Yazar "Hussein, Weiam" için listeleme
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Design, Synthesis and Biological Evaluation of Novel N-Pyridyl-Hydrazone Derivatives as Potential Monoamine Oxidase (MAO) Inhibitors
Turan, Gülhan; Hussein, Weiam; Sağlık, Begüm Nurpelin; Tabbi, Aouatef; Korkut, Büşra (MDPI, 2018)A new series of N-pyridyl-hydrazone derivatives was synthesized by using a simple and efficient method. The final compounds obtained were screened for their inhibitory potency against monoamine oxidase (MAO) A and B. The ... -
Fighting Against Alzheimer's Disease: Synthesis of New Pyrazoline and Benzothiazole Derivatives as New Acetylcholinesterase and MAO Inhibitors
Turan, Gülhan; Hussein, Weiam; Sağlık, Begüm Nurpelin; Baysal, Merve; Kaplancıklı, Zafer Asım (Bentham Science Publ LTD, 2018)Background: Alzheimer's Disease (AD) is a complicated neurodegenerative disorder with a multifaceted pathogenesis. AD, characterized by gradual memory loss, falling in language ability and other cognitive deterioration, ... -
Synthesis and antimicrobial activity of new 2-((1-furan-2-yl)ethylidene)hydrazono)-4-phenylthiazol-3(2H)-amine derivatives and their schiff bases with 4-nitrobenzaldehyde
Turan, Gülhan; Sağlık, Begüm Nurpelin; Çevik, Ulviye Acar; Levent, Serkan; Ilgın, Sinem; Hussein, Weiam (Taylor & Francis LTD, 2018)A new series of 2-((1-furan-2-yl)ethylidene)hydrazono)-4-substitutedphenylthiazol-3(2H)-amines (2a-2o) and their Schiff bases (3a-3o) from 4-nitrobenzaldehyde were synthesized. The chemical structures of all the synthesized ... -
Synthesis and Biological Evaluation of New Cholinesterase Inhibitors for Alzheimer's Disease
Hussein, Weiam; Sağlık, Begüm Nurpelin; Levent, Serkan; Korkut, Büsra; Ilgın, Sinem; Özkay, Yusuf; Kaplancıklı, Zafer Asım (MDPI, 2018)Alzheimer's disease (AD) is a neurodegenerative disorder mostly influencing the elderly, and causes death due to dementia. The main pathogenic feature connected with the progression of this multifactorial disease is the ... -
Synthesis and Evaluation of N-[1-(((3,4-Diphenylthiazol-2(3H)-ylidene)amino)methyl)cyclopentyl]acetamide Derivatives for the Treatment of Diseases Belonging to MAOs
Turan, Gülhan; Tabbi, Aouatef; Hussein, Weiam; Karaduman, Abdullah Burak; Sağlık, Begüm Nurpelin; Özkay, Yusuf (Hindawi LTD, 2018)A series of N-[1-(((3,4-diphenylthiazol-2(3H)-ylidene)amino)methyl)cyclopentyl]acetamide derivatives (4a-4i) were synthesized in good yield and assayed for their inhibitory potency against monoamine oxidase (MAO) isoforms. ...
