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Design and characterization of nanocarriers loaded with Levofloxacin for enhanced antimicrobial activity; physicochemical properties, in vitro release and oral acute toxicity
Siafaka, Panoraia; Okur, Mehmet Evren; Ayla, Şule; Er, Sevda; Çaglar, Emre Şefik; Okur, Neslihan Üstündağ (University Sao Paulo, Conjunto Quimicas, 2019)Inorganic and carbon based nanomaterials are widely used against several diseases, such as cancer, autoimmune diseases as well as fungi and bacteria colonization. In this work, Santa Barbara Amorphous mesoporous silica ... -
A novel approach for skin infections: Controlled release topical mats of poly (lactic acid)/poly(ethylene succinate) blends containing Voriconazole
Okur, Neslihan Üstündağ; Filippousi, Maria; Okur, Mehmet Evren; Ayla, Şule; Çaglar, Emre Şefik; Yoltas, Ayşegül; Siafaka, Panoraia, I (Elsevier Science BV, 2018)The oral and injectable formulations of Voriconazole (VRZ), a known antifungal agent with low solubility, seem to cause severe side effects. Consequently, topical application of VRZ could be advantageous for skin fungal ...