of Capparis ovata in mice
Arslan, Rana; Bektaş, Nurcan; Öztürk, Yusuf (Elsevier Ireland LTD, 2010)Ethnopharmacological relevance: Capparis ovata Desf. and Capparis spinosa L have wide natural distribution in Turkey and they are consumed in pickled form. Flower buds, root bark, and fruits of the plant are used in folk ... -
Antinociceptive effect of methanol extract of Capparis ovata in mice
Arslan, Rana; Bektaş, Nurcan (Taylor & Francis LTD, 2010)Context: Capparis ovata Desf. (Capparaceae) grows widely in Turkey. Flower buds and fruits of the plant are used in folk medicine for their analgesic, antirheumatismal, and diuretic effects. Objective:This study evaluated ... -
Antinociceptive, antiinflammatory, and antioxidant activities of the ethanol extract of Crataegus orientalis leaves
Bor, Zeynep; Arslan, Rana; Bektaş, Nurcan; Pirildar, Sevda; Dönmez, Ali Aslan (Tubitak Scientific & Technical Research Council Turkey, 2012)Aim: To determine the in vitro antioxidant activity and to investigate the possible antinociceptive and antiinflammatory effects of the ethanol extract of Crataegus orientalis leaves. The medicinal use of extracts prepared ... -
Antithrombotic effects of ethanol extract of Crataegus orientalis in the carrageenan-induced mice tail thrombosis model
Arslan, Rana; Bor, Zeynep; Bektaş, Nurcan; Meriçli, Ali Hikmet; Öztürk, Yusuf (Pergamon-Elsevier Science LTD, 2011)Introduction: Crataegus species (common name is Hawthorn) are medicinal plants, which have flavonoids, triterpene acids, proanthocyanidins, and organic acids as main constituents, used in the treatment of cardiovascular ... -
Cannabinoid system involves in the analgesic effect of protocatechuic acid
Dikmen, D. Y.; Okcay, Y.; Arslan, Rana; Bektaş, Nurcan (Springer, 2019)Background: Protocatechuic acid is an antioxidant which is shown to have analgesic activity in limited studies. However, the mechanisms of action remain unclear. Objectives: It is aimed to investigate the possible contribution ... -
The Centrally-Mediated Mechanisms of Action of Ferulic Acid-Induced Antinociception
Bektaş, Nurcan; Arslan, Rana (Marmara University, Fac Medicine, 2016)This study aimed to investigate the central antinociceptive effects of ferulic acid, a common phenolic compound found in various medicinal plants used for pain relief, and the contribution of cholinergic, serotonergic, ... -
Chitosan gel formulations containing egg yolk oil and epidermal growth factor for dermal burn treatment
Yenilmez, Evrim; Başaran, E.; Arslan, Rana; Berkman, Murat Sami; Güven, Umay Merve; Baycu, C.; Yazan, Yasemin (Govi-Verlag Pharmazeutischer Verlag GMBH, 2015)In the present study chitosan based gel formulations containing Egg Yolk Oil (EYO) and Epidermal Growth Factor (EGF) were formulated successfully aiming at enhanced topical treatment of dermal burns the combination of ... -
Dexketoprofen trometamol loaded solid lipid nanoparticles(SLNs): Formulation, in vitroand in vivoevaluation
Anadolu Üniversitesi, Eczacılık Fakültesi; 0000-0001-9596-0538; 0000-0002-7979-0089; 0000-0002-8041-6844; 0000-0001-9747-8307; 0000-0002-7492-1668; Öztürk, A. Alper; Yenilmez, Evrim; Arslan, Rana; Şenel, Behiye; Yazan, Yasemin (2020)Development, in vitroand in vivoevaluation of dexketoprofen trometamol (DT)-loaded nanosizeddrugdelivery system was aimed in this study. DT-loaded solid lipid nanoparticles (SLNs) were prepared using probe ... -
Dexketoprofen trometamol-loaded kollidon® SR and eudragit® RS 100 polymeric nanoparticles: Formulation and in vitro-in vivo evaluation
Öztürk, Ahmet Alper; Yenilmez, Evrim; Arslan, Rana; Şenel, Behiye; Yazan, Yasemin (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2017)Development and in vivo/in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized, controlled release drug delivery system was aimed in this study.. DT-loaded Kollidon® SR (KSR) and Eudragit® RS 100 (ERS) ... -
Effects of Hypericum calycinum L extract on the central nervous system in mice
