Kurum Yazarı "Demirayak, Şeref" Scopus İndeksli Yayınlar Koleksiyonu İçin Listeleme
-
Synthesis of platinum(II) complexes of 1-aryl-3-(benzimidazole-2-yl)- pyrazole-4-ketoximes and studies on their cytotoxic effects
In this research, synthesis of some complexes in the presence ofPt(II) were studied. The structure of the compounds were elucidated by IR, 1H-NMR, Mass and Elemental Analyses. The cytotoxicity of Pt-complex was evaluated. ... -
Synthesis of some 1-(2-arylvinyl)-3-arylpyrazino[1,2-a]benzimidazole derivatives and their antimicrobial activities
Some 1-(2-arylvinyl)-3-arylhyrazino[1,2-a]benzimidazole derivatives were synthesized, their structures were elucidated, and their antibacterial and antifungal activities were examined. None of the compounds proved to be ... -
Synthesis of some 2-[(benzazole-2-yl)thioacetyl]phenol derivatives and preliminary investigation on their vasodilatory activity
Turan, Gülhan; Demirayak, Şeref; Erol, Kevser; Özdemir, M. (1994)Some 2-[(benzazol-2-yl)thioacetyl]phenol derivatives were synthesized and their structures were elucidated by IR, NMR and microanalyses. The vasodilatory activity of the obtained compounds was investigated. -
Synthesis of some 3-arylamino-5-aryloxymethyl[1,2,4]triazole derivatives and their antimicrobial activity
Demirayak, Şeref; Benkli, Kadriye; Güven, Kıymet (1998)In this study, some 3-arylamino-5-aryloxymethyl[1,2,4]triazole derivatives were synthesized by reacting S-methyl-N'-arylisothiouronium iodide and 2- (aryloxy)alkanoic acid hydrazide. The structural elucidation of the ... -
Synthesis of some 4-phenyl/cyclohexyl-5-(l-phenoxyethyl)-3-[(3,5- diaryl-2-pyrazolinyl)acetyl]thio-4h-l,2,4-triazole derivatives and their antifungal activity [Bazi{dotless} 4-fenil/siklohegzil-5-(1-fenoksietil)-3-[(3,5-diaril-2-pirazolinil)aseti l]tiyo-4h-1,2,4-triazol türevlerinin sentezleri ve antifungal etkileri]
Turan, Gülhan; Kaplancıklı, Zafer Asım; Özdemir, Ahmet; Demirayak, Şeref; Uçucu, Ümit; Meriç, Asiye (2011)Triazole derivatives are the major chemical group of antifungal azole derivatives. Nowadays, the most frequently used triazoles are fluconazole and itraconazole. They posses a broad spectrum of antifungal activity and ... -
Synthesis of some 4-pyrrolylphenylthiazole derivatives and investigation of their antimicrobial activities
Demirayak, Şeref; Benkli, Kadriye; Sezer, C.; Erdeniz, H. (1997)In this study, some 2-substituted 4-[4-(pyrrol-1-yl)phenyl] thiazole derivatives were obtained reacting some 1,4-dicarbonyl compounds and 2-substituted 4-(4-aminophenyl) thiazoles. The latters were prepared by hydrolyzing ... -
Synthesis of some 5-methoxy-3-[(benzazole-2-yl)thioacetylamino]-2,3-dihydrobenzofuran derivatives and study of their antihypertensive activity [SYNTHESE DE CERTAINS DERIVES DE METHOXY-5 [(BENZAZOLE-2-YL)THIOACETYLAMINO]-3 DIHYDRO-2,3 BENZOFURANE ET RECHERCHE D'ACTIVITE ANTIHYPERTENSIVE]
Turan, Gülhan; Demirayak, Şeref; Erol, Kevser; Özdemir, M. (1994)In this study, some 5-methoxy-3-[(benzazole-2-yl) thioacetylamino]2,3-dihydrobenzofuran derivatives were synthesized and their structures were elucidated by IR, NMR and microanalyses. The antihypertensive activities of the ... -
Synthesis of some 5-methoxy-3-[(benzazole-2-yl)thioacétylamino]-2,3 -dihydrobenzofuran derivatives and investigation of antihypertensive activities [Synthèse de quelques dérivés de méthoxy-5 [(benzazole-2-yl)thioacétylamino]-3 dihydro-2,3 benzofuranne et recherche d'activité antihypertensive]
Turan, Gülhan; Demirayak, Şeref; Erol, Kevser; Özdemir, M. (1996)In this study, some 5-methoxy-3-[(benzazole-2-yl)thioacetylamino]-2,3-dihydrobenzofuran derivatives were synthesized and their structures were elucidated by IR, NMR and microanalyses. The antihypertensive activities of the ... -
Synthesis of some 6,7-disubstituted imidazo[4,5-g]quinoxaline derivatives as possible antimicrobials
In this study, some 6,7-disustituted imidazo[4,5-g]quinoxaline derivatives were synthesized by reacting 5,6-diaminobenzimidazole and some 1,2-dicarbonyl compounds. The antibacterial and antifungal activities of the compounds ... -
Synthesis of some 6,8-diarylimidazo[1,2-a]pyrazine derivatives by using either reflux or microwave irradiation method and investigation of their anticancer activities
Demirayak, Şeref; Kayagil, İsmail (Wiley, 2005)In order to obtain some 6,8-diarylimidazo[1,2-a]pyrazines, 1-(2-aryl-2-oxoethyl)-2-aryloylimidazole derivatives were reacted with ammonium acetate in acetic acid by using a new method different from that found in the ... -
Synthesis of some imidazolyl-thioacetyl-pyrazolinone derivatives and their antinociceptive and anticancer activitiesal
In this study, some 4-(1,5-diarylimidazol-2-yl)thioacetyl-1-phenyl-2,3- dimethyl-3-pyrazoline-5-one derivatives were prepared by reacting 4-(2-chloroacetyl)-1-phenyl-2,3-dimethyl-3-pyrazoline-5-one and 2-mercapto-1, ... -
Synthesis of some N-[4-(benzothiazole-2yl)phenyl]-2-aryloxyacetamide derivatives and their anticancer activities
Tay, Funda; Yurttaş, Leyla; Demirayak, Şeref (Informa Healthcare, 2012)In this study, some N-[4-(Benzothiazole-2-yl)phenyl]-2-aryloxyacetamide derivatives were prepared by reacting N-[4-(benzothiazole-2yl)phenyl]-2-chloroacetamide and different substituent phenol or thiophenol derivatives. ... -
Synthesis of some pyrido- and pyrazino-benzimidazole derivatives and their antifungal activity
Demirayak, Şeref; Güven, Kıymet (1995)Some 2-aryl-4-hydroxypyrido[1,2-a]benzimidazole and 1-substituted 3-arylpyrazino-[1,2-a]benzimidazole derivatives were synthesized using 1-(2-arylethan-2-on)2-acylbenzimidazole derivatives as starting materials. Antifungal ... -
Synthesis, antimicrobial and anticancer activities of some naphthylthiazolylamine derivatives
Tay, Funda; Erkan, Celal; Sarıözlü, Nalan Yılmaz; Ergene, Emel; Demirayak, Şeref (Allied Acad, 2017)New 4-naphthyl-2-aminothiazole derivatives were synthesized. The newly synthesized compounds were screened for their in vitro antimicrobial and anticancer activities. The results indicated that compound 5b namely ... -
Synthesis, characterization and antimicrobial activity of a Zn(II) complex with 1-(1H-benzoimidazol-2-yl)-ethanone thiosemicarbazone
Poyraz, Mehmet; Sarı, Musa; Güney, Ayşe; Demirci, Fatih; Demirayak, Şeref; Şahin, Ertan (Taylor & Francis LTD, 2008)A new Zn(II) complex with 1-(1H-benzoimidazol-2-yl)-ethanone thiosemicarbazone [Zn(NO(3))(H(2)O)(C(10)H(11)N(5)S)]NO(3) was prepared and characterized by elemental analyses, FT-IR, (1)H NMR spectroscopy, thermogravimetric ... -
Synthesis, crystal structure and biological activity of 1-(1H-benzoimidazol-2-yl)-ethanone thiosemicarbazone and its cobalt complex
Poyraz, Mehmet; Sarı, Musa; Demirci, Fatih; Koşar, Müberra; Demirayak, Şeref; Büyükgüngör, Orhan (Pergamon-Elsevier Science LTD, 2008)1-(1H-Benzoimidazol-2-yl)-ethanone thiosemicarbazone (H2L) (1) was obtained by the condensation reaction of 2-acetylbenzimidazole, thiosemicarbazide and acetic acid in ethanol. The novel cobalt(III) complex [Co(L)(HL)] 2 ... -
A theoretical approach to acidity-basicity behaviour of some biologically active 6-phenyl-4,5-dihydro-3(2H)-pyridazinone derivatives
Öğretir, Cemil; Yarlıgan, S; Demirayak, Şeref; Arslan, T (Elsevier Science BV, 2003)The acid dissociation constants, pK(a) values, of 12 biologically active 6-[p- or p- and m-substituted] phenyl-4,5-dihydro-3(2H)-pyridazinone derivatives were computed using semi-empirical methods. Correlations between the ... -
Thiazole-substituted benzoylpiperazine derivatives as acetylcholinesterase inhibitors
Şahin, Zafer; Ertaş, Merve; Bender, Ceysu; Bülbül, Emre F.; Berk, Barkin; Biltekin, Sevde N.; Demirayak, Şeref (Wiley, 2018)Hit, Lead & Candidate Discovery After acetylcholine is released into the synaptic cleft, it is reabsorbed or deactivated by acetylcholinesterase (AChE). Studies on Alzheimer's disease (AD) in the mid-20th century proved ...