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An Adaptive Algorithm for Detection of Multiple-Type, Positively Stained Nuclei in IHC images with minimal Prior Information: Application to OLIG2 Staining Gliomas

Akakin, Hatice Çınar; Gökozan, Hamza; Otero, Jose; Gürcan, Metin N. (Spie-Int Soc Optical Engineering, 2015)

We propose a method to detect and segment the oligodendrocytes and gliomas in OLIG2 immunoperoxidase stained tissue sections. Segmentation of cell nuclei is essential for automatic, fast, accurate and consistent analysis ...