Öztürk, Yusuf; Aydın, Süleyman; Arslan, Rana; Başer, K. Hüsnü Can; Berberoğlu, H (John Wiley & Sons LTD, 1996)Hypericum species have been used as herbal remedies for the therapy of various neurological disorders. In the present study, the effects of Hypericum calycinum on the central nervous system were investigated using various ... -
Effects of Hypericum perforatum L and Hypericum calycinum L extracts on the central nervous system in mice
Öztürk, Yusuf; Aydın, Süleyman; Arslan, Rana; Başer, K. Hüsnü Can; Berberoğlu, H (Gustav Fischer Verlag, 1996)Hypericum species have been used as herbal remedies for the therapy of various diseases since ancient times. It has been reported that Hypericum perforatum is a useful herbal remedy for the treatment of neurological disorders ... -
Evaluation of the Antidiabetic Property of Capparis Ovata Desf. Var. Palaestina Zoh. Extracts Using In vivo and In vitro Approaches
Okur, Mehmet Evren; Polat, Derya C.; Özbek, Hanefi; Yılmaz, Sezen; Yoltas, Ayşegül; Arslan, Rana (Bentham Science Publ LTD, 2018)Background and Objective: This paper is focused on evaluating the various biological activities of C. ovata var. palaestina extracts which could beneficially influence diabetes and its complications. Methods: Alloxan-induced ... -
Evaluation of the antithrombotic effects of Crataegus monogyna and Crataegus davisii in the carrageenan-induced tail thrombosis model
Arslan, Rana; Bektaş, Nurcan; Bor, Zeynep; Şener, Erol (Informa Healthcare, 2015)Context: Crataegus species are widely used as herbal medicines for preventing cardiovascular diseases (CVDs). However, there are no studies on the effects of Crataegus monogyna Jacq. (Rosaceae) and C. davisii Browicz on ... -
Hypoglycemic activity of Capparis ovata desf. var. palaestina zoh. methanol extract
Okur, Mehmet Evren; Özbek, Hanefi; Polat, Derya Çiçek; Yılmaz, Sezen; Arslan, Rana (University Sao Paulo, Conjunto Quimicas, 2018)Caper (Capparis ovata Desf. and Capparis spinosa L.) is naturally widespread in Turkey. Traditionally, buds, fruits, seeds and roots of this plant arc used as tonic, diuretic, anti-rheumatic, expectorant, antidiabetic, and ... -
The imidazoline receptors and ligands in pain modulations
Bektaş, Nurcan; Nemutlu, Dilara; Arslan, Rana (Wolters Kluwer Medknow Publications, 2015)Pain is an unpleasant experience and effects daily routine negatively. Although there are various drugs, many of them are not entirely successful in relieving pain, since pain modulation is a complex process involving ... -
Investigation for anti-inflammatory and anti-thrombotic activities of methanol extract of Capparis ovata buds and fruits
Bektaş, Nurcan; Arslan, Rana; Göğer, Fatih; Kırımer, Neşe; Öztürk, Yusuf (Elsevier Ireland LTD, 2012)Ethnopharmacological relevance: Capparis ovata Desf. has wide natural distribution in Turkey and it is consumed in pickled form. Flower buds, root bark, and fruits of the plant are used traditionally due to their analgesic, ... -
Investigation of Origanum onites, Sideritis congesta and Satureja cuneifolia essential oils for analgesic activity
Aydın, Süleyman; Öztürk, Yusuf; Arslan, Rana; Başer, K. Hüsnü Can (John Wiley & Sons LTD, 1996)Essential oils, obtained by Clevenger distillation, of Sideritis congesta P. H. Davis et Hub.Mor., Satureja cuneifolia Ten. and Origanum onites L. collected from two different localities were investigated for their analgesic ... -
Nepetalactone: A new opioid analgesic from Nepeta caesarea Boiss.
Aydın, Süleyman; Arslan, Rana; Öztürk, Yusuf; Başer, K. Hüsnü Can (Royal Pharmaceutical Soc Great Britain, 1998)The essential oils of Nepeta species including Nepeta phyllochlamys P. H. Davis, N. nuda L. ssp. nude, and N. caesarea Boiss. have been screened by use of the tail-flick and tail immersion (52.5 degrees C) methods. Of the ... -
The possible mechanisms of protocatechuic acid-induced central analgesia
Arslan, Rana; Aydın, Şule; Samur, Dilara Nemutlu; Bektaş, Nurcan (Elsevier Science BV, 2018)It is aimed to investigate the central antinociceptive effect of protocatechuic acid and the involvement of stimulation of opioidergic, serotonin 5-HT2A/2C. alpha 2-adrenergic and muscarinic receptors in protocatechuic ...