Kurum Yazarı "Genç, Lütfi" Scopus İndeksli Yayınlar Koleksiyonu İçin Listeleme
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Preparation and characterization of nocodazole-loaded solid lipid nanoparticles
Genç, Lütfi (Informa Healthcare, 2014)Nocodazole (NCD) has more carcinogenic effect than similar drugs. Moreover, it has low drug release time and high particle size. Solid Lipid Nanoparticles (SLNs) have been evaluated for decrease in particle size and therefore ... -
Preparation and in vitro evaluation of controlled release hydrophilic matrix tablets of ketorolac tromethamine using factorial design
Genç, Lütfi; Jalvand, Esmaeil (Informa Healthcare, 2008)Controlled release matrix tablets of ketorolac tromethamine (KT) were prepared by direct compression technique using cellulose derivatives as hydroxypropylmethyl cellulose (HPMC), hydroxyethyl cellulose (HEC), and carboxymethyl ... -
Preparation of prolonged release clarithromycin microparticles for oral use and their in vitro evaluation
Genç, Lütfi; Demirel, Müzeyyen; Yazan, Yasemin (Pharmaceutical Soc Korea, 2006)Prolonged release microparticles of clarithromycin (CL) were prepared using Eudragit RL 100 and RS 100 by spray-drying and casting-drying techniques. For the characterization of those microparticles, preparation yield, ... -
Studies on controlled release dimenhydrinate from matrix tablet formulations
Genç, Lütfi; Bilaç, H.; Güler, E. (1999)In this study, controlled release dosage forms of dimenhydrinate were prepared with different polymers as MC, HEC, Carbopol 934, Eudragit RLPM and Eudragit NE 30 D at different concentrations (2.5-10%). Direct compression ... -
Studies on furazolidone suspension formulations
Genç, Lütfi; Güler, Erden (1992)[No abstract available] -
Studies on Polymeric and Lipid Nanoparticles of Ketoconazole for Ocular Administration
Demirel, Müzeyyen; Genç, Lütfi (Colegio Farmaceuticos Provincia De Buenos Aires, 2015)The fungistatic molecule ketoconazole was incorporated into polymeric (Eudragit (R) RS 100) and solid lipid (Gelucire (R) 44/14) nanoparticles by quasi-emulsion solvent evaporation technique aiming ocular application. ... -
Studies on trifluorothymidine ophthalmic formulations and their stability
Genç, Lütfi; Güler, Erden; Kurtcebe, D. (1994)[No abstract available] -
Studies on vaginal bioadhesive tablets of acyclovir
Genç, Lütfi; Oğuzlar, C; Güler, E (Govi-Verlag GMBH, 2000)Bioadhesive vaginal tablets were prepared using poly(acrylic acid) (PAA); Methylcellulose (MC), carboxymethyl cellulose (CMC), hydroxypropyl cellulose (HPC) and hydroxypropylmethyl cellulose (HPMC) as bioadhesive polymers ... -
Sustained release wax matrix formulations of ketorolac tromethamine with Compritol 888 ATO and HD 5 ATO
Genç, Lütfi; Hegazy, N. (2000)Sustained release wax matrix tablets of ketorolac tromethamine (KT) were prepared with different concentrations of Compritol 888 ATO (Glyceryl behenate) and HD 5 ATO (Glyceryl and Polyethylene glycol behenate). Tablet ... -
Validated HPLC method for the determination of nocodazole in solid lipid nanoparticle formulations [Kati{dotless} lipid nanopartikül formiilasyonlan İindeki nokodazol'ün belirlenmesiiçin onaylanmiş HPLC metodu]
Dikmen, Gökhan; Genç, Lütfi; Şener, E. (Turkish Pharmacists Association, 2014)Nocodazole (NCD) is an anti-neoplastic agent which exerts its effect in cells by interfering with the polymerization of microtubules. As NCD affects the cytoskeleton, it is often used incell biology experiments as a control. ... -
Vibrational spectroscopic investigation of methyl(5-[2-thienylcarbonyl]-1H-benzimidazol-2-yl: A comparative density functional study
Alver, Özgür; Parlak, Cemal; Kaya, M. Fatih; Dikmen, Gökhan; Genç, Lütfi (Maik Nauka/Interperiodica/Springer, 2014)FT-IR and Raman spectra of methyl(5-[2-thienylcarbonyl]-1H-benzimidazol-2-yl (nocodazole) are experimentally examined in the region of 4000-400 cm(-1). The optimized geometric parameters, conformational equilibria, normal ... -
Vitamin B-12-loaded solid lipid nanoparticles as a drug carrier in cancer therapy
Genç, Lütfi; Kutlu, Hatice Mehtap; Güney, Gamze (Informa Healthcare, 2015)Nanostructure-mediated drug delivery, a key technology for the realization of nanomedicine, has the potential to improve drug bioavailability, ameliorate release deviation of drug molecules and enable precision drug ...