Yazar "Berk, Barkın" için listeleme
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Bazı 2-piridil-4-sübstitüe fenol tiyazol türevlerinin sentezi ve aromataz inhibisyonu etkilerinin araştırılması
Ertaş, Merve (Anadolu Üniversitesi, 2015)Araştırmalar, tiyazol türevi bileşiklerin, prostat kanserinde tedavi edici, Mycobacterium tuberculosis H37Rv inhibitörü, glutatyon S-transferaz pi inhibitörü ve trombosit agregasyon inhibitörü olduğunu göstermektedir. ... -
Pyridine-substituted thiazolylphenol derivatives: Synthesis, modeling studies, aromatase inhibition, and antiproliferative activity evaluation
Ertaş, Merve; Şahin, Zafer; Berk, Barkın; Yurttaş, Leyla; Biltekin, Sevde N.; Demirayak, Şeref (Wiley-V C H Verlag GMBH, 2018)Drugs used in breast cancer treatments target the suppression of estrogen biosynthesis. During this suppression, the main goal is to inhibit the aromatase enzyme that is responsible for the cyclization and structuring of ... -
Studies on non-steroidal inhibitors of aromatase enzyme; 4-(aryl/heteroaryl)-2-(pyrimidin-2-yl)thiazole derivatives
Şahin, Zafer; Ertaş, Merve; Berk, Barkın; Biltekin, Sevde Nur; Yurttaş, Leyla; Demirayak, Şeref (Pergamon-Elsevier Science LTD, 2018)Steroidal and non-steroidal aromatase inhibitors target the suppression of estrogen biosynthesis in the treatment of breast cancer. Researchers have increasingly focused on developing non-steroidal derivatives for their ...