Yazar "Ilgin, Sinem" için listeleme
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Synthesis of novel benzimidazole-oxadiazole derivatives as potent anticancer activity
Cevik, Ulviye Acar; Osmaniye, Derya; Cavusoglu, Betul Kaya; Saglik, Begum Nurpelin; Levent, Serkan; Ilgin, Sinem; Kaplancikli, Zafer Asim (Springer Birkhauser, 2019)DNA topoisomerase I regulates DNA topological structure in many cellular metabolic processes and is a validated target for the development of antitumor agents. in this work, a series of novel 2-[(5-(4-(5(6)-substituted-1 ... -
Synthesis, Docking Studies and Biological Activity of New Benzimidazole- Triazolothiadiazine Derivatives as Aromatase Inhibitor
Cevik, Ulviye Acar; Cavusoglu, Betuel Kaya; Saglik, Beguem Nurpelin; Osmaniye, Derya; Levent, Serkan; Ilgin, Sinem; Kaplancikli, Zafer Asim (Mdpi, 2020)In the last step of estrogen biosynthesis, aromatase enzyme catalyzes the conversion of androgens to estrogens. Aromatase inhibition is an important way to control estrogen-related diseases and estrogen levels. in this ...
