Yazar "Karaosmanoğlu, Oğuzhan" için listeleme
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Cytotoxicity of 11 naturally occurring phenolics and terpenoids from Kenyan flora towards human carcinoma cells
Kuete, Victor; Omosa, Leonidah K.; Midiwo, J. O.; Karaosmanoğlu, Oğuzhan; Sivas, Hakan (Elsevier B.V., 2018)Background: Cancer constitutes a major hurdle worldwide and its treatment mainly relies on chemotherapy. Objectives: The present study was designed to evaluate the cytotoxicity of 11 naturally occurring compounds including ... -
Cytotoxicity of seputhecarpan D, thonningiol and 12 other phytochemicals from African flora towards human carcinoma cells
Kuete, Victor; Ngnintedo, Dominique; Fotso, Ghislain W.; Karaosmanoğlu, Oğuzhan; Ngadjui, Bonaventure T.; Keumedjio, Felix; Sivas, Hülya (Bmc, 2018)Background: Despite the remarkable progress in cancer therapy in recent years, this disease still remains a serious public health concern. The use of natural products has been and continues to be one of the most effective ... -
Cytotoxicity of the methanol extracts of Elephantopus mollis, Kalanchoe crenata and 4 other Cameroonian medicinal plants towards human carcinoma cells
Kuete, Victor; Fokou, Fabrice W.; Karaosmanoğlu, Oğuzhan; Beng, Veronique P.; Sivas, Hülya (Bmc, 2017)Background: Cancer still constitutes one of the major health concerns globally, causing serious threats on patients, their families, and the healthcare system. Methods: In this study, the cytotoxicity of the methanol extract ... -
Identification of biomarkers associated with partial epithelial to mesenchymal transition in the secretome of slug over-expressing hepatocellular carcinoma cells
Karaosmanoğlu, Oğuzhan; Banerjee, Sreeparna; Sivas, Hülya (Springer, 2018)Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths worldwide. Complete epithelial to mesenchymal transition (EMT) has long been considered as a crucial step for metastasis initiation. It ... -
In vitro cytotoxicity of compounds isolated from Desbordesia glaucescens against human carcinoma cell lines
Kuete, Victor; Mafodong, F. L. Dongmo; Çelik, I.; Fobofou, S. A. T.; Ndontsa, B. L.; Karaosmanoğlu, Oğuzhan; Sivas, Hülya (Elsevier Science BV, 2017)Malignancies constitute a global health concern and chemotherapy remains the main mode of treatment. The present study was designed to evaluate the cytotoxicity of 8 compounds from Desbordesia glaucescens namely ... -
Kemoterapi ajanlarına dirençli hepatosellülar karsinoma hücrelerinde olası biyoişaretlerin in vitro araştırılması
Sivas, Hülya; Anadolu Üniversitesi, Fen Bilimleri Enstitüsü, Biyoloji Anabilim Dalı; Karaosmanoğlu, Oğuzhan (Tez (doktora) - Anadolu Üniversitesi, 2018)Hepatosellülar karsinoma (HSK) kanser ilişkili ölümler sıralamasında dünyada ikincidir. Epitel-mezenkimal geçiş (EMT) metastaz başlaması için önemli bir programdır. Buna rağmen, pek çok kanser hücresi bütün epitel karakterleri ... -
Two new pterocarpans and a new pyrone derivative with cytotoxic activities from Ptycholobium contortum (NEBr.) Brummitt (Leguminosae): revised NMR assignment of mundulea lactone
Ngnintedo, Dominique; Fotso, Ghislain W.; Kuete, Victor; Nana, Frederic; Sandjo, Louis P.; Karaosmanoğlu, Oğuzhan; Andrae-Marobela, Kerstin (Springeropen, 2016)Background: Ptycholobium is a genus related to Tephrosia which comprises only three species. Compared to Tephrosia, which has been phytochemically and pharmacologically studied, Ptycholobium species have only few or no ... -
Yeni sentezlenmiş aril (3-metil-benzofuran-2-il) keton türevlerinin ve vulpunik asitin sitotoksik ve apoptotik etkisinin normal ve kanserli hücrelerde in vitro araştırılması
Karaosmanoğlu, Oğuzhan (Anadolu Üniversitesi, 2014)Benzofuranlar pek çok doğal bileşende yaygın olarak bulunduğu için ilgi toplamış bileşiklerdendir. Vulpinik asit biyolojik etkisi olduğu bilinen liken metabolitlerindendir. Bu tezde yeni sentezlenmiş üç aril (3-metil-ben ...
