Yazar "Sırmagül, Başar" için listeleme
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Acute and Subchronic Toxic Effects of the Fruits of Physalis peruviana L.
Perk, Başak Özlem; Ilgın, Sinem; Atlı Eklioğlu, Özlem; Duymuş, Hale Gamze; Sırmagül, Başar (Hindawi Publishing Corporation, 2013)The fruit of Physalis peruviana L. (PPL) has been traditionally used as antispasmodic, diuretic, antiseptic, sedative, and analgesic all over the world. We aimed to perform qualitative content analysis of the fruits of PPL ... -
Assessment of the Endothelial Functions in Monocrotaline-induced Pulmonary Hypertension
Sırmagül, Başar; Ilgın, Sinem; Atlı Eklioğlu, Özlem; Usanmaz, Suzan Emel; Demirel-Yılmaz, Emine (Taylor & Francis Inc, 2013)Pulmonary hypertension (PH) is a life-threatening disease that causes endothelial dysfunction in the pulmonary vascular bed. Systemic endothelial dysfunction has also been reported in PH. This study compared the systemic ... -
Cyclosporine-A incorporated cationic solid lipid nanoparticles for ocular delivery
Başaran, Ebru; Demirel, Müzeyyen; Sırmagül, Başar; Yazan, Yasemin (Taylor & Francis LTD, 2010)In the present study, Cyclosporine A (CsA) was successfully incorporated into cationic solid lipid nanoparticles (SLN) for ocular application. Physicochemical characterizations of SLNs were analysed in detail during the ... -
The effect of polytherapy on serum concentrations of traditional antiepileptics: A retrospective study
Atlı Eklioğlu, Özlem; Ilgın, Sinem; Sırmagül, Başar (Elsevier Ireland LTD, 2011)… -
Effects of Everolimus in Combination with Sildenafil in Monocrotaline-induced Pulmonary Hypertension in Rats
Ilgın, Sinem; Burukoğlu, Dilek; Atlı Eklioğlu, Özlem; Sırmagül, Başar (Humana Press Inc, 2012)In our study, we investigated the efficacy of everolimus in combination with sildenafil on hemodynamic and morphological parameters in rats with monocrotaline-induced pulmonary hypertension (PH). Right ventricular pressure ... -
The effects of gender difference on monocrotaline-induced pulmonary hypertension in rats
Bal, E.; Ilgın, Sinem; Atlı Eklioğlu, Özlem; Ergün, Bülent; Sırmagül, Başar (SAGE Publications LTD, 2013)The present study aimed to compare the effect of gender difference on hemodynamic consequences in the development of monocrotaline (MCT)-induced pulmonary hypertension in rat. The effect of antioxidant enzyme systems on ... -
Enhanced bioavailability of cinnarizine using solid dispersion: In vitro and in vivo evaluation
Demirel, Müzeyyen; Büyükköroğlu, G.; Sırmagül, Başar; Kalava, B. S.; Öztürk, Nilgün; Yazan, Yasemin (Bentham Science Publishers B.V., 2015)The aim of this study was to modify the release and thus enhance the bioavailability of acalcium antagonist cinnarizine whose aqueouse solubility is low and half-life is short. For this purpose, solid dispersion system was ... -
Is MCT-induced toxicity limited to the pulmonary vasculature?
Ilgın, Sinem; Atlı Eklioğlu, Özlem; Sırmagül, Başar; Yılmaz, E. Demirel (Elsevier Ireland LTD, 2011)… -
Is N-acetyl cysteine protective against monocrotaline-induced toxicity?
Karagöz, Şerife; Ilgın, Sinem; Atlı Eklioğlu, Özlem; Perk, Başak Özlem; Burukoğlu, Dilek; Ergün, Bülent; Sırmagül, Başar (Taylor & Francis Inc, 2013)Monocrotaline (MCT) is a pyrrolizidine alkaloid which induces cardio-pulmonary toxicity and hepatotoxicity in animals and humans. MCT is frequently ingested because of food grain contamination accidentally or in the form ... -
Matrix metalloproteinases are possible targets in monocrotaline-induced pulmonary hypertension: investigation of anti-remodeling effects of alagebrium and everolimus
Atlı Eklioğlu, Özlem; Ilgın, Sinem; Ergün, Bülent; Burukoğlu, Dilek; Musmul, Ahmet; Sırmagül, Başar (Turkish Soc Cardiology, 2017)Objective: In our study, sildenafil alone and everolimus or alagebrium in combination with sildenafil were investigated in terms of their additional therapeutic and anti-remodeling activity in monocrotaline-induced pulmonary ... -
Polymeric Cyclosporine-A Nanoparticles for Ocular Application
Başaran, Ebru; Demirel, Müzeyyen; Sırmagül, Başar; Yazan, Yasemin (Amer Scientific Publishers, 2011)In the present study, cyclosporine A (CsA) was incorporated successfully into cationic Eudragit(R) RS 100 nanoparticles (EPNs) aiming ocular application. Physicochemical characterization of the EPNs prepared was performed ... -
Some pyridazinone and phthalazinone derivatives and their vasodilator activities
Demirayak, Şeref; Karaburun, Ahmet Çağrı; Kayagil, İsmail; Erol, K.; Sırmagül, Başar (Pharmaceutical Society of Korea, 2004)In this study, 6-[(4-arylidene-2-phenyl-5-oxoimidazolin-1-yl)phenyl]-4,5- dihydro-3(2H)-pyridazinone and 4-[(4-arylidene-2-phenyl-5-oxoimidazolin-1-yl) phenyl]-1(2H)-phthalazinone derivatives were synthesized by reacting ...